Health Topic

Hepatitis C

Hepatitis C (HCV) is virus that causes liver inflammation. It usually spreads through contact with blood from someone who has HCV. It can be acute or chronic.

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Also called: HCV

Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.

About Hepatitis C

Hepatitis is inflammation of the liver. Inflammation is swelling that happens when tissues of the body are injured or infected. Inflammation can damage organs.

There are different types of hepatitis. One type, hepatitis C, is caused by the hepatitis C virus (HCV). Hepatitis C can range from a mild illness lasting a few weeks to a serious, lifelong illness.

Hepatitis C can be acute or chronic:

  • Acute hepatitis C is a short-term infection. The symptoms can last up to 6 months. Sometimes your body is able to fight off the infection and the virus goes away. But for most people, an acute infection leads to chronic infection.
  • Chronic hepatitis C is a long-lasting infection. If it is not treated, it can last for a lifetime and cause serious health problems, including liver damage, cirrhosis (scarring of the liver), liver cancer, and even death.

Hepatitis C spreads through contact with the blood of someone who has HCV. This contact may be through:

  • Sharing drug needles or other drug materials with someone who has HCV. In the United States, this is the most common way that people get hepatitis C.
  • Getting an accidental stick with a needle that was used on someone who has HCV. This can happen in health care settings.
  • Being tattooed or pierced with tools or inks that were not sterilized after being used on someone who has HCV.
  • Having contact with the blood or open sores of someone who has HCV.
  • Sharing personal care items that may have come in contact with another person's blood, such as razors or toothbrushes.
  • Being born to a mother with HCV.
  • Having unprotected sex with someone who has HCV.

Before 1992, hepatitis C was also commonly spread through blood transfusions and organ transplants. Since then, there has been routine testing of the U.S. blood supply for HCV. It is now very rare for someone to get HCV this way.

You are more likely to get hepatitis C if you:

  • Have injected drugs
  • Had a blood transfusion or organ transplant before July 1992
  • Have hemophilia and received clotting factor before 1987
  • Have been on kidney dialysis
  • Have been in contact with blood or infected needles at work
  • Have had tattoos or body piercings
  • Have worked or lived in a prison
  • Were born to a mother with hepatitis C
  • Have HIV
  • Have had more than one sex partner in the last 6 months
  • Have had a sexually transmitted infection (STI)
  • Are a man who has had sex with men (MSM)

If you are at high risk for hepatitis C, your health care provider will likely recommend that you get tested for it.

Most people with hepatitis C have no symptoms. Some people with acute hepatitis C do have symptoms within 1 to 3 months after they are exposed to the virus. These symptoms may include:

  • Dark yellow urine
  • Fatigue
  • Fever
  • Gray- or clay-colored stools
  • Joint pain
  • Loss of appetite
  • Nausea and/or vomiting
  • Pain in your abdomen (belly)
  • Jaundice (yellowish eyes and skin)

If you have chronic hepatitis C, you probably will not have symptoms until it causes complications. This can happen decades after you were infected. For this reason, hepatitis C screening is important, even if you have no symptoms.

Without treatment, hepatitis C may lead to cirrhosis, liver failure, and liver cancer. Early diagnosis and treatment of hepatitis C can prevent these complications.

Providers diagnose hepatitis C based on your medical history, a physical exam, and blood tests.

If you do have hepatitis C, you may need additional tests to check for liver damage. These tests may include other blood tests, an ultrasound of the liver, and a liver biopsy.

Treatment for hepatitis C is with antiviral medicines. They can cure the disease in most cases.

If you have acute hepatitis C, your provider may wait to see if your infection becomes chronic before starting treatment.

If your hepatitis C causes cirrhosis, you should see a doctor who specializes in liver diseases. Treatments for health problems related to cirrhosis include medicines, surgery, and other medical procedures. If your hepatitis C leads to liver failure or liver cancer, you may need a liver transplant.

There is no vaccine for hepatitis C. But you can help protect yourself from hepatitis C infection by:

  • Not sharing drug needles or other drug materials.
  • Wearing gloves if you have to touch another person's blood or open sores.
  • Making sure your tattoo artist or body piercer uses sterile tools and unopened ink.
  • Not sharing personal items such toothbrushes, razors, or nail clippers.
  • Using a latex condom during sex. If your or your partner is allergic to latex, you can use polyurethane condoms.

It sits within Digestive System and Infections.

The lead U.S. institute for this subject is the National Institute of Diabetes and Digestive and Kidney Diseases.

When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.

Research on Hepatitis C

2,564 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.

What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.

Research currently under way

Research already completed

Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.

Where to read more

Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.

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Diagnosis and Tests

Treatments and Therapies

Prevention and Risk Factors

Living With

Related Issues

Statistics and Research

Clinical Trials

Medical subject headings

Clinicians and researchers index this subject under Hepatitis C. These are the terms to use when searching medical literature.

This page is built from the MedlinePlus health topic record for Hepatitis C, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.