Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Leg Injuries and Disorders
Your legs are made up of bones, blood vessels, muscles, and other connective tissue. They are important for motion and standing. Playing sports, running, falling, or having an accident can damage your legs. Common leg injuries include sprains and strains, joint dislocations, and fractures (broken bones).
These injuries can affect the entire leg, or just the foot, ankle, knee, or hip. Certain diseases also lead to leg problems. For example, knee osteoarthritis, common in older people, can cause pain and limited motion. Problems in your veins in your legs can lead to varicose veins or deep vein thrombosis.
It sits within Bones, Joints and Muscles and Injuries and Wounds.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Leg Injuries and Disorders
1,454 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- ZEPU-AI1 Gait Robot Training Study (ZEPUAI1RCT)Bangladesh Medical University
- ZEPU-AI5 Strength Training Study (ZEPUAI5RCT)Bangladesh Medical University
- Effect of Photobiomodulation on Healing of Venous Leg UlcersUniversity of Nove de Julho
- Randomized Controlled Trial for Treatment of Pain and Assessment of Wound Healing in Chronic Venous Leg Ulcers Using Near Infrared Laser TherapyWake Forest University Health Sciences
- Psychological Readiness and Return to Sport After ACL ReconstructionBiruni University
- Evaluating the Efficacy of a Mobile Application in Postoperative RehabilitationYale University
Research already completed
- Vacuum Compression Therapy for Chronic Lower Limb UlcersBTL Industries Ltd.
- Investigation of the Effects of Different Exercise on Wound Healing in Patients wıth Diabetic Foot WoundsHarran University
- Can we 'Hear' Femoral Neck Fractures? Ultrasound Guided Diagnosis of Femoral Neck FracturesFrisius Medisch Centrum
- Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU)Rion Inc.
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Diagnosis and Tests
- Ankle-Brachial IndexMayo Foundation for Medical Education and Research
- Femur X-Ray Exam (For Parents)Nemours Foundation
- How Does a Leg Length X-Ray Work? (For Parents)Nemours Foundation
- Leg ProblemsAmerican Academy of Family Physicians
- X-Ray Exam: Lower Leg (Tibia and Fibula) (For Parents)Nemours Foundation
Living With
- Mobility Aids: MedlinePlus Health TopicNational Library of Medicine
Related Issues
- Sports InjuriesNational Institute of Arthritis and Musculoskeletal and Skin Diseases
Clinical Trials
- ClinicalTrials.gov: Intermittent ClaudicationNational Institutes of Health
- ClinicalTrials.gov: Leg InjuriesNational Institutes of Health
- ClinicalTrials.gov: Leg Length InequalityNational Institutes of Health
- ClinicalTrials.gov: Leg UlcerNational Institutes of Health
- ClinicalTrials.gov: Muscle CrampNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Leg Injuries, Femoral Fractures, Leg Length Inequality, Tibial Fractures, Leg Ulcer. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Leg Injuries and Disorders, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.