Also called: Diabetic retinopathy
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Diabetic Eye Problems
Diabetes is a disease in which your blood glucose, or blood sugar, levels are too high. Glucose comes from foods you eat. The cells of your body need glucose for energy. A hormone called insulin helps the glucose get into your cells.
With type 1 diabetes, your body doesn't make insulin. With type 2 diabetes, your body doesn't make or use insulin well. Without enough insulin, glucose builds up in your blood and causes high blood glucose levels.
Over time, high blood glucose may damage the blood vessels and lenses in your eyes. This can lead to serious diabetic eye problems which can harm your vision and sometimes cause blindness. Some common diabetic eye problems include:
- Diabetic retinopathy, which is the leading cause of blindness in American adults. It affects blood vessels in the retina (the light-sensitive layer of tissue in the back of your eye). The blood vessels may swell and leak fluid into your eye. If it's not treated, it can cause serious problems such as vision loss and retinal detachment, where the retina is pulled away from its normal position at the back of your eye.
- Diabetic macular edema (DME), which happens when blood vessels in the retina leak fluid into the macula (the part of the retina needed for sharp, central vision). This usually develops in people who already have other signs of diabetic retinopathy.
- Glaucoma, a group of eye diseases that can damage the optic nerve (the bundle of nerves that connects the eye to the brain). Glaucoma from diabetes happens when the blood vessels in the front of your eye are damaged, and new blood vessels grow near the iris (the colored part of your eye). The blood vessels block the space where fluid drains from your eye. This causes fluid to build up and pressure to increase inside your eye.
- Cataract, which is the leading cause of blindness worldwide. It happens when the clear lens in the front of your eye becomes cloudy. Cataracts are common as people age. But people with diabetes are more likely to develop cataracts younger and faster than people without diabetes. Researchers think that high glucose levels cause deposits to build up in the lenses of your eyes.
Anyone with diabetes can develop diabetic eye disease. But your risk of developing it is higher if you have diabetes and:
- Have had diabetes for a long time
- Don't have good control over your high blood glucose or high blood pressure
- Are pregnant
- Have high blood cholesterol
- Smoke tobacco
In the early stages, diabetic eye problems usually don't have any symptoms. That's why regular dilated eye exams are so important, even if you think your eyes are healthy.
You should also watch for sudden changes in your vision that could be signs of an emergency. Call your eye care professional right away if you notice any of these symptoms:
- Many new spots or dark wavy strings floating in your vision (floaters)
- Flashes of light
- A dark shadow over part of your vision, like a curtain
- Vision loss
- Eye pain or redness
Talk with your eye care professional if you have these symptoms, even if they come and go:
- Spots or dark wavy strings floating in your vision
- Blurry or wavy vision
- Vision that changes a lot
- Trouble seeing colors
Eye care professionals do dilated eye exams to diagnose eye problems. A dilated eye exam uses eye drops to open your pupils wide so your eye care professional can look for signs of eye problems and treat them before they harm your vision. They will also test your vision and measure the pressure in your eyes.
Treatment for diabetic eye problems depends on the problem and how serious it is. Some of the treatments include:
- Lasers to stop blood vessels from leaking
- Injections (shots) in the eye to stop new, leaky blood vessels from growing
- Surgery to remove blood and scar tissue or replace a cloudy lens
- Eye drops to lower fluid pressure in the eye
But these treatments aren't cures. Eye problems can come back. That's why your best defense against serious vision loss is to take control of your diabetes and get regular eye exams. It's also important to keep your blood pressure and cholesterol in a healthy range.
It sits within Eyes and Vision, Endocrine System and Diabetes Mellitus.
The lead U.S. institute for this subject is the National Eye Institute.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Diabetic Eye Problems
28 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 DiabetesNovo Nordisk A/S
- Implementing Artificial Intelligence to Prevent Vision Loss From DiabetesUniversity of Wisconsin, Madison
- Leveraging Artificial Intelligence to Prevent Vision Loss From DiabetesUniversity of Wisconsin, Madison
- Is Community Based Monitoring of Diabetic Maculopathy and Pre-proliferative Diabetic Retinopathy Safe?Hywel Dda Health Board
- Long-Term Follow-up Study of ADVM-022 in DME (INFINITY-EXT)Adverum Biotechnologies, Inc.
Research already completed
- A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Diabetic Retinopathy (DR)Kodiak Sciences Inc
- Study of a High-Dose Aflibercept in Participants With Diabetic Eye DiseaseRegeneron Pharmaceuticals
- Diquafosol vs Hyaluronic Acid for Diabetic Dry EyeHe Eye Hospital
- ADVM-022 Intravitreal Gene Therapy for DMEAdverum Biotechnologies, Inc.
- Detection and Classification of Diabetic Retinopathy From Posterior Pole Images With A Deep Learning ModelUral Telekomunikasyon Sanayi Ticaret Anonim Sirketi
- HORNBILL: A Study to Test Different Doses of BI 764524 in Patients Who Have Had Laser Treatment for a Type of Diabetic Eye Disease Called Diabetic Retinopathy With Diabetic Macular IschemiaBoehringer Ingelheim
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Diabetic Eye DiseaseNational Institute of Diabetes and Digestive and Kidney Diseases
- Diabetic RetinopathyNational Eye Institute
- Diabetic Retinopathy: Causes, Symptoms, TreatmentAmerican Academy of Ophthalmology
- Eye ComplicationsAmerican Diabetes Association
Symptoms
- Eye SymptomsAmerican Academy of Ophthalmology
Diagnosis and Tests
- Dilating Eye DropsAmerican Association for Pediatric Ophthalmology and Strabismus
- Eye Exam and Vision Testing BasicsAmerican Academy of Ophthalmology
Prevention and Risk Factors
- Eye Care: MedlinePlus Health TopicNational Library of Medicine
- Stay on TRACK to Prevent Blindness from DiabetesNational Eye Institute
Related Issues
- Talking with Your Eye DoctorNational Eye Institute
- What Is Macular Edema?American Academy of Ophthalmology
Statistics and Research
- Eye Health Data and StatisticsNational Eye Institute
- NEI-Funded Study Shows Low Blood Sugar Contributes to Eye Damage and Vision Loss in Diabetic RetinopathyNational Eye Institute
Clinical Trials
- ClinicalTrials.gov: Diabetic RetinopathyNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Diabetic Retinopathy. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Diabetic Eye Problems, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.