Also called: Type 2 Diabetes
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Diabetes Type 2
Type 2 diabetes is a disease in which your blood glucose, or blood sugar, levels are too high. Glucose is your main source of energy. It comes from the foods you eat. A hormone called insulin helps the glucose get into your cells to give them energy. If you have diabetes, your body doesn't make enough insulin or doesn't use insulin well. The glucose then stays in your blood and not enough goes into your cells.
Over time, having too much glucose in your blood can cause health problems. But you can take steps to manage your diabetes and try to prevent these health problems.
Type 2 diabetes may be caused by a combination of factors:
- Being overweight or having obesity
- Not being physically active
- Genetics and family history
Type 2 diabetes usually starts with insulin resistance. This is a condition in which your cells don't respond normally to insulin. As a result, your body needs more insulin to help the glucose enter your cells. At first, your body makes more insulin to try to get cells to respond. But over time, your body can't make enough insulin, and your blood glucose levels rise.
You are at higher risk of developing type 2 diabetes if you:
- Are over age 45. Children, teenagers, and younger adults can get type 2 diabetes, but it is more common in middle-aged and older people.
- Have prediabetes, which means that your blood glucose is high for you but not high enough to be called diabetes
- Had diabetes in pregnancy or gave birth to a baby weighing 9 pounds or more.
- Have a family history of diabetes
- Are overweight or have obesity
- Are Black or African American, Hispanic/Latino, American Indian, Asian American, or Pacific Islander
- Are not physically active
- Have other conditions such as high blood pressure, heart disease, stroke, polycystic ovary syndrome (PCOS), or depression
- Have low HDL (good) cholesterol and high triglycerides
- Have acanthosis nigricans - dark, thick, and velvety skin around your neck or armpits
Many people with type 2 diabetes have no symptoms at all. If you do have them, the symptoms develop slowly over several years. They might be so mild that you do not notice them. The symptoms can include:
- Increased thirst and urination
- Increased hunger
- Feeling tired
- Blurred vision
- Numbness or tingling in the feet or hands
- Sores that do not heal
- Unexplained weight loss
Your provider will use blood tests to diagnose type 2 diabetes. The blood tests include:
- A1C test, which measures your average blood glucose level over the past 3 months.
- Fasting plasma glucose (FPG) test, which measures your current blood glucose level. You need to fast (not eat or drink anything except water) for at least 8 hours before the test.
- Random plasma glucose (RPG) test, which measures your current blood glucose level. This test is used when you have diabetes symptoms and the provider does not want to wait for you to fast before having the test.
Treatment for type 2 diabetes involves managing your blood glucose levels. Many people are able to do this by living a healthy lifestyle. Some people may also need to take medicine:
- A healthy lifestyle includes following a healthy eating plan and getting regular physical activity. You need to learn how to balance what you eat and drink with physical activity and diabetes medicine, if you take any.
- Medicines for diabetes include oral medicines, insulin, and other injectable medicines. Over time, some people will need to take more than one type of medicine to control their diabetes.
- You will need to check your blood glucose regularly. Your provider will tell you how often you need to do it.
- It's also important to keep your blood pressure and cholesterol levels close to the targets your provider sets for you. Make sure to get your screening tests regularly.
You can take steps to help prevent or delay type 2 diabetes by losing weight if you are overweight, eating fewer calories, and being more physically active. If you have a condition which raises your risk for type 2 diabetes, managing that condition may lower your risk of getting type 2 diabetes.
It sits within Endocrine System and Diabetes Mellitus.
The lead U.S. institute for this subject is the National Institute of Diabetes and Digestive and Kidney Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Diabetes Type 2
11,818 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Advancing Diabetes Management for People With Physical Disabilities Optimally Through Primary Care-Based Telehealth (ADDOPT)University of Alabama at Birmingham
- A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightNovo Nordisk A/S
- Relationship Between Red Cell Distribution Width (RDW) and HbA1C in Patients With Type 2 Diabetes Mellitus After Glycemic ControlNew Valley University
- Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic CancerAulos Bioscience, Inc.
- Integrating New Skills Into Diabetes Education With CGMUniversity of North Carolina, Chapel Hill
- Blood-based sEV Proteins for Early Detection of 2 DiabetesHong Kong Baptist University
Research already completed
- Diabetes Prevention Program Outcomes StudyNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or OverweightEli Lilly and Company
- DIA:CONN P8(Smart Insulin Pen) Study in Diabetes PatientsG2e Co., Ltd
- A Study of HRS9531 Versus Semaglutide Once Weekly as Add-on Therapy to Metformin Monotherapy or in Combination With SGLT2 Inhibitors in Participants With Type 2 DiabetesFujian Shengdi Pharmaceutical Co., Ltd.
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Diagnosis and Tests
- A1C: MedlinePlus Health TopicNational Library of Medicine
- Diabetes TestsNational Library of Medicine
- Diabetes Tests and DiagnosisNational Institute of Diabetes and Digestive and Kidney Diseases
- Insulin in BloodNational Library of Medicine
- Ketones in BloodNational Library of Medicine
- Ketones in UrineNational Library of Medicine
Treatments and Therapies
- Diabetes and Dietary Supplements: What You Need to KnowNational Center for Complementary and Integrative Health
- Diabetes Medicines: MedlinePlus Health TopicNational Library of Medicine
Prevention and Risk Factors
- Find a Lifestyle Change ProgramCenters for Disease Control and Prevention
- How to Prevent Diabetes: MedlinePlus Health TopicNational Library of Medicine
Living With
- Changing Your Habits for Better HealthNational Institute of Diabetes and Digestive and Kidney Diseases
- Diabetes and Mental HealthCenters for Disease Control and Prevention
- Diabetic Diet: MedlinePlus Health TopicNational Library of Medicine
- Healthy WeightCenters for Disease Control and Prevention
- How to Stay Healthy With Type 2 DiabetesNemours Foundation
- Managing DiabetesNational Institute of Diabetes and Digestive and Kidney Diseases
Related Issues
- 5 Things To Know About Type 2 Diabetes and Dietary SupplementsNational Center for Complementary and Integrative Health
- Acanthosis NigricansMayo Foundation for Medical Education and Research
- Health Consequences of Early Exposure to SugarNational Institutes of Health
- Healthy Living with DiabetesNational Institute of Diabetes and Digestive and Kidney Diseases
Genetics
- Genetics of DiabetesAmerican Diabetes Association
Statistics and Research
- Diabetes Drug May Reduce Colorectal Cancer RiskNational Institutes of Health
- Diabetes in AmericaNational Institute of Diabetes and Digestive and Kidney Diseases
Clinical Trials
- ClinicalTrials.gov: Diabetes Mellitus, Type 2National Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Diabetes Mellitus, Type 2. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Diabetes Type 2, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.