Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Pancreatic Diseases
The pancreas is a gland behind your stomach and in front of your spine. It produces juices that help break down food and hormones that help control blood sugar levels. Problems with the pancreas can lead to many health problems. These include:
- Pancreatitis, or inflammation of the pancreas: This happens when digestive enzymes start digesting the pancreas itself
- Pancreatic cancer
- Cystic fibrosis, a genetic disorder in which thick, sticky mucus can also block tubes in your pancreas
The pancreas also plays a role in diabetes. In type 1 diabetes, the beta cells of the pancreas no longer make insulin because the body's immune system has attacked them. In type 2 diabetes, the pancreas loses the ability to secrete enough insulin in response to meals.
It sits within Digestive System and Endocrine System.
The lead U.S. institute for this subject is the National Institute of Diabetes and Digestive and Kidney Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Pancreatic Diseases
7,266 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)National Cancer Institute (NCI)
- Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic CancerNational Cancer Institute (NCI)
- Safety and Efficacy of Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA) in the Treatment of Pancreatic LesionsThe University of Texas Health Science Center, Houston
- AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid TumorsAmgen
- Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy in Patients With Cancer-Related Celiac PainUniversity Health Network, Toronto
- A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)Bristol-Myers Squibb
Research already completed
- Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid TumorsNational Cancer Institute (NCI)
- Impact of Telerehabilitation Training on Pediatric Cystic Fibrosis Patients: An Exploratory StudyMemorialCare Health System
- Support Through Remote Observation and Nutrition Guidance (STRONG) Program for Pancreatic Cancer PatientsH. Lee Moffitt Cancer Center and Research Institute
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Pancreas DiseaseNational Pancreas Foundation
- Power of Your Pancreas: Keep Your Digestive Juices FlowingNational Institutes of Health
Diagnosis and Tests
- Amylase TestNational Library of Medicine
- Chymotrypsin in StoolNational Library of Medicine
- Endoscopic Retrograde Cholangiopancreatography (ERCP)National Institute of Diabetes and Digestive and Kidney Diseases
- Lactate Dehydrogenase (LDH) Isoenzymes TestNational Library of Medicine
- Lactate Dehydrogenase (LDH) TestNational Library of Medicine
- Lipase TestNational Library of Medicine
- Stool ElastaseNational Library of Medicine
Treatments and Therapies
- Pain Treatment and ManagementNational Pancreas Foundation
Living With
- A Black/African American's Guide to Pancreas DiseaseNational Pancreas Foundation
Genetics
- Shwachman-Diamond syndrome: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: Pancreatic DiseasesNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Pancreatic Diseases. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Pancreatic Diseases, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.