Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Cancer Chemotherapy
Cancer chemotherapy is a type of cancer treatment. It uses medicines to destroy cancer cells.
Normally, your body forms new cells as needed, replacing old cells that die. Cancer cells keep growing without control. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Chemotherapy works by killing the cancer cells, stopping them from spreading, or slowing their growth.
Chemotherapy is used to:
- Treat cancer by curing the cancer, lessening the chance it will return, or stopping or slowing its growth.
- Ease cancer symptoms by shrinking tumors that are causing pain and other problems.
Chemotherapy does not just destroy cancer cells. It can also harm some healthy cells, which causes side effects.
You may have a lot of side effects, some side effects, or none at all. It depends on the type and amount of chemotherapy you get and how your body reacts.
Some common side effects are:
- Mouth sores
- Fatigue
- Nausea and vomiting
- Pain
- Hair loss
There are ways to prevent or control some side effects. Talk with your health care provider about how to manage them. Healthy cells usually recover after chemotherapy is over, so most side effects go away over time.
You may get chemotherapy in a hospital, at home, at your provider's office, or a medical clinic. You might be given the medicines by mouth, in a shot, as a cream, through a catheter (a thin tube), or intravenously (by IV).
Your treatment plan will depend on the type of cancer you have, which chemotherapy medicines are used, the treatment goals, and how your body responds to the medicines.
Chemotherapy may be given alone or with other treatments. You may get treatment every day, every week, or every month. You may have breaks between treatments so that your body has a chance to build new healthy cells.
It sits within Cancers and Drug Therapy.
The lead U.S. institute for this subject is the National Cancer Institute.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Cancer Chemotherapy
16,512 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or CarcinosarcomaNational Cancer Institute (NCI)
- Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch RepairNational Cancer Institute (NCI)
- A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk RhabdomyosarcomaChildren's Oncology Group
- Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk NeuroblastomaNational Cancer Institute (NCI)
- Impact of Probiotics on Neuropathy Induced by Adjuvant Chemotherapy in Patients With Colon Cancer.Centre Francois Baclesse
- Phase II Study of CD5 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Aggressive T Cell Hematological MalignanciesM.D. Anderson Cancer Center
Research already completed
- NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid TumorsNational Cancer Institute (NCI)
- Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell TransplantM.D. Anderson Cancer Center
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- A to Z List of Cancer DrugsNational Cancer Institute
- ChemotherapyAmerican Cancer Society
- Chemotherapy and You: Support for People with CancerNational Cancer Institute
- Chemotherapy to Treat CancerNational Cancer Institute
Living With
- Eating Hints: Before, during, and after Cancer TreatmentNational Cancer Institute
Related Issues
- Anemia: Cancer Treatment Side EffectNational Cancer Institute
- Bleeding and Bruising (Thrombocytopenia) and Cancer TreatmentNational Cancer Institute
- Cancer FatigueNational Cancer Institute
- Cancer Therapy Interactions with Foods and Dietary SupplementsNational Cancer Institute
- Cancer Treatments & Oral HealthNational Institute of Dental and Craniofacial Research
- Chemo BrainMayo Foundation for Medical Education and Research
- Chemotherapy and Hair Loss: What to Expect during TreatmentMayo Foundation for Medical Education and Research
- Chemotherapy and Sex: Is Sexual Activity OK during Treatment?Mayo Foundation for Medical Education and Research
- Chemotherapy Side Effects: A Cause of Heart Disease?Mayo Foundation for Medical Education and Research
- Constipation and Cancer TreatmentNational Cancer Institute
- Diarrhea and Cancer TreatmentNational Cancer Institute
- Edema (Swelling) and Cancer TreatmentNational Cancer Institute
- Hair Loss (Alopecia) and Cancer TreatmentNational Cancer Institute
- Infection and Neutropenia during Cancer TreatmentNational Cancer Institute
- Low Blood Cell Counts: Side Effects of Cancer TreatmentMayo Foundation for Medical Education and Research
- Managing Cancer-Related Side EffectsAmerican Cancer Society
- Memory or Concentration Problems and Cancer TreatmentNational Cancer Institute
Statistics and Research
- Cholesterol Drug May Help Protect the Heart during Chemotherapy for LymphomaNational Cancer Institute
Clinical Trials
- ClinicalTrials.gov: Cancer ChemotherapyNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Antineoplastic Agents, Neoplasms. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Cancer Chemotherapy, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.