Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About COPD
COPD (chronic obstructive pulmonary disease) is a group of lung diseases that make it hard to breathe and get worse over time.
Normally, the airways and air sacs in your lungs are elastic or stretchy. When you breathe in, the airways bring air to the air sacs. The air sacs fill up with air, like a small balloon. When you breathe out, the air sacs deflate, and the air goes out. If you have COPD, less air flows in and out of your airways because of one or more problems:
- The airways and air sacs in your lungs become less elastic
- The walls between many of the air sacs are destroyed
- The walls of the airways become thick and inflamed
- The airways make more mucus than usual and can become clogged
COPD includes two main types:
- Emphysema affects the air sacs in your lungs, as well as the walls between them. They become damaged and are less elastic.
- Chronic bronchitis, in which the lining of your airways is constantly irritated and inflamed. This causes the lining to swell and make mucus.
Most people with COPD have both emphysema and chronic bronchitis, but how severe each type is can be different from person to person.
The cause of COPD is usually long-term exposure to irritants that damage your lungs and airways. In the United States, cigarette smoke is the main cause. Pipe, cigar, and other types of tobacco smoke can also cause COPD, especially if you inhale them.
Exposure to other inhaled irritants can contribute to COPD. These include secondhand smoke, air pollution, and chemical fumes or dusts from the environment or workplace.
Rarely, a genetic condition called alpha-1 antitrypsin deficiency can play a role in causing COPD.
The risk factors for COPD include:
- Smoking. This is the main risk factor. Up to 75% of people who have COPD smoke or used to smoke.
- Long-term exposure to other lung irritants, such as secondhand smoke, air pollution, and chemical fumes and dusts from the environment or workplace
- Age. Most people who have COPD are at least 40 years old when their symptoms begin.
- Genetics. This includes alpha-1 antitrypsin deficiency, which is a genetic condition. Also, smokers who get COPD are more likely to get it if they have a family history of COPD.
- Asthma. People who have asthma have more risk of developing COPD than people who don't have asthma. But most people with asthma will not get COPD.
At first, you may have no symptoms or only mild symptoms. As the disease gets worse, your symptoms usually become more severe. They can include:
- Frequent coughing or a cough that produces a lot of mucus
- Wheezing
- A whistling or squeaky sound when you breathe
- Shortness of breath, especially with physical activity
- Tightness in your chest
Some people with COPD get frequent respiratory infections such as colds and the flu. In severe cases, COPD can cause weight loss, weakness in your lower muscles, and swelling in your ankles, feet, or legs.
Your health care provider may use many tools to make a diagnosis:
- A medical history, which includes asking about your symptoms
- A family history
- Various tests, such as lung function tests, a chest x-ray or CT scan, and blood tests
Your doctor will diagnose COPD based on your signs and symptoms, your medical and family histories, and test results.
There is no cure for COPD. However, treatments can help with symptoms, slow the progress of the disease, and improve your ability to stay active. There are also treatments to prevent or treat complications of the disease. Treatments include:
- Lifestyle changes, such as Quitting smoking if you are a smoker. This is the most important step you can take to treat COPD.
- Avoiding secondhand smoke and places where you might breathe in other lung irritants
- Ask your health care provider for an eating plan that will meet your nutritional needs. Also ask about how much physical activity you can do. Physical activity can strengthen the muscles that help you breathe and improve your overall wellness.
- Bronchodilators, which relax the muscles around your airways. This helps open your airways and makes breathing easier. Most bronchodilators are taken through an inhaler. In more severe cases, the inhaler may also contain steroids to reduce inflammation.
- Vaccines for the flu and pneumococcal pneumonia, since people with COPD are at higher risk for serious problems from these diseases
- Antibiotics if you get a bacterial lung infection
- An exercise program
- Disease management training
- Nutritional counseling
- Psychological counseling
- For COPD that is mainly related to emphysema, there are surgeries that: Remove damaged lung tissue
- Remove large air spaces (bullae) that can form when air sacs are destroyed. The bullae can interfere with breathing.
If you have COPD, it's important to know when and where to get help for your symptoms. You should get emergency care if you have severe symptoms, such as trouble catching your breath or talking. Call your health care provider if your symptoms are getting worse or if you have signs of an infection, such as a fever.
Since smoking causes most cases of COPD, the best way to prevent it is to not smoke. It's also important to try to avoid lung irritants such as secondhand smoke, air pollution, chemical fumes, and dusts.
It sits within Older Adults and Lungs and Breathing.
The lead U.S. institute for this subject is the National Heart, Lung, and Blood Institute.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on COPD
5,493 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Primary Palliative Care - a Feasibility Cluster TrialUniversity of Coimbra
- Prevalence and Clinical Outcome of Eosinophilic COPDAssiut University
- Unilateral vs. Bilateral Lung Volume Reduction SurgeryRigshospitalet, Denmark
- eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 InflammationGlaxoSmithKline
- PRA-216 COPD Safety and Biomarker StudyPrana Therapies Inc
- A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary DiseasePfizer
Research already completed
- A Pharmacist-Led Intervention to Increase Inhaler Access and Reduce Hospital Readmissions (PILLAR)Vanderbilt University Medical Center
- Examining the Effectiveness of Single-Limb Exercise Training for COPD Patients During Exacerbation PeriodsAlper Kemal Gürbüz
- Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of ExacerbationsAstraZeneca
- The Effects of Oscillatory Positive Expiratory Pressure (OPEP) Therapy in Patients With COPDMcGill University Health Centre/Research Institute of the McGill University Health Centre
- Home-based Body Weight Exercise With Blood Flow Restriction (BFR): Feasibility of a Novel Rehabilitation Intervention in COPD Patients (HomeBFR-COPD)Mrs Hanoof Aljohani
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Chronic Obstructive Pulmonary Disease (COPD)American Thoracic Society
- Chronic Obstructive Pulmonary Disease (COPD)Centers for Disease Control and Prevention
- Learn More, Breathe Better: Are You at Risk for COPD?National Heart, Lung, and Blood Institute
Diagnosis and Tests
- Alpha-1 Antitrypsin TestingNational Library of Medicine
- Arterial Blood Gas (ABG) TestNational Library of Medicine
- Breathlessness -- Shortness of BreathAmerican Thoracic Society
- Bronchoscopy and Bronchoalveolar Lavage (BAL)National Library of Medicine
- Lung Function TestsNational Library of Medicine
Treatments and Therapies
- Medicines for COPDAmerican Thoracic Society
Prevention and Risk Factors
- Lower Your COPD Risk at Any AgeNational Heart, Lung, and Blood Institute
Living With
- Breathe Better With COPD: Living With Chronic Obstructive Pulmonary DiseaseNational Institutes of Health
- Breathing and RelaxationNational Jewish Health
- COPD Caregiver's ToolkitNational Heart, Lung, and Blood Institute
- How to Cough up Mucus and Phlegm from Chest CongestionNational Jewish Health
- Nutrition and COPDAmerican Lung Association
- Oxygen TherapyAmerican Lung Association
- Pulmonary Rehabilitation: MedlinePlus Health TopicNational Library of Medicine
Related Issues
- Asthma and COPD: Differences and SimilaritiesAmerican Academy of Allergy, Asthma, and Immunology
- Five Steps for Successful Flying with OxygenAmerican Lung Association
- Marvels of Mucus and Phlegm: The Slime That Keeps You HealthyNational Institutes of Health
- Oxygen Therapy: Traveling with OxygenAmerican Lung Association
Statistics and Research
- FastStats: Chronic Obstructive Pulmonary Disease (COPD) Includes: Chronic Bronchitis and EmphysemaNational Center for Health Statistics
Clinical Trials
- ClinicalTrials.gov: Lung Diseases, ObstructiveNational Institutes of Health
- ClinicalTrials.gov: Pulmonary Disease, Chronic ObstructiveNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Pulmonary Disease, Chronic Obstructive. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for COPD, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.