Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Endocrine Diseases
Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include:
- Growth and development
- Metabolism - digestion, elimination, breathing, blood circulation and maintaining body temperature
- Sexual function
- Reproduction
- Mood
If your hormone levels are too high or too low, you may have a hormone disorder. Hormone diseases also occur if your body does not respond to hormones the way it is supposed to. Stress, infection and changes in your blood's fluid and electrolyte balance can also influence hormone levels.
In the United States, the most common endocrine disease is diabetes. There are many others. They are usually treated by controlling how much hormone your body makes. Hormone supplements can help if the problem is too little of a hormone.
It sits within Endocrine System.
The lead U.S. institute for this subject is the National Institute of Diabetes and Digestive and Kidney Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Endocrine Diseases
35,893 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)National Cancer Institute (NCI)
- Advancing Diabetes Management for People With Physical Disabilities Optimally Through Primary Care-Based Telehealth (ADDOPT)University of Alabama at Birmingham
- A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightNovo Nordisk A/S
- Relationship Between Red Cell Distribution Width (RDW) and HbA1C in Patients With Type 2 Diabetes Mellitus After Glycemic ControlNew Valley University
- Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid TumorsNovartis Pharmaceuticals
- Evaluation of Serum Preptin Levels in Patients With Polycystic Ovary SyndromeGÜLDEN ANATACA
Research already completed
- Tumor-Derived FGF19University of Central Florida
- Diabetes Prevention Program Outcomes StudyNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or OverweightEli Lilly and Company
- DIA:CONN P8(Smart Insulin Pen) Study in Diabetes PatientsG2e Co., Ltd
- Vacuum Compression Therapy for Chronic Lower Limb UlcersBTL Industries Ltd.
- A Study of HRS9531 Versus Semaglutide Once Weekly as Add-on Therapy to Metformin Monotherapy or in Combination With SGLT2 Inhibitors in Participants With Type 2 DiabetesFujian Shengdi Pharmaceutical Co., Ltd.
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Endocrine DiseasesNational Institute of Diabetes and Digestive and Kidney Diseases
- Endocrine SystemNemours Foundation
- Overview of the Endocrine SystemEnvironmental Protection Agency
Related Issues
- Bisphenol A (BPA)National Institute of Environmental Health Sciences
- Endocrine DisruptorsNational Institute of Environmental Health Sciences
- Endocrine-Disrupting Chemicals (EDCs)Endocrine Society
- Overview of Endocrine DisruptionEnvironmental Protection Agency
Genetics
- 17-beta hydroxysteroid dehydrogenase 3 deficiency: MedlinePlus GeneticsNational Library of Medicine
- 46,XX testicular difference of sex development: MedlinePlus GeneticsNational Library of Medicine
- 5-alpha reductase deficiency: MedlinePlus GeneticsNational Library of Medicine
- Aromatase deficiency: MedlinePlus GeneticsNational Library of Medicine
- Aromatase excess syndrome: MedlinePlus GeneticsNational Library of Medicine
- Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy: MedlinePlus GeneticsNational Library of Medicine
- Central precocious puberty: MedlinePlus GeneticsNational Library of Medicine
- Cytochrome P450 oxidoreductase deficiency: MedlinePlus GeneticsNational Library of Medicine
- Familial male-limited precocious puberty: MedlinePlus GeneticsNational Library of Medicine
- Isolated growth hormone deficiency: MedlinePlus GeneticsNational Library of Medicine
- Kallmann syndrome: MedlinePlus GeneticsNational Library of Medicine
- Leydig cell hypoplasia: MedlinePlus GeneticsNational Library of Medicine
- McCune-Albright syndrome: MedlinePlus GeneticsNational Library of Medicine
- Multiple endocrine neoplasia: MedlinePlus GeneticsNational Library of Medicine
- Swyer syndrome: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: Endocrine System DiseasesNational Institutes of Health
- ClinicalTrials.gov: Multiple Endocrine NeoplasiaNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Endocrine System Diseases. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Endocrine Diseases, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.