Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Small Intestine Disorders
Your small intestine is the longest part of your digestive system - about twenty feet long! It connects your stomach to your large intestine (or colon) and folds many times to fit inside your abdomen. Your small intestine does most of the digesting of the foods you eat. It has three areas called the duodenum, the ileum, and the jejunum.
Problems with the small intestine can include:
- Bleeding
- Celiac disease
- Crohn's disease
- Infections
- Intestinal cancer
- Intestinal obstruction
- Irritable bowel syndrome
- Ulcers, such as peptic ulcer
Treatment of disorders of the small intestine depends on the cause.
It sits within Digestive System.
The lead U.S. institute for this subject is the National Institute of Diabetes and Digestive and Kidney Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Small Intestine Disorders
1,148 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid TumorsAmgen
- A Study of BMS-986488 as Monotherapy and Combination Therapy in Participants With Advanced Malignant TumorsBristol-Myers Squibb
- A Study of IDP-001 in Advanced or Metastatic Solid TumorsInduPro, Inc.
- Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal CancersNovartis Pharmaceuticals
- Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid TumorsAstraZeneca
- Phase I Study of JFI447 [68Ga]Ga-DFC413 and Comparison to FFG233 [68Ga]Ga-NNS309 in Patients With Solid TumorsNovartis Pharmaceuticals
Research already completed
- A Phase I Trial of LY3143921 Hydrate in Solid TumoursCancer Research UK
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Your Digestive System and How It WorksNational Institute of Diabetes and Digestive and Kidney Diseases
Diagnosis and Tests
- Bacteria Culture TestNational Library of Medicine
- Capsule EndoscopyMayo Foundation for Medical Education and Research
- Fecal Occult Blood Test (FOBT)National Library of Medicine
- Ova and Parasite TestNational Library of Medicine
- Small Bowel BleedingAmerican College of Gastroenterology
- Small Bowel Follow-ThroughRadiological Society of North America
- Upper GI SeriesNational Institute of Diabetes and Digestive and Kidney Diseases
Treatments and Therapies
- IntestineHealth Resources and Services Administration
- Meckel's diverticulectomy - seriesMedical Encyclopedia
- Small bowel resection - seriesMedical Encyclopedia
Related Issues
- Ostomy Surgery of the BowelNational Institute of Diabetes and Digestive and Kidney Diseases
Clinical Trials
- ClinicalTrials.gov: Duodenal DiseasesNational Institutes of Health
- ClinicalTrials.gov: Ileal DiseasesNational Institutes of Health
- ClinicalTrials.gov: Intestinal DiseasesNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Jejunal Diseases, Duodenal Diseases, Ileal Diseases. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Small Intestine Disorders, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.