Also called: DM · Diabetes mellitus
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Diabetes
Diabetes, also known as diabetes mellitus, is a disease in which your blood glucose, or blood sugar, levels are too high. Glucose is your body's main source of energy. Your body can make glucose, but it also comes from the food you eat. Insulin is a hormone made by your pancreas. Insulin helps move glucose from your bloodstream into your cells, where it can be used for energy.
If you have diabetes, your body can't make insulin, can't use insulin as well as it should, or both. Too much glucose stays in your blood and doesn't reach your cells. This can cause glucose levels to get too high. Over time, high blood glucose levels can lead to serious health conditions. But you can take steps to manage your diabetes and try to prevent these health problems.
There are different types of diabetes:
- Type 1 diabetes. If you have type 1 diabetes, your body makes little or no insulin. It happens when your immune system attacks and destroys the cells that produce insulin.
- Type 2 diabetes. This is the most common form of diabetes. If you have type 2 diabetes, your body may still be able to make insulin, but your cells don't respond well to insulin. They can't easily take up enough glucose from your blood.
- Gestational diabetes. This is a form of diabetes that develops during pregnancy. It happens when your body can't make the extra insulin it needs during pregnancy.
The different types of diabetes have different causes:
- Researchers think type 1 diabetes is caused by genes and factors in the environment that might trigger the disease.
- Type 2 diabetes is caused by several factors, including lifestyle factors and genes. The lifestyle factors include not being physically active and being overweight or having obesity.
- Researchers think gestational diabetes is caused by the hormonal changes of pregnancy along with genetic and lifestyle factors.
The different types of diabetes have different risk factors:
- You can develop type 1 diabetes at any age, but it most often starts in childhood. Having a parent or sibling with type 1 diabetes may increase your chance of developing it.
- You are at higher risk of developing type 2 diabetes if you:
- Are overweight or have obesity.
- Are over age 35. Children, teenagers, and younger adults can get diabetes, but it is more common in middle-aged and older adults.
- Have a family history of diabetes.
- Have prediabetes. This means that your blood glucose is higher than normal, but it's not high enough to be called diabetes.
- Had gestational diabetes.
- Have given birth to a baby weighing 9 pounds or more.
- Are African American, American Indian, Asian American, Hispanic/Latino, or Pacific Islander.
- Are not physically active.
- Have certain other health conditions, such as high blood pressure or polycystic ovary syndrome (PCOS).
- Are overweight or have obesity.
- Have a family history of diabetes.
- Had gestational diabetes in a previous pregnancy.
- Have given birth to a baby weighing 9 pounds or more.
- Have polycystic ovary syndrome (PCOS).
- Are African American, Hispanic/Latino, American Indian, Alaska Native, Native Hawaiian, or Pacific Islander.
The symptoms of diabetes may include:
- Feeling very thirsty
- Feeling very hungry
- Urinating (peeing) more often, including at night
- Fatigue
- Blurry vision
- Numbness or tingling in the feet or hands
- Sores that do not heal
- Losing weight without trying
But it's important to know that your symptoms may vary, depending on which type you have:
- The symptoms of type 1 diabetes usually come on quickly and can be severe.
- With type 2 diabetes, the symptoms often develop slowly, over several years. The symptoms can be so mild that you might not even notice them.
- Gestational diabetes often has no symptoms. If you do have symptoms, they may be mild. If you are pregnant, you will usually be screened for this condition between 24 and 28 weeks of pregnancy.
To find out if you have diabetes, your health care provider will use one or more glucose blood tests. There are several types, including the A1C test.
Treatment for diabetes involves managing your blood glucose levels:
- If you have type 1 diabetes, you will need to take daily doses of insulin, either by injection or through a special pump. Some people also need to take another type of diabetes medicine that works with insulin.
- If you have type 2 diabetes, you may be able to manage or even reverse it by making lifestyle changes. These include eating a healthy diet, staying at healthy weight, and getting regular physical activity. Some people also need to take diabetes medicines to manage their diabetes.
- If you have gestational diabetes, you may be able to lower your glucose levels by eating a healthy diet and getting regular exercise. But be sure to talk to your provider about your treatment options. Gestational diabetes usually goes away after you give birth. But you will have a higher risk of developing type 2 diabetes later.
Checking your blood glucose levels is also an important part of managing your diabetes. Ask your provider about the best way to check your blood glucose level and how often you should check it.
Type 1 diabetes can't be prevented.
You may be able to delay or prevent type 2 diabetes through the same lifestyle changes that are used to manage diabetes (eating a healthy diet, staying at a healthy weight, and getting regular physical activity). These lifestyle changes may also help prevent gestational diabetes.
It sits within Older Adults, Endocrine System, Metabolic Problems and Diabetes Mellitus.
The lead U.S. institute for this subject is the National Institute of Diabetes and Digestive and Kidney Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Diabetes
24,177 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Advancing Diabetes Management for People With Physical Disabilities Optimally Through Primary Care-Based Telehealth (ADDOPT)University of Alabama at Birmingham
- A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightNovo Nordisk A/S
- Relationship Between Red Cell Distribution Width (RDW) and HbA1C in Patients With Type 2 Diabetes Mellitus After Glycemic ControlNew Valley University
- SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTNMedtronic Vascular
- Telehealth Music Therapy for Adults With Endocrine Disorder and DepressionAppalachian State University
- Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic CancerAulos Bioscience, Inc.
Research already completed
- Diabetes Prevention Program Outcomes StudyNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or OverweightEli Lilly and Company
- DIA:CONN P8(Smart Insulin Pen) Study in Diabetes PatientsG2e Co., Ltd
- The Influence of Time-Restricted Eating in Patients With Metabolic SyndromeUniversity of California, San Diego
- Vacuum Compression Therapy for Chronic Lower Limb UlcersBTL Industries Ltd.
- A Study of HRS9531 Versus Semaglutide Once Weekly as Add-on Therapy to Metformin Monotherapy or in Combination With SGLT2 Inhibitors in Participants With Type 2 DiabetesFujian Shengdi Pharmaceutical Co., Ltd.
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Diagnosis and Tests
- A1C: MedlinePlus Health TopicNational Library of Medicine
- At-Home Medical TestsNational Library of Medicine
- Blood Glucose TestNational Library of Medicine
- Diabetes Tests and DiagnosisNational Institute of Diabetes and Digestive and Kidney Diseases
- Glucagon Blood TestNational Library of Medicine
- Glucose in Urine TestNational Library of Medicine
Treatments and Therapies
- Diabetes Medicines: MedlinePlus Health TopicNational Library of Medicine
Living With
- Changing Your Habits for Better HealthNational Institute of Diabetes and Digestive and Kidney Diseases
- Diabetes and DigestionAmerican Heart Association
- Diabetes and Mental HealthCenters for Disease Control and Prevention
- Diabetic Diet: MedlinePlus Health TopicNational Library of Medicine
- DKA: Signs, Symptoms, and TreatmentAmerican Diabetes Association
Related Issues
- A1C Test and Race/EthnicityNational Institute of Diabetes and Digestive and Kidney Diseases
- Chronic Kidney Disease, Diabetes, and Heart DiseaseCenters for Disease Control and Prevention
- Health Consequences of Early Exposure to SugarNational Institutes of Health
- Healthy Living with DiabetesNational Institute of Diabetes and Digestive and Kidney Diseases
Genetics
- 17q12 deletion syndrome: MedlinePlus GeneticsNational Library of Medicine
- 6q24-related transient neonatal diabetes mellitus: MedlinePlus GeneticsNational Library of Medicine
- Congenital generalized lipodystrophy: MedlinePlus GeneticsNational Library of Medicine
- Familial partial lipodystrophy: MedlinePlus GeneticsNational Library of Medicine
- Genetics of DiabetesAmerican Diabetes Association
Statistics and Research
- Diabetes in AmericaNational Institute of Diabetes and Digestive and Kidney Diseases
- FastStats: DiabetesNational Center for Health Statistics
Clinical Trials
- ClinicalTrials.gov: Diabetes MellitusNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Diabetes Mellitus. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Diabetes, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.