Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Cancer in Children
Cancer is a group of related diseases. In all types of cancer, some of the body's cells begin to divide without stopping and spread into surrounding tissues.
Normally, new cells form as you need them, replacing old cells that die. Sometimes, this process goes wrong. New cells form when you don't need them, and old cells don't die when they should. The extra cells can form a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer. Malignant tumors are cancer, and the cancer cells can spread to nearby tissues. They can also break away and spread to other parts of the body.
Children can get cancer in the same parts of the body as adults, but there are differences. Childhood cancers may happen suddenly, without early symptoms. Some types can often be cured. The most common children's cancer is leukemia. Some of the other more common types of cancer in children include brain tumors, lymphoma, and soft tissue sarcoma.
Symptoms and treatment depend on the type of cancer and how advanced it is. Treatments may include:
- Surgery
- Radiation therapy
- Chemotherapy
- Stem cell transplants
- Targeted therapy, which uses drugs or other substances that attack specific cancer cells with less harm to normal cells
It sits within Cancers and Children and Teenagers.
The lead U.S. institute for this subject is the National Cancer Institute.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Cancer in Children
2,341 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic LeukemiaChildren's Oncology Group
- Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable OsteosarcomaH. Lee Moffitt Cancer Center and Research Institute
- NCI Childhood Cancer Data Initiative (CCDI) Led Pediatric, Adolescent, and Young Adult Rare Cancer Registry for Very Rare Solid TumorsNational Cancer Institute (NCI)
- Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care RadiationM.D. Anderson Cancer Center
- A Study to Assess a Medicine Called Tovorafenib in Japanese Children and Young Adults With Brain TumoursIpsen
- Natural History Study of Early Life Exposures in Agriculture (ELEA)National Cancer Institute (NCI)
Research already completed
- NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid TumorsNational Cancer Institute (NCI)
- 05-001: Treatment of Acute Lymphoblastic Leukemia in ChildrenDana-Farber Cancer Institute
- Prospective Trial of Vaccine Responses in Childhood Cancer SurvivorsMemorial Sloan Kettering Cancer Center
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Cancer in Children and AdolescentsNational Cancer Institute
- Childhood CancerAmerican Cancer Society
- Childhood CancerNemours Foundation
- Children with Cancer: A Guide for ParentsNational Cancer Institute
Diagnosis and Tests
- Finding and Diagnosing Cancer in ChildrenAmerican Cancer Society
Treatments and Therapies
- Childhood Carcinoma of Unknown Primary TreatmentNational Cancer Institute
- Childhood Thyroid Cancer TreatmentNational Cancer Institute
- Drugs Approved for Childhood CancersNational Cancer Institute
- Drugs Approved for RhabdomyosarcomaNational Cancer Institute
- Immunotherapy to Treat Cancer (For Parents)Nemours Foundation
- Rare Cancers of Childhood TreatmentNational Cancer Institute
- Side Effects of Chemotherapy and Radiation (For Parents)Nemours Foundation
Living With
- Bone Health After Cancer TreatmentNemours Foundation
- Care for Childhood Cancer SurvivorsNational Cancer Institute
- Coping with Cosmetic Effects of Cancer TreatmentNemours Foundation
- Going to School during and after Cancer TreatmentAmerican Cancer Society
Related Issues
- Effects of Cancer Treatment on Fertility (For Parents)Nemours Foundation
- Late Effects of Treatment for Childhood CancerNational Cancer Institute
Genetics
- Mosaic variegated aneuploidy syndrome: MedlinePlus GeneticsNational Library of Medicine
Statistics and Research
- Advances in Childhood Cancer: Making Personalized Treatments a RealityNational Institutes of Health
- Childhood Cancer StatisticsCureSearch for Children's Cancer
- Childhood Cancer Survivor Study: An OverviewNational Cancer Institute
Clinical Trials
- Children's Assent to Clinical Trial ParticipationNational Cancer Institute
- ClinicalTrials.gov: Cancer in ChildrenNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Neoplasms. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Cancer in Children, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.