Also called: Eosinophilia
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Eosinophilic Disorders
Eosinophils are a type of white blood cell. They help fight off infections and play a role in your body's immune response. They can also build up and cause inflammation.
Normally your blood doesn't have a large number of eosinophils. Your body may produce more of them in response to:
- Allergic disorders
- Skin conditions
- Parasitic and fungal infections
- Autoimmune diseases
- Some cancers
- Bone marrow disorders
In some conditions, the eosinophils can move outside the bloodstream and build up in organs and tissues. This can happen in many different parts of the body, including the esophagus, heart, lungs, blood, and intestines. Treatment of eosinophilic disorders can vary, depending on the cause and which part of the body is affected. Steroids are often part of the treatment.
It sits within Digestive System, Blood, Heart and Circulation, Lungs and Breathing and Immune System.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Eosinophilic Disorders
733 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease ProgressionNational Institute of Allergy and Infectious Diseases (NIAID)
- The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United StatesNational Institute of Allergy and Infectious Diseases (NIAID)
- Efficacy and Safety of Tezepelumab in Patients With Eosinophilic EsophagitisAstraZeneca
- Prevalence and Clinical Outcome of Eosinophilic COPDAssiut University
- Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety TrialGlaxoSmithKline
- The DiNAM-EoE-C Study: Esophageal Distensibility and Novel Assessment of Motility in Eosinophilic EsophagitisFondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Research already completed
- Screening Protocol for Genetic Diseases of Allergic InflammationNational Institute of Allergy and Infectious Diseases (NIAID)
- Efficacy and Safety of Mepolizumab in Adults With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)/ Eosinophilic Chronic Rhinosinusitis (ECRS)GlaxoSmithKline
- Eltrombopag Olamine in Improving Platelet Recovery in Older Patients With Acute Myeloid Leukemia Undergoing ChemotherapyCase Comprehensive Cancer Center
- Natural History of Severe Allergic Inflammation and ReactionsNational Institute of Allergy and Infectious Diseases (NIAID)
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- EosinophiliaMayo Foundation for Medical Education and Research
- Eosinophilic DisordersMerck & Co., Inc.
Diagnosis and Tests
- Upper GI EndoscopyNational Institute of Diabetes and Digestive and Kidney Diseases
Living With
- Feeding TubesAmerican Partnership for Eosinophilic Disorders
Genetics
- Eosinophil peroxidase deficiency: MedlinePlus GeneticsNational Library of Medicine
- PDGFRA-associated chronic eosinophilic leukemia: MedlinePlus GeneticsNational Library of Medicine
- PDGFRB-associated chronic eosinophilic leukemia: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: Churg-Strauss SyndromeNational Institutes of Health
- ClinicalTrials.gov: EosinophiliaNational Institutes of Health
- ClinicalTrials.gov: Hypereosinophilic SyndromeNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Eosinophilia. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Eosinophilic Disorders, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.