Also called: Brachytherapy · Radiotherapy
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Radiation Therapy
Radiation therapy is a cancer treatment. It uses high doses of radiation to kill cancer cells and stop them from spreading. It may also be used for easing cancer symptoms. Radiation therapy may damage healthy cells. They can usually repair themselves more easily than cancer cells.
You may need days or weeks of treatment before the radiation starts killing cancer cells. But cancer cells should keep dying for weeks or months after your treatment ends.
Radiation therapy treats many types of cancer. It may be used at different times or for different reasons during your treatment. Sometimes radiation is used with other treatments, like surgery, chemotherapy, or immunotherapy.
You may get radiation therapy once a day or in smaller doses twice a day for a few weeks. The radiation may be external, from special machines, or internal from radioactive substances placed inside your body.
The type of radiation therapy you get depends on many factors, including:
- The type of cancer
- The size of the cancer
- Where the cancer is in your body
- How close the cancer is to normal tissues that are sensitive to radiation
- How far the radiation needs to travel into your body
- Your general health and medical history
- Whether you will have other types of cancer treatment
- Other factors, such as your age and other medical conditions
Your treatment must be carefully planned to reduce side effects. Radiation therapy can damage normal cells as well as cancer cells. Healthy cells usually repair themselves but damaging them can cause side effects.
Side effects can vary from person to person. Common side effects include skin changes and fatigue. Other side effects depend on the part of your body being treated. Most side effects go away a few months after you are done with treatment.
It sits within Cancers and Surgery and Rehabilitation.
The lead U.S. institute for this subject is the National Cancer Institute.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Radiation Therapy
8,808 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Phase 1 Clinical Trial of Lenvatinib, Pembrolizumab and Hypofractionated Pelvic Radiation Therapy for pMMR Recurrent/Unresectable Endometrial CarcinomaAaron Wolfson
- A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)National Cancer Institute (NCI)
- Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic CancerNational Cancer Institute (NCI)
- Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung CancerNational Cancer Institute (NCI)
- Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care RadiationM.D. Anderson Cancer Center
- Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell CarcinomaNational Cancer Institute (NCI)
Research already completed
- Neuropsychological Changes in Patients Receiving Radiation Therapy for Brain MetastasesNational Cancer Institute (NCI)
- Intestinal Low Dose Radiotherapy Combined With Immunotherapy in Immune-resistant Metastatic Solid TumorsChuangzhen Chen
- Safety and Efficacy of Fluoroscopy-free Technique During Retrograde Intrarenal Surgery for Renal StonesAl-Azhar University
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Radiation Therapy and You: Support for People with CancerNational Cancer Institute
- Radiation Therapy to Treat CancerNational Cancer Institute
- What Goes into Planning Your Radiation TherapyAmerican Cancer Society
Related Issues
- Frequent Questions: Radiation in MedicineEnvironmental Protection Agency
- Low Blood Cell Counts: Side Effects of Cancer TreatmentMayo Foundation for Medical Education and Research
- Oral Complications of Cancer TherapiesNational Cancer Institute
- Radiation Therapy Side EffectsAmerican Cancer Society
Clinical Trials
- ClinicalTrials.gov: RadiotherapyNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Radiotherapy. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Radiation Therapy, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.