Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Thyroid Diseases
Your thyroid is a small, butterfly-shaped gland in the front of your neck. It makes hormones that control the way the body uses energy. These hormones affect nearly every organ in your body and control many of your body's most important functions. For example, they affect your breathing, heart rate, weight, digestion, and moods.
Thyroid diseases cause your thyroid to make either too much or too little of the hormones. Some of the different thyroid diseases include:
- Goiter, an enlargement of the thyroid gland
- Hyperthyroidism, which happens when your thyroid gland makes more thyroid hormones than your body needs
- Hypothyroidism, which happens when your thyroid gland does not make enough thyroid hormones
- Thyroid cancer
- Thyroid nodules, lumps in the thyroid gland
- Thyroiditis, swelling of the thyroid
To diagnose thyroid diseases, your health care provider may use a medical history, physical exam, and thyroid tests. In some cases, your provider may also do a biopsy.
Treatment depends on the problem, how severe it is, and what your symptoms are. Possible treatments may include medicines, radioiodine therapy, or thyroid surgery.
Dept. of Health and Human Services Office on Women's Health
It sits within Endocrine System.
The lead U.S. institute for this subject is the National Institute of Diabetes and Digestive and Kidney Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Thyroid Diseases
2,418 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)National Cancer Institute (NCI)
- 177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid CancerNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer SurvivorsUniversity of Southern California
- Telehealth Music Therapy for Adults With Endocrine Disorder and DepressionAppalachian State University
- Nanosecond Pulsed Field Ablation in the Management of T1N0M0 Papillary Thyroid CarcinomaM.D. Anderson Cancer Center
- Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' DiseaseBiohaven Therapeutics Ltd.
Research already completed
- Thyroid Fine Needle Biopsy and Impact on Pain and Diagnostic AdequacyIzmir Ataturk Training and Research Hospital
- The Use of Candy and Honey in Decreasing Salivary Gland Damage Following Radioiodine Therapy for Thyroid CancerCyprus University of Technology
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Thyroid and Parathyroid HormonesEndocrine Society
- Thyroid DiseaseDepartment of Health and Human Services, Office on Women's Health
- Thyroid Disease (for Parents)Nemours Foundation
Diagnosis and Tests
- Needle BiopsyMayo Foundation for Medical Education and Research
- Thyroid AntibodiesNational Library of Medicine
- Thyroid Scan and UptakeRadiological Society of North America
- Thyroid TestsNational Institute of Diabetes and Digestive and Kidney Diseases
- Thyroxine (T4) TestNational Library of Medicine
- Triiodothyronine (T3) TestsNational Library of Medicine
- TSH (Thyroid-stimulating hormone) testNational Library of Medicine
- Ultrasound - ThyroidRadiological Society of North America
- Ultrasound-Guided Thyroid BiopsyRadiological Society of North America
Treatments and Therapies
- Complementary and Alternative Medicine in Thyroid Disease (CAM)American Thyroid Association
- Older Therapies Aren't Necessarily Better for Thyroid Hormone ReplacementFood and Drug Administration
- Thyroid Hormone TreatmentAmerican Thyroid Association
- Thyroid SurgeryAmerican Thyroid Association
- ThyroidectomyMayo Foundation for Medical Education and Research
Related Issues
- Celiac Disease and Thyroid ConditionsGluten Intolerance Group
- Pendred SyndromeNational Institute on Deafness and Other Communication Disorders
- Potassium Iodide (KI)Centers for Disease Control and Prevention
Genetics
- Inherited thyroxine-binding globulin deficiency: MedlinePlus GeneticsNational Library of Medicine
- Pendred syndrome: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: GoiterNational Institutes of Health
- ClinicalTrials.gov: Thyroid DiseasesNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Thyroid Diseases. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Thyroid Diseases, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.