Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Uterine Diseases
The uterus, or womb, is the place where a fetus grows during pregnancy. Uterine diseases are conditions that affect the uterus. These diseases can be benign (not cancer) or malignant (cancerous). They may affect your menstrual periods, your ability to get pregnant, or the health of your reproductive organs.
Some types of uterine diseases include:
- Adenomyosis. Tissue that usually lines the uterus grows on the outside walls.
- Cervicitis. Swelling or inflamed tissue of the cervix. The cervix is the lower part of the uterus.
- Endometrial hyperplasia. An overgrowth of normal cells inside the uterus.
- Endometriosis. Tissue like the lining of the uterus grows in other places in your body.
- Uterine prolapse. The uterus drops in to the vagina due to weakened pelvic muscles. This can happen after a few vaginal births, menopause, or because of obesity.
Various factors can cause uterine diseases. These can include hormonal imbalances, thyroid problems, fibroids, polyps, cancer, infection, or pregnancy.
Your symptoms will depend on the type of uterine condition you have. The first sign of a problem with the uterus may be abnormal bleeding. Bleeding could occur between periods, be very heavy, or last much longer than usual. Other symptoms may include bleeding after sex or pelvic pain.
To find out the cause of your symptoms, your health care provider may:
- Ask about your symptoms and medical history
- Do a pelvic exam
- Order blood tests or imaging tests
- Do a biopsy
Treatment depends on the cause. It may include pain medicine, hormone therapy, or surgery. Your provider will work with you to choose the best treatment.
It sits within Women and Female Reproductive System.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Uterine Diseases
5,494 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or CarcinosarcomaNational Cancer Institute (NCI)
- Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)National Cancer Institute (NCI)
- A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix CancerGOG Foundation
- Comprehensive Evaluation of Tumor Oxygenation, Metabolism and Blood Supply of High Grade Glioma and Cervical Cancers Using Dynamic FAZA PET and Multiparametric MRM.D. Anderson Cancer Center
- Evaluating the Addition of OK-1 Weekly Paclitaxel in Patients With Endometrial CancerUniversity of Oklahoma
- Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer SurvivorsUniversity of Southern California
Research already completed
- A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial CarcinomaM.D. Anderson Cancer Center
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Uterine ConditionsMarch of Dimes Foundation
Diagnosis and Tests
- Hysterosalpingography (Uterosalpingography)Radiological Society of North America
- HysteroscopyNational Library of Medicine
- LaparoscopyNational Library of Medicine
- Pelvic ExamMayo Foundation for Medical Education and Research
- Pelvis UltrasoundRadiological Society of North America
Treatments and Therapies
- Dilation and Curettage (D&C)Mayo Foundation for Medical Education and Research
Genetics
- Mayer-Rokitansky-Küster-Hauser syndrome: MedlinePlus GeneticsNational Library of Medicine
- Müllerian aplasia and hyperandrogenism: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: Uterine DiseasesNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Uterine Diseases. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Uterine Diseases, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.