Also called: DVT
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Deep Vein Thrombosis
Deep vein thrombosis, or DVT, is a blood clot that forms in a vein deep in the body. Most deep vein clots occur in the lower leg or thigh. If the vein swells, the condition is called thrombophlebitis. A deep vein thrombosis can break loose and cause a serious problem in the lung, called a pulmonary embolism.
Sitting still for a long time can make you more likely to get a DVT. Some medicines and disorders that increase your risk for blood clots can also lead to DVTs. Common symptoms are :
- Warmth and tenderness over the vein
- Pain or swelling in the part of the body affected
- Skin redness
Treatment includes medicines to ease pain and inflammation, break up clots and keep new clots from forming. Keeping the affected area raised and applying moist heat can also help. If you are taking a long car or plane trip, take a break, walk or stretch your legs and drink plenty of liquids.
It sits within Blood, Heart and Circulation.
The lead U.S. institute for this subject is the National Heart, Lung, and Blood Institute.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Deep Vein Thrombosis
698 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- ClotTriever® Thrombectomy System Use-Result Survey in JapanInari Medical
- The PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue MorbidityUniversity of Calgary
- DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein ThrombosisInari Medical
- Colchicine to Quench the Inflammatory Response After Deep Vein Thrombosis (The Conquer-DVT Pilot Trial)Ottawa Hospital Research Institute
- REGN7508 in Adult Participants for Prevention of Cancer-Associated ThrombosisRegeneron Pharmaceuticals
- REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult ParticipantsRegeneron Pharmaceuticals
Research already completed
- Effect of Emergency Department Bedside Compression Ultrasonography on Door-to-Disposition Time in Patients Suspicious for Lower Extremity Deep Venous ThrombosisHenry Ford Health System
- A Study to Learn More About How Well BAY3018250 Works and How Safe it is for People With Proximal Deep Vein ThrombosisBayer
- Personalized Medicine Decision-Making in a Virtual Clinical SettingNational Human Genome Research Institute (NHGRI)
- Determining the Validity of ThinkSono Guidance for Ultrasound Image Acquisition and Remote DetectionThinkSono, Ltd.
- Apixaban vs Rivaroxaban vs No Anticoagulant to Prevent EHIT After Great Saphenous Vein Laser AblationHeart, Artery, and Vein Center of Fresno
- Emulation of the RECORD3 Trial Using Healthcare Claims DataBrigham and Women's Hospital
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- About Venous Thromboembolism (Blood Clots)Centers for Disease Control and Prevention
- Deep Vein ThrombosisAmerican Academy of Orthopaedic Surgeons
- What Is Venous Thromboembolism?National Heart, Lung, and Blood Institute
Diagnosis and Tests
- D-Dimer TestNational Library of Medicine
- Doppler UltrasoundNational Library of Medicine
- Venography -- Blood Flow Examination of VeinsRadiological Society of North America
- Venous UltrasoundRadiological Society of North America
Treatments and Therapies
- Blood Thinners: MedlinePlus Health TopicNational Library of Medicine
- Catheter-Directed ThrombolysisRadiological Society of North America
- IVC (Inferior Vena Cava) FiltersRadiological Society of North America
Prevention and Risk Factors
- How to Spot and Prevent Deep Vein ThrombosisNational Institutes of Health
- Preventing Deep Vein ThrombosisAmerican College of Obstetricians and Gynecologists
Related Issues
- Chronic Venous InsufficiencyJohns Hopkins Medicine
- Post-Thrombotic SyndromeNational Blood Clot Alliance
- Postthrombotic SyndromeAmerican Heart Association
- Travelers' Health: Deep Vein Thrombosis and Pulmonary EmbolismCenters for Disease Control and Prevention
- Understanding Your Risk for Blood Clots with TravelCenters for Disease Control and Prevention
- Venous Thromboembolism and Marathon AthletesAmerican Heart Association
Statistics and Research
- Data and Statistics on Venous ThromboembolismCenters for Disease Control and Prevention
Clinical Trials
- ClinicalTrials.gov: PhlebitisNational Institutes of Health
- ClinicalTrials.gov: ThrombophlebitisNational Institutes of Health
- ClinicalTrials.gov: Venous ThrombosisNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Venous Thrombosis. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Deep Vein Thrombosis, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.