Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Prediabetes
Prediabetes means that your blood glucose, or blood sugar, levels are higher than normal but not high enough to be called diabetes. Glucose comes from the foods you eat. Too much glucose in your blood can damage your body over time.
If you have prediabetes, you are more likely to develop type 2 diabetes, heart disease, and stroke. But if you make some lifestyle changes now, you may be able to delay or prevent type 2 diabetes.
Prediabetes usually happens when your body has a problem with insulin. Insulin is a hormone that helps the glucose get into your cells to give them energy. A problem with insulin could be:
- Insulin resistance, a condition in which the body can't use its insulin properly. It makes it hard for your cells to get glucose from your blood. This can cause your blood sugar levels to rise.
- Your body can't make enough insulin to keep your blood sugar levels at a healthy level
Researchers think that being overweight and not getting regular physical activity are major factors in causing prediabetes.
About 1 out of every 3 adults has prediabetes. It is more common in people who:
- Are overweight or have obesity
- Are age 45 or older
- Have a parent, brother, or sister with diabetes
- Are African American, Alaska Native, American Indian, Asian American, Hispanic/Latino, Native Hawaiian, or Pacific Islander American
- Are not physically active
- Have health conditions such as high blood pressure and high cholesterol
- Have had gestational diabetes (diabetes in pregnancy)
- Have a history of heart disease or stroke
- Have metabolic syndrome
- Have polycystic ovary syndrome (PCOS)
Most people don't know they have prediabetes because usually there are no symptoms.
Some people with prediabetes may have darkened skin in the armpit or on the back and sides of the neck. They may also have many small skin growths in those same areas.
There are a few different blood tests that can diagnose prediabetes. The most common ones are:
- Fasting plasma glucose (FPG) test, which measures your blood sugar at a single point in time. You need to fast (not eat or drink) for at least 8 hours before the test. The results of the test are given in mg/dL (milligrams per deciliter): A normal level is 99 or below
- Prediabetes is 100 to 125
- Type 2 diabetes is 126 and above
- A normal level is below 5.7%
- Prediabetes is between 5.7 to 6.4%
- Type 2 diabetes is above 6.5%
If you have prediabetes, you may be able to delay or prevent type 2 diabetes through lifestyle changes:
- Losing weight, if you are overweight
- Getting regular physical activity
- Following a healthy, reduced-calorie eating plan
In some cases, your health care provider may also recommend taking diabetes medicines.
If you are at risk for prediabetes, those same lifestyle changes (losing weight, regular physical activity, and a healthy eating plan) may prevent you from getting it.
It sits within Endocrine System and Diabetes Mellitus.
The lead U.S. institute for this subject is the National Institute of Diabetes and Digestive and Kidney Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Prediabetes
1,711 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Blood-based sEV Proteins for Early Detection of 2 DiabetesHong Kong Baptist University
- AIM-WEIGHT: AI-Guided Microbiome-Targeted Nutritional Intervention for Weight LossVarol TUNALI
- Xinqiao High-risk Cohort of Diabetes(NICE)Shanghai General Hospital, China
- Point-of-care Capillary HbA1c Testing for Type 2 Diabetes Screening Among At-risk Individuals in Rural Dali, ChinaThe University of Hong Kong
- Time-Restricted Eating and Staple Food Reduction Combined With App-Supported Exercise for Weight and Glycemic ControlPeking University
- The Effectiveness of Smoking Cessation in Prediabetic SmokersNational Taiwan University Hospital
Research already completed
- Diabetes Prevention Program Outcomes StudyNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- The Influence of Time-Restricted Eating in Patients With Metabolic SyndromeUniversity of California, San Diego
- mHealth Intervention to Increase Physical Activity in Prediabetes and Type 2 DiabetesCharles University, Czech Republic
- Personalized Meal Timing and Walking Based on Glucose Patterns in Adults With PrediabetesShifa International Hospital
- The Effects of Intermittent Fasting on Anthropometric Measurements and Metabolic Parameters in Prediabetic PatientsAtaturk University
- Effect of a Collagen Hydrolysate on Postprandial Blood Glucose Profile in Prediabetic and Healthy SubjectsRousselot BVBA
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- About PrediabetesAmerican Heart Association
- PrediabetesAmerican Academy of Family Physicians
- Prediabetes -- Your Chance to Prevent Type 2 DiabetesCenters for Disease Control and Prevention
Diagnosis and Tests
- A1C: MedlinePlus Health TopicNational Library of Medicine
- Blood Glucose TestNational Library of Medicine
- Diabetes Diagnosis and TestsAmerican Diabetes Association
- Diabetes TestsNational Library of Medicine
- Diabetes Tests and DiagnosisNational Institute of Diabetes and Digestive and Kidney Diseases
Treatments and Therapies
- Prediabetes DietJohns Hopkins Medicine
Prevention and Risk Factors
- Diabetes Risk FactorsAmerican Heart Association
- Surprising Truth about PrediabetesCenters for Disease Control and Prevention
- Weight Management to Prevent or Reverse PrediabetesCenters for Disease Control and Prevention
Living With
- How to Prevent Diabetes: MedlinePlus Health TopicNational Library of Medicine
Related Issues
- All about Insulin ResistanceAmerican Diabetes Association
- Diabetes Complications and RisksAmerican Heart Association
- Diabetes, Heart Disease, and StrokeNational Institute of Diabetes and Digestive and Kidney Diseases
- Insulin Resistance and PrediabetesNational Institute of Diabetes and Digestive and Kidney Diseases
Statistics and Research
- Prediabetes in US AdolescentsCenters for Disease Control and Prevention
Clinical Trials
- ClinicalTrials.gov: Insulin ResistanceNational Institutes of Health
- ClinicalTrials.gov: Prediabetic StateNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Prediabetic State. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Prediabetes, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.