Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Oxygen Therapy
Oxygen is a gas that your body needs to work properly. Your cells need oxygen to make energy. Your lungs absorb oxygen from the air you breathe. The oxygen enters your blood from your lungs and travels to your organs and body tissues.
Certain medical conditions can cause your blood oxygen levels to be too low. Low blood oxygen may make you feel short of breath, tired, and confused. It can also damage your body. Oxygen therapy can help you get more oxygen.
Oxygen therapy is a treatment that provides you with extra oxygen to breathe in. It is also called supplemental oxygen. It is only available through a prescription from your health care provider. You may get it in the hospital, another medical setting, or at home. Some people only need it for a short period of time. Others will need long-term oxygen therapy.
There are different types of devices that can give you oxygen. Some use tanks of liquid or gas oxygen. Others use an oxygen concentrator, which pulls oxygen out of the air. You will get the oxygen through a nose tube (cannula), a mask, or a tent. The extra oxygen is breathed in along with normal air.
There are portable versions of the tanks and oxygen concentrators. They can make it easier for you to move around while using your therapy.
You may need oxygen therapy if you have a condition that causes low blood oxygen, such as:
- COPD (chronic obstructive pulmonary disease)
- Pneumonia
- COVID-19
- A severe asthma attack
- Late-stage heart failure
- Cystic fibrosis
- Sleep apnea
Oxygen therapy is generally safe, but it can cause side effects. They include a dry or bloody nose, tiredness, and morning headaches.
Oxygen poses a fire risk, so you should never smoke or use flammable materials when using oxygen. If you use oxygen tanks, make sure your tank is secured and stays upright. If it falls and cracks or the top breaks off, the tank can fly like a missile.
Hyperbaric oxygen therapy (HBOT) is a different type of oxygen therapy. It involves breathing oxygen in a pressurized chamber or tube. That allows your lungs to gather up to three times more oxygen than you would get by breathing oxygen at normal air pressure. The extra oxygen moves through your blood and to your organs and body tissues.
HBOT is used to treat certain serious wounds, burns, injuries, and infections. It also treats air or gas embolisms (bubbles of air in your bloodstream), decompression sickness suffered by divers, and carbon monoxide poisoning.
But some treatment centers claim that HBOT can treat almost anything, including Alzheimer's disease, autism, cancer, and Lyme disease. The U.S. Food and Drug Administration (FDA) has not cleared or approved the use of HBOT for these conditions. There are risks to using HBOT, so always check with your provider before you try it.
It sits within Lungs and Breathing and Surgery and Rehabilitation.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Oxygen Therapy
2,934 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Study on the Effect of Hyperbaric Oxygen Intervention on Relieving Sports Fatigue of SailorsShanghai Research Institute of Sports Science
- Caffeine Optimization for Oxygen Saturation Index in ELBW InfantsUniversity of Rochester
- Long-Term Outcomes Following HBOTSummit Hyperbarics and Wellness
- High-flow Nasal Cannula Versus Conventional Oxygen During Awake Tracheal Intubation With Difficult AirwaysWenxian Li
- Supplementing Neuro-Energy to Aid CognitionUniversity of Pennsylvania
- Effect of High-Flow Humidified Oxygen on Ventilatory Work During the Spontaneous Breathing TrialUniversity Hospital, Grenoble
Research already completed
- Ventilation Mode and Atelectasis After Prone-Position Surgery: A Lung Ultrasound StudyProf. Dr. Cemil Tascıoglu Education and Research Hospital Organization
- Hyperbaric Oxygen Therapy in Sickle Cell PainUniversity of Nebraska
- Oxygen Delivery Methods of Nasal Catheter on the Incidence of Hypoxemia in Patients With Painless GastroscopyNanjing First Hospital, Nanjing Medical University
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Lung Disease TreatmentsNational Heart, Lung, and Blood Institute
- Oxygen TherapyAmerican Thoracic Society
- Oxygen TherapyAmerican Lung Association
Related Issues
- Five Steps for Successful Flying with OxygenAmerican Lung Association
- Mechanical VentilationAmerican Thoracic Society
- On the Go with a Portable Oxygen Concentrator (POC)National Jewish Health
- Oxygen Therapy: Traveling with OxygenAmerican Lung Association
- Oxygen Therapy: Using Oxygen SafelyAmerican Lung Association
Clinical Trials
- ClinicalTrials.gov: Hyperbaric OxygenationNational Institutes of Health
- ClinicalTrials.gov: Oxygen Inhalation TherapyNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Oxygen Inhalation Therapy. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Oxygen Therapy, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.