Also called: Hepatic diseases
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Liver Diseases
Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons.
There are many kinds of liver diseases:
- Diseases caused by viruses, such as hepatitis A, hepatitis B, and hepatitis C.
- Diseases caused by drugs, poisons, or too much alcohol. Examples include steatotic liver disease and cirrhosis.
- Liver cancer.
- Inherited diseases, such as hemochromatosis and Wilson disease.
Symptoms of liver disease can vary, but they often include swelling of the abdomen and legs, bruising easily, changes in the color of your stool and urine, and jaundice, or yellowing of the skin and eyes. Sometimes there are no symptoms. Tests such as imaging tests and liver function tests can check for liver damage and help to diagnose liver diseases.
It sits within Digestive System.
The lead U.S. institute for this subject is the National Institute of Diabetes and Digestive and Kidney Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Liver Diseases
14,939 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)National Cancer Institute (NCI)
- Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta VirusGilead Sciences
- Prevalence and Development of Liver Dysfunction in Hematopoietic Stem Cell TransplantNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIVNaga P. Chalasani
- Hepatic Lipid Metabolism-Alcohol Use DisorderNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors With Statin for ACS PatientsAssiut University
Research already completed
- Phase 2a Study to Evaluate Safety and Explore Efficacy of J2H-1702 for NASHJ2H Biotech
- Effectiveness and Safety of Probiotics in Protecting Liver FunctionWecare Probiotics Co., Ltd.
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Diagnosis and Tests
- Abdominal and Pelvic CTRadiological Society of North America
- Abdominal UltrasoundRadiological Society of North America
- Body MRIRadiological Society of North America
- Chloride Blood TestNational Library of Medicine
- ElastographyNational Library of Medicine
- Endoscopic Retrograde Cholangiopancreatography (ERCP)National Institute of Diabetes and Digestive and Kidney Diseases
- Gamma-glutamyl Transferase (GGT) TestNational Library of Medicine
Prevention and Risk Factors
- 25 Ways to Love Your Liver HealthAmerican Liver Foundation
- Fighting Fatty Liver: Steps Against a Silent DiseaseNational Institutes of Health
Related Issues
- Cirrhosis and Portal HypertensionAmerican Academy of Family Physicians
Genetics
- Alagille syndrome: MedlinePlus GeneticsNational Library of Medicine
- Alpers-Huttenlocher syndrome: MedlinePlus GeneticsNational Library of Medicine
- Benign recurrent intrahepatic cholestasis: MedlinePlus GeneticsNational Library of Medicine
- Childhood myocerebrohepatopathy spectrum: MedlinePlus GeneticsNational Library of Medicine
- Congenital bile acid synthesis defect type 2: MedlinePlus GeneticsNational Library of Medicine
- Congenital generalized lipodystrophy: MedlinePlus GeneticsNational Library of Medicine
- Congenital hepatic fibrosis: MedlinePlus GeneticsNational Library of Medicine
- Crigler-Najjar syndrome: MedlinePlus GeneticsNational Library of Medicine
- Gilbert syndrome: MedlinePlus GeneticsNational Library of Medicine
- Glycogen storage disease type III: MedlinePlus GeneticsNational Library of Medicine
- Glycogen storage disease type VI: MedlinePlus GeneticsNational Library of Medicine
Statistics and Research
- FastStats: Chronic Liver Disease and CirrhosisNational Center for Health Statistics
Clinical Trials
- ClinicalTrials.gov: Alagille SyndromeNational Institutes of Health
- ClinicalTrials.gov: Liver DiseasesNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Liver Diseases. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Liver Diseases, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.