Also called: IBS · Irritable colon
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a problem that affects the large intestine. It can cause abdominal cramping, bloating, and a change in bowel habits. Some people with the disorder have constipation. Some have diarrhea. Others go back and forth between the two. Although IBS can cause a great deal of discomfort, it does not harm the intestines.
IBS is common. It affects about twice as many women as men and is most often found in people younger than 45 years. No one knows the exact cause of IBS. There is no specific test for it. Your doctor may run tests to be sure you don't have other diseases. These tests may include stool sampling tests, blood tests, and x-rays. Your doctor may also do a test called a sigmoidoscopy or colonoscopy. Most people diagnosed with IBS can control their symptoms with diet, stress management, probiotics, and medicine.
It sits within Digestive System.
The lead U.S. institute for this subject is the National Institute of Diabetes and Digestive and Kidney Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Irritable Bowel Syndrome
1,163 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- A Study of Virtual Reality and Linaclotide for IBS-CMayo Clinic
- Single-center Exploratory Study of the Intestinal Microbiota in Patients Treated for Irritable Bowel Syndrome With Predominant Constipation and Methane ProductionHospices Civils de Lyon
- Enzymax DuoBiotics for Irritable Bowel SyndromeGala Servicios Clinicos S.L.
- Huanghou Zhixie Diwan in the Treatment of Irritable Bowel Syndrome With Diarrhea (IBS-D)Lei Yunshang Group
- Efficacy and Mechanistic Evaluation of Hewei Anchang Formula for Overlapping Gastrointestinal Symptoms in Patients With Coexisting Functional Dyspepsia and Diarrhea-Predominant Irritable Bowel SyndromeXiyuan Hospital of China Academy of Chinese Medical Sciences
- A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)Eli Lilly and Company
Research already completed
- Low-FODMAP vs Lactose-Gluten-Free Diet in Patients With Irritable Bowel SyndromeAntalya Bilim University
- Study Evaluating the Efficacy of Different Mixes of HMO-2FL + Humiome® Post LB on IBS Gastrointestinal Symptomsdsm-firmenich Switzerland AG
- GI Permeability Change in Response to Aquamin®James Varani
- Efficacy of PosBion® Postbiotic Supplementation in Adults With Irritable Bowel SyndromeMy Myracle Sdn.Bhd
- Changyanning Tablet for the Treatment of Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)Mei Han
- Effects of Relaxation Response Mind-body Intervention in Patients With IBS and IBDMassachusetts General Hospital
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Definition and Facts for Irritable Bowel SyndromeNational Institute of Diabetes and Digestive and Kidney Diseases
- Irritable Bowel SyndromeMayo Foundation for Medical Education and Research
- Irritable Bowel SyndromeAcademy of Nutrition and Dietetics
Symptoms
- Recognizing SymptomsInternational Foundation for Gastrointestinal Disorders
- Symptoms and Causes of Irritable Bowel SyndromeNational Institute of Diabetes and Digestive and Kidney Diseases
Diagnosis and Tests
- Calprotectin Stool TestNational Library of Medicine
- Colonoscopy: MedlinePlus Health TopicNational Library of Medicine
- Diagnosis of Irritable Bowel SyndromeNational Institute of Diabetes and Digestive and Kidney Diseases
Treatments and Therapies
- 7 Tips: Irritable Bowel Syndrome and Complementary Health ApproachesNational Center for Complementary and Integrative Health
- Hypnosis for IBSInternational Foundation for Gastrointestinal Disorders
- Irritable Bowel Syndrome: What You Need To KnowNational Center for Complementary and Integrative Health
- Medications for IBSInternational Foundation for Gastrointestinal Disorders
- Peppermint OilNational Center for Complementary and Integrative Health
- Probiotics: Usefulness and SafetyNational Center for Complementary and Integrative Health
- Psychological TreatmentsInternational Foundation for Gastrointestinal Disorders
Living With
- Diet - An Important 1st Step in IBS TreatmentInternational Foundation for Gastrointestinal Disorders
- Eating, Diet, and Nutrition for Irritable Bowel SyndromeNational Institute of Diabetes and Digestive and Kidney Diseases
- Relaxation Techniques to Manage IBS SymptomsInternational Foundation for Gastrointestinal Disorders
- Sleep and IBS -- 40% of Patients Report IssuesInternational Foundation for Gastrointestinal Disorders
Related Issues
- Gut Troubles: Pain, Gassiness, Bloating, and MoreNational Institutes of Health
- IBS and Non-GI Functional DisordersInternational Foundation for Gastrointestinal Disorders
- Spastic Colon: What Does It Mean?Mayo Foundation for Medical Education and Research
Statistics and Research
- Irritable Bowel Syndrome and Complementary Health Approaches: What the Science SaysNational Center for Complementary and Integrative Health
Clinical Trials
- ClinicalTrials.gov: Colonic Diseases, FunctionalNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Colonic Diseases, Functional. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Irritable Bowel Syndrome, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.