Also called: Escherichia coli
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About E. coli Infections
E. coli is the name of a type of bacteria that lives in your intestines. Most types of E. coli are harmless. However, some types can make you sick and cause diarrhea. One type causes travelers' diarrhea. The worst type of E. coli causes bloody diarrhea, and can sometimes cause kidney failure and even death. These problems are most likely to occur in children and in adults with weak immune systems.
You can get E. coli infections by eating foods containing the bacteria. Symptoms of infection include:
- Nausea or vomiting
- Severe abdominal cramps
- Watery or very bloody diarrhea
- Fatigue
- Fever
To help avoid food poisoning and prevent infection, handle food safely. Cook meat well, wash fruits and vegetables before eating or cooking them, and avoid unpasteurized milk and juices. You can also get the infection by swallowing water in a swimming pool contaminated with human waste.
Most cases of E. coli infection get better without treatment in 5 to 10 days.
It sits within Infections.
The lead U.S. institute for this subject is the National Institute of Allergy and Infectious Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on E. coli Infections
170 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Genomic and Phenotypic Diversity of Carbapenemase-producing Escherichia Coli Strains Circulating in Southern FranceCentre Hospitalier Universitaire de Nīmes
- Hyperhydration in Children With Shiga Toxin-Producing E. Coli InfectionUniversity of Calgary
- Bacteriophage Therapy in Spinal Cord Injury Patients With BacteriuriaBarbara Trautner
- A Study on the Safety and Immune Response of a Urinary Tract Infection (UTI) Vaccine in Adults 18-64 Years of Age and Clinical Efficacy in Females 18-64 Years of AgeGlaxoSmithKline
- Antibiofilm Activity of Chitosan Nanoparticles Against Uropathogenic Escherichia ColiAssiut University
- A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial)Locus Biosciences
Research already completed
- Perinatal Transmission of MDR BacteriaAnn & Robert H Lurie Children's Hospital of Chicago
- Developing Microbials to Fight Extended-spectrum Beta-lactamase (ESBL)-Producing Escherichia ColiUniversity Hospital, Basel, Switzerland
- Safety, Tolerability, Pharmacokinetic and Microbiological Investigation of GSK3882347 in Female Participants With Urinary Tract InfectionsGlaxoSmithKline
- Shigella CVD 31000: Study of Responses With Shigella-ETEC Vaccine Strain CVD 1208S-122University of Maryland, Baltimore
- ShigETEC Vaccine Study in BangladeshEveliqure Biotechnologies GmbH
- Meatsafe Food Storage and Diarrhea Prevention Trial in Urban BangladeshUniversity of California, Berkeley
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- About Escherichia coli InfectionCenters for Disease Control and Prevention
- E. coliDepartment of Health and Human Services
Prevention and Risk Factors
- How to Prevent E. coli InfectionCenters for Disease Control and Prevention
Related Issues
- Farm AnimalsCenters for Disease Control and Prevention
- Ground Beef and Food SafetyDepartment of Agriculture, Food Safety and Inspection Service
Clinical Trials
- ClinicalTrials.gov: Escherichia coli InfectionsNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Escherichia coli Infections. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for E. coli Infections, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.