Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Testicular Disorders
Testicles, or testes, make male hormones and sperm. They are two egg-shaped organs inside the scrotum, the loose sac of skin behind the penis. It's easy to injure your testicles because they are not protected by bones or muscles. Men and boys should wear athletic supporters when they play sports.
You should examine your testicles monthly and seek medical attention for lumps, redness, pain or other changes. Testicles can get inflamed or infected. They can also develop cancer. Testicular cancer is rare and highly treatable. It usually happens between the ages of 15 and 40.
It sits within Endocrine System, Men, Sexual Health Issues and Male Reproductive System.
The lead U.S. institute for this subject is the National Institute of Diabetes and Digestive and Kidney Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Testicular Disorders
504 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer SurvivorsUniversity of Southern California
- Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary TumorsNational Cancer Institute (NCI)
- Comparison of Posterior QLB and QIPB in Pediatric Undescended Testis Surgery.Medipol University
- Late Subclinical Cardiovascular Disease in Testicular Cancer SurvivorsIndiana University
- A Single-arm, Phase II Clinical Trial of ASPIRin to prEvent Venous Thromboembolism in Patients With Advanced Germ Cell Tumors Receiving ChemotherapyWake Forest University Health Sciences
- DESTINY-PANTUMOUR04AstraZeneca
Research already completed
- Cause of Familial Testicular CancerNational Cancer Institute (NCI)
- Study of Gemcitabine, Oxaliplatin, and Paclitaxel in Patients With Refractory Germ Cell CarcinomaUniversity of Southern California
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Diagnosis and Tests
- DHEA Sulfate TestNational Library of Medicine
- Genital Problems in MenAmerican Academy of Family Physicians
- Testicular biopsyMedical Encyclopedia
- Testosterone Levels TestNational Library of Medicine
- Ultrasound -- ScrotumRadiological Society of North America
Treatments and Therapies
- Testicular torsion repair - seriesMedical Encyclopedia
- Varicocele EmbolizationRadiological Society of North America
Prevention and Risk Factors
- Testicular Self-ExamMayo Foundation for Medical Education and Research
Clinical Trials
- ClinicalTrials.gov: CryptorchidismNational Institutes of Health
- ClinicalTrials.gov: Genital Diseases, MaleNational Institutes of Health
- ClinicalTrials.gov: Testicular DiseasesNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Testicular Diseases. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Testicular Disorders, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.