Also called: Pertussis
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Whooping Cough
Whooping cough, or pertussis, is a respiratory infection that can cause coughing fits. In serious cases, the coughing can become violent and rapid. You may cough so hard that you vomit. The name of the disease comes from the whooping noise you might make when you try to breathe in after coughing.
Whooping cough is very contagious and can affect anyone. But it can be especially serious in babies who did not yet get the vaccine. About half of babies under age one who get whooping cough need care in the hospital.
Whooping cough is caused by a type of bacteria called Bordetella pertussis. It spreads from person to person. People who have pertussis usually spread it through coughing, sneezing, or breathing very close to someone. It can also sometimes be spread by touching an infected surface and then touching your nose or mouth.
If you get pertussis, you are contagious for about 2 weeks after you start coughing. Antibiotics may shorten the time that you are contagious.
The symptoms of pertussis usually start within 5 to 10 days after you are exposed. But sometimes you may not get symptoms until up to 3 weeks later.
Whooping cough usually starts with cold-like symptoms. They may last for 1 to 2 weeks and can include:
- Runny nose
- Mild fever
- Mild, occasional cough
The early symptoms in babies can be different. They may only cough a little bit, or they may not cough at all. Babies may have apnea, which means that there is a pause in breathing. They may start to turn blue. If this happens, get medical care for your baby right away.
As whopping cough gets worse, the symptoms may include:
- Fits of many, rapid coughs followed by a high-pitched "whoop" sound
- Vomiting during or after coughing fits
- Exhaustion after coughing fits
The coughing fits get worse and start happening more often, especially at night. You may have them for up to 10 weeks or more.
Recovery from this can happen slowly. Your cough gets milder and happens less often. The coughing fits can come back if you have another respiratory infection, even months after you first got whooping cough.
Your health care provider may use many tools to diagnose whooping cough:
- A medical history, which includes asking about your symptoms
- A physical exam
- A lab test which involves taking a sample of mucus from the back of the throat through the nose. This may be done with a swab or syringe filled with saline. The sample is tested for the bacteria that causes whooping cough.
- Blood test
- Chest x-ray
The treatment for whooping cough is usually antibiotics. Early treatment is very important. It may make your infection less serious and can also help prevent spreading the disease to others.
Treatment after you have been sick for 3 weeks or longer may not help. The bacteria are gone from your body by then, even though you usually still have symptoms. This is because the bacteria have already done damage to your body.
Whooping cough can sometimes be very serious and require treatment in the hospital.
Vaccines are the best way to prevent whooping cough. There are two vaccines in the United States that can help prevent whooping cough: DTaP and Tdap. These vaccines also provide protection against tetanus and diphtheria.
Babies and other people at high risk serious disease should be kept away from people who have whooping cough.
Sometimes health care providers give antibiotics to family members of people who have had whooping cough or people who have been exposed to it. The antibiotics may prevent them from getting the disease.
You may also help prevent the spread of whooping cough (and other respiratory diseases) by:
- Washing your hands often with soap and water. You can use an alcohol-based hand rub if soap and water are not available.
- Avoiding touching your face with unwashed hands
- Cleaning and disinfecting surfaces that you frequently touch, including toys
- Covering coughs and sneezes with a tissue or upper shirt sleeve, not hands
- Staying home when sick
- Avoiding close contact with people who are sick
Centers for Disease Control and Prevention
It sits within Children and Teenagers, Infections and Lungs and Breathing.
The lead U.S. institute for this subject is the National Institute of Allergy and Infectious Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Whooping Cough
415 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- A Study on the Immune Response and Safety of a Combined Vaccine Against Diphtheria, Tetanus and Acellular Pertussis (dTpa) in Healthy Japanese Adolescents Aged 11 Years to <13 YearsGlaxoSmithKline
- A Study on the Immune Response and Safety of a Combined Vaccine Against Diphtheria, Tetanus and Acellular Pertussis (dTpa) in Japanese Healthy Pregnant WomenGlaxoSmithKline
- Concurrent Versus Sequential Administration of Tdap and RSV Vaccines in PregnancyCanadian Immunization Research Network
- Maternal Immunization With Tetanus Toxoid, Reduced Diphtheria Toxoid, Reduced-dose (2 µg) Recombinant Pertussis Vaccine (TdaP2gen) and Its Effect on the Immune Response in Thai Infants up to 15-18 Months OldChiang Mai University
- Periscope Phase C Bordetella Pertussis Human Challenge Study With Delayed Antibiotic Therapy for 6 WeeksUniversity of Southampton
- A Phase 4, Randomised Vaccination Study in Healthy Adults to Investigate the Effects of Acellular Pertussis Vaccine on Colonisation With Bordetella Pertussis Using Controlled Human InfectionDimitri Diavatopoulos
Research already completed
- Tdap Vaccination During Pregnancy or Postpartum and Lactation-Related OutcomesHealthPartners Institute
- Safety and Immunogenicity Study of Tdap Vaccinations for Plasma DonorsABO Holdings, Inc.
- Clinical Study to Assess the Immunogenicity and Safety of Hexavalent Vaccine Containing Reduced Dose IPVSerum Institute of India Pvt. Ltd.
- Evaluation of a Tdap-IPV (Tetanus, Diphteria, Pertussis and Inactivated Polio) Vaccination Remedial Strategy on Vaccination Coverage in Patients 65 Years of Age or OlderCentre Hospitalier le Mans
- Establishing a Controlled Human Infection Model of Bordetella PertussisDalhousie University
- Pertussis Vaccination Among HIV-infected and HIV-uninfected Pregnant WomenFarzanah Laher
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- About Whooping Cough (Pertussis)Centers for Disease Control and Prevention
- Pertussis (Whooping Cough)Centers for Disease Control and Prevention
- Whooping Cough (Pertussis)Nemours Foundation
Symptoms
- Symptoms of Whooping CoughCenters for Disease Control and Prevention
Diagnosis and Tests
- Nasal SwabNational Library of Medicine
- Whooping Cough TestsNational Library of Medicine
Treatments and Therapies
- Treatment of Whooping CoughCenters for Disease Control and Prevention
Prevention and Risk Factors
- Tetanus, Diphtheria, and Pertussis Vaccines: MedlinePlus Health TopicNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: Whooping CoughNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Whooping Cough. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Whooping Cough, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.