Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Cancer Immunotherapy
Immunotherapy is a cancer treatment that helps your immune system fight cancer. It is a type of biological therapy. Biological therapy uses substances made from living organisms or versions of these substances made in a lab. Immunotherapy isn't used for all cancers, and the response to treatment varies. If you're getting immunotherapy, your health care provider will monitor your treatment closely.
Immunotherapy isn't used as often as other cancer treatments, such as surgery, chemotherapy, and radiation therapy. But immunotherapy is used for some types of cancer, and researchers are doing clinical trials to see whether it also works for other types.
Cancer begins in your cells, which are the building blocks of your body. Usually, your body forms new cells as needed, replacing old cells that die. Sometimes, this process goes wrong. When you have cancer, some of your cells begin to multiply without stopping, and old cells don't die when they should. They spread into the surrounding tissues.
One reason cancer cells can keep growing and spreading is that they can hide from your immune system. Some immunotherapies can "mark" your cancer cells. This makes it easier for your immune system to find and destroy the cells. It is a type of targeted therapy that uses medicines or other substances that attack specific cancer cells with less harm to normal cells. Other types of immunotherapies work by boosting your immune system to work better against cancer.
There are different forms of immunotherapy, so how they are given varies. You could get immunotherapy intravenously (by IV), in pills or capsules, or cream for your skin. For bladder cancer, they might place it directly into your bladder.
How often and how long you get immunotherapy also varies. It depends on your type of cancer, how advanced it is, the type of immunotherapy you get, and how well it is working. You may have treatment every day, week, or month. Some immunotherapies are given in cycles, so your body has time to rest and recover.
You may have side effects. The most common side effects are skin reactions at the needle site if you get it by IV. Other side effects may include flu-like symptoms or, rarely, severe reactions.
It sits within Cancers.
The lead U.S. institute for this subject is the National Cancer Institute.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Cancer Immunotherapy
4,429 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- To Explore a Single-arm Phase II Study on Intestinal Microbiota Transplantation Combined With Neoadjuvant Immunotherapy and Chemoradiotherapy for Locally Advanced Rectal Cancer Under MSS/pMMRTianjin Medical University Cancer Institute and Hospital
- Anti-CRLF2-R/TSLPR Chimeric Antigen Receptor T Cells (TSLPR-CART) in Participants With Recurrent or Refractory CRLF2-R/TSLPR-Overexpressing B-Cell Acute Lymphoblastic Leukemia (B-ALL)National Cancer Institute (NCI)
- Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic MalignanciesNational Cancer Institute (NCI)
- Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)National Cancer Institute (NCI)
- Study of PM54 in Combination With Immunotherapy in Adult Participants With Advanced MalignanciesPharmaMar
- Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT TrialNational Cancer Institute (NCI)
Research already completed
- NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid TumorsNational Cancer Institute (NCI)
- Intestinal Low Dose Radiotherapy Combined With Immunotherapy in Immune-resistant Metastatic Solid TumorsChuangzhen Chen
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Learn More
- ImmunotherapyBlood Cancer United
- ImmunotherapyAmerican Cancer Society
- Immunotherapy to Treat CancerNational Cancer Institute
- Immunotherapy: questions to ask your doctorMedical Encyclopedia
- Monoclonal AntibodiesNational Cancer Institute
- Off-Label Drug Use in Cancer TreatmentNational Cancer Institute
- PDL1 (Immunotherapy) TestsNational Library of Medicine
- Radioimmunotherapy (RIT)Radiological Society of North America
Clinical Trials
- ClinicalTrials.gov: Cancer ImmunotherapyNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Neoplasms, Immunotherapy. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Cancer Immunotherapy, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.