Also called: Carcinoma · Malignancy · Neoplasms · Tumor
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Cancer
Cancer is not just one disease but many diseases. Cancer begins in your cells, which are the building blocks of your body. Usually, your body forms new cells as needed, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor.
Tumors can be benign or malignant. Benign tumors aren't cancer, while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of your body. The spread of cancer from one part of the body to another is called metastasis. Symptoms and treatment depend on the type of cancer and how advanced it is.
There are more than 100 different types of cancer. Cancer can start almost anywhere in your body. Most cancers are named for where they start. For example, lung cancer starts in the lung, and breast cancer starts in the breast.
Cancer may also be described by the type of cell that formed it, such as sarcoma if cancer begins in your bone and soft tissue. Carcinoma is the most common type of cancer. It is formed by epithelial cells, the cells that cover the inside and outside surfaces of your body.
Cancer is a genetic disease. That means changes in your genes cause it. Changes in your genes are also called gene variants or mutations. Genes are parts of DNA in your cells that you inherit from your parents. However, only some cancers are caused by genes passed down from your parents.
Genetic changes can occur to your genes over your lifetime that affect how your cells function. Usually, your body gets rid of damaged cells before they turn cancerous, but this ability goes down as you age. Other factors that may affect your risk of developing cancer can include:
- Exposure to ultraviolet (UV) rays from the sun
- Smoking
- Your diet
- Physical inactivity
Cancer symptoms depend on the type of cancer. For example, some of the symptoms that cancer may cause can include:
- A lump in your breast
- Blood in your urine (pee) or stool (poop)
- Bleeding or bruising for no known reason
- A sore that doesn't heal
- Trouble swallowing
- A new mole or a change to a mole you already have
Cancer may cause various symptoms but often doesn't cause pain. Don't wait until you're having pain before seeing your health care provider. See your provider if you have symptoms that don't get better in a few weeks.
There is no single test that can diagnose cancer. The tests ordered are usually based on your symptoms. Your provider may:
- Ask about your medical history
- Ask about your family health history, including relatives who have had cancer
- Do a physical exam
- Do a screening test such as a mammogram, colonoscopy, or a Pap test
- Order blood tests or imaging tests
To find out if you have cancer, your provider may order a biopsy. A biopsy is the procedure of removing and examining tissue, cells, or fluids from your body.
Treatment depends on the type of cancer and how advanced it is. Most treatment plans may include surgery, radiation, and/or chemotherapy. Some may involve hormone therapy, immunotherapy or other types of biological therapy, or stem cell transplantation.
It's usually not possible to know exactly why cancer develops in some people but not others. There are some things that you can't control which may increase or decrease your risk of getting cancer, such as inheriting certain genes or your age. But some lifestyle habits may increase your risk of certain types of cancer. Avoid or reduce lifestyle habits such as:
- Smoking and tobacco use
- Having too much sun exposure
- Drinking too much alcohol
- Not getting enough physical activity
- Having obesity
It sits within Cancers.
The lead U.S. institute for this subject is the National Cancer Institute.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Cancer
1,22,178 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or CarcinosarcomaNational Cancer Institute (NCI)
- Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)National Cancer Institute (NCI)
- Safety and Efficacy of OTL78 (Zopocianine)Clinton Bahler
- Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch RepairNational Cancer Institute (NCI)
- Physician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by SurgeryNational Cancer Institute (NCI)
- A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk RhabdomyosarcomaChildren's Oncology Group
Research already completed
- Tumor-Derived FGF19University of Central Florida
- Diabetes Prevention Program Outcomes StudyNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- 68Ga-RM2 Compared to 68Ga-PSMA-617 PET/CT for Intermediate Risk Prostate Cancer ImagingUniversity Hospital, Bordeaux
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- CancerAmerican Academy of Family Physicians
Diagnosis and Tests
- Biopsy: Types of Biopsy Procedures Used to Diagnose CancerMayo Foundation for Medical Education and Research
- Cancer Screening OverviewNational Cancer Institute
- Cancer StagingNational Cancer Institute
Treatments and Therapies
- A to Z List of Cancer DrugsNational Cancer Institute
- Adjuvant Therapy: Treatment to Keep Cancer from ReturningMayo Foundation for Medical Education and Research
- Angiogenesis InhibitorsNational Cancer Institute
- Cancer Alternative Therapies: MedlinePlus Health TopicNational Library of Medicine
- Cancer Chemotherapy: MedlinePlus Health TopicNational Library of Medicine
- Cancer Immunotherapy: MedlinePlus Health TopicNational Library of Medicine
- Cancer Surgery: Physically Removing CancerMayo Foundation for Medical Education and Research
- Carcinoma of Unknown Primary TreatmentNational Cancer Institute
Prevention and Risk Factors
- Antioxidants and Cancer PreventionNational Cancer Institute
- Cancer Prevention OverviewNational Cancer Institute
Living With
- Cancer--Living with Cancer: MedlinePlus Health TopicNational Library of Medicine
Related Issues
- Adjusting to CancerNational Cancer Institute
- Cancer Causes: Popular Myths about the Causes of CancerMayo Foundation for Medical Education and Research
- Cancer ClustersNational Cancer Institute
Genetics
- BAP1 tumor predisposition syndrome: MedlinePlus GeneticsNational Library of Medicine
- Bloom syndrome: MedlinePlus GeneticsNational Library of Medicine
Statistics and Research
- About Cancer Clinical ResearchNational Cancer Institute
- Cancer Clinical Trials at the National Institutes of Health Clinical CenterNational Cancer Institute
- Cancer Data and StatisticsCenters for Disease Control and Prevention
- Cancer StatisticsNational Cancer Institute
Medical subject headings
Clinicians and researchers index this subject under Neoplasms. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Cancer, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.