Also called: Alcohol abuse · Alcohol dependence · Alcoholism
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Alcohol Use Disorder (AUD)
For most adults, moderate alcohol use is probably not harmful. Your risk of developing an alcohol use disorder (AUD) depends on how much, how often, and how quickly you drink alcohol. Alcohol misuse means that drinking causes distress and harm. Over time alcohol misuse can increase your risk of AUD.
AUD can range from mild to severe, depending on the symptoms. Severe AUD is sometimes called alcoholism or alcohol dependence.
AUD is a disease that causes:
- Craving - a strong need to drink
- Loss of control - not being able to stop drinking once you've started
- Negative emotional state - feeling anxious and irritable when you are not drinking
Binge drinking is a type of alcohol misuse. It means drinking so much at once that your blood alcohol concentration (BAC) level is 0.08% or more. For a man, this usually happens after having 5 or more drinks within a few hours. For a woman, it is after about 4 or more drinks within a few hours. Not everyone who binge drinks has an AUD, but they are at higher risk for getting one.
Too much alcohol is dangerous. Heavy drinking can increase the risk of certain cancers. It may lead to liver diseases, such as alcohol-associated liver disease (ALD) and cirrhosis. It can also cause damage to the brain and other organs. Drinking during pregnancy can harm your fetus. Alcohol also increases the risk of death from car crashes, injuries, homicide, and suicide.
You may have an AUD if you can answer yes to two or more of these questions:
In the past year, have you:
- Ended up drinking more or for a longer time than you had planned to?
- Wanted to cut down or stop drinking, or tried to, but couldn't?
- Spent a lot of your time drinking or recovering from drinking?
- Felt a strong need to drink?
- Found that drinking - or being sick from drinking - often interfered with your family life, job, or school?
- Kept drinking even though it was causing trouble with your family or friends?
- Given up or cut back on activities that you enjoyed just so you could drink?
- Gotten into dangerous situations while drinking or after drinking? Some examples are driving drunk and having unsafe sex.
- Kept drinking even though it was making you feel depressed or anxious? Or when it was adding to another health problem?
- Had to drink more and more to feel the effects of the alcohol?
- Had withdrawal symptoms when the alcohol was wearing off? They include trouble sleeping, shakiness, irritability, anxiety, depression, restlessness, nausea, and sweating. In severe cases, you could have a fever, seizures, or hallucinations.
If you have any of these symptoms, your drinking may already be a cause for concern. The more symptoms you have, the more serious the problem is.
If you think you might have an AUD, see your health care provider for an evaluation. Your provider can help make a treatment plan, prescribe medicines, and if needed, give you treatment referrals.
It sits within Substance Use and Disorders.
The lead U.S. institute for this subject is the National Institute on Alcohol Abuse and Alcoholism.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Alcohol Use Disorder (AUD)
209 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- TRIS: Contingency Management App for Alcohol Use DisorderUniversity of Sao Paulo General Hospital
- Pregnenolone Treatment for Alcohol Use Disorder and Major Depressive DisorderSherwood Brown, MD, PhD
- Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Pomegranate Dietary Supplements in AUD and ALDUniversity of Louisville
- Acceptability and Feasibility Study of Non-alcoholic BeveragesStanford University
- Intervention for Alcohol Use Disorder Recovery After Liver TransplantationLeigh Anne Dageforde
Research already completed
- Brain Inflammation and Function in AlcoholismNational Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Oxytocin to Enhance Integrated Treatment for AUD and PTSDMedical University of South Carolina
- Feasibility and Effects of Activity Trackers Among Alcohol Users Receiving In-patient Treatment for Alcohol Use DisorderUniversity of Oviedo
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- How Many Is Too Many? When Drinking Becomes a ProblemNational Institutes of Health
- Rethinking Drinking: Questions and AnswersNational Institute on Alcohol Abuse and Alcoholism
- Understanding Alcohol Use DisorderNational Institute on Alcohol Abuse and Alcoholism
Symptoms
- What Are Symptoms of Alcohol Use Disorder?National Institute on Alcohol Abuse and Alcoholism
Diagnosis and Tests
- Alcohol Use Screening TestsNational Library of Medicine
- Blood Alcohol LevelNational Library of Medicine
- Gamma-glutamyl Transferase (GGT) TestNational Library of Medicine
Treatments and Therapies
- Alcohol Use Disorder (AUD) Treatment: MedlinePlus Health TopicNational Library of Medicine
- NIAAA Alcohol Treatment NavigatorNational Institute on Alcohol Abuse and Alcoholism
Prevention and Risk Factors
- Understanding Alcohol Drinking PatternsNational Institute on Alcohol Abuse and Alcoholism
Living With
- Alcohol Use in FamiliesAmerican Academy of Child and Adolescent Psychiatry
- Intervention: Help a Loved One Overcome AddictionMayo Foundation for Medical Education and Research
- Support Strategies for QuittingNational Institute on Alcohol Abuse and Alcoholism
Related Issues
- Alcohol Associated Liver DiseaseAmerican Liver Foundation
- Alcohol PoisoningMayo Foundation for Medical Education and Research
- Alcohol's Effects on the BodyNational Institute on Alcohol Abuse and Alcoholism
- Alcohol-Related BlackoutsNational Institutes of Health
- Drink Less, Be Your BestCenters for Disease Control and Prevention
- PTSD and Problems with Alcohol UseNational Center for PTSD
- Wernicke-Korsakoff SyndromeNational Institute on Alcohol Abuse and Alcoholism
Genetics
- Alcohol use disorder: MedlinePlus GeneticsNational Library of Medicine
Statistics and Research
- Alcohol Facts and StatisticsNational Institute on Alcohol Abuse and Alcoholism
Clinical Trials
- ClinicalTrials.gov: Alcohol Use Disorder (AUD)National Institutes of Health
- ClinicalTrials.gov: Binge DrinkingNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Alcoholism. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Alcohol Use Disorder (AUD), a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.