Health Topic

Tuberculosis

Tuberculosis (TB) is a disease caused by bacteria that usually attack the lungs. Skin tests, blood tests, and x-rays can tell if you have TB. Learn more.

Reviewed Reviewed by a registered pharmacistGeneral information

Also called: TB

Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.

About Tuberculosis

Tuberculosis (TB) is a bacterial disease that usually attacks the lungs. But it can also attack other parts of the body, including the kidneys, spine, and brain.

Not everyone infected with TB bacteria (germs) becomes sick. So, there are two types of TB conditions:

  • Inactive (latent) TB infection, where the TB germs live in your body but don't make you sick.
  • TB disease (active TB) where you get sick from the TB germs. TB disease can almost always be cured with antibiotics. But if it's not treated properly, it can be fatal.

TB is found in the U.S., but it is more common in certain other countries.

TB is caused by bacteria (germs) called Mycobacterium tuberculosis. The germs spread from person to person through the air. People who have TB disease in their throat or lungs spread the germs in the air when they cough, sneeze, talk, or sing. If you breathe in the air that has the germs, you can get TB.

TB is not spread by touching, kissing, or sharing food or dishes.

You're more likely to catch TB from people you live or work with than from people you see for shorter amounts of time.

Anyone who is near a person with TB disease can get infected with the germs. You are more likely to be near someone with TB disease if you:

  • Were born in or often travel to countries where TB disease is common
  • Are a health care worker
  • Work or live in a place where TB is more common, such as shelters for people without homes, jails, and nursing homes

Certain people are more likely to get sick with TB disease after they get infected. They include people who:

  • Have HIV
  • Became infected with TB in the last 2 years
  • Have other diseases, such as diabetes, that make it hard for your body to fight TB germs
  • Have alcohol use disorder (AUD) or inject illegal drugs
  • Were not treated correctly for TB in the past
  • Are under age 5
  • Are an older adult
  • Take medicines that weaken the immune system, such as medicines taken after an organ transplant, steroids, and specialized treatments for certain autoimmune diseases

Most people who have TB germs in their bodies don't get sick with TB disease. Instead, they have inactive TB infection. With an inactive TB infection, you:

  • Don't have symptoms
  • Can't spread TB to others
  • Could get sick with active TB disease in the future if your immune system becomes weak for another reason
  • Need to take medicine to prevent getting sick with active TB disease in the future

If you have TB disease, the TB germs are active, meaning that they are growing (multiplying) inside your body and making you sick. If the TB is growing in your lungs or throat, you can spread the TB germs to other people. You can get sick with TB disease weeks to years after you're infected with TB germs.

With TB disease, your symptoms will depend on where the TB is growing in your body:

  • General symptoms may include: Chills and fever
  • Night sweats (heavy sweating during sleep)
  • Losing weight without trying
  • Loss of appetite
  • Weakness or fatigue
  • A cough that lasts longer than 3 weeks
  • Coughing up blood or sputum (a thick mucus from the lungs)
  • Chest pain

Your health care provider or your local health department can test you to find out if you have TB germs in your body. They will give you either a TB skin or blood test.

If your test shows that you have TB germs, you'll need to have other tests to see if the germs are actively growing:

  • Tests for TB disease in the lungs usually include testing samples of your sputum and having chest x-rays.
  • Tests for TB disease in other parts of your body may include tests of urine and tissue samples.

You may need a TB test if you have symptoms of TB disease or if you are at high risk because you are more likely to be near someone with TB disease.

People who have HIV also need to get tested for TB. HIV weakens your immune system. So if you have both HIV and inactive TB, the TB can quickly become active TB disease. You will need treatment for the inactive TB as soon as possible to prevent active TB disease.

The treatment for both inactive TB infection and TB disease is antibiotics. To make sure you get rid of all the TB germs in your body, it's very important to follow the directions for taking your medicine.

If you don't follow the directions, the TB germs in your body could change and become antibiotic resistant. That means the medicine may stop working and your TB may become hard to cure.

  • For inactive TB infections, you need to take medicines for three, four, six, or nine months, depending on the treatment plan. Treatment helps make sure you don't get TB disease in the future.
  • For active TB disease, you usually need to take medicines for four, six, or nine months, depending on the treatment plan. Treatment will almost always cure you if you take your pills the right way.
  • For TB disease in your lungs or throat, you'll need to stay home for a few weeks, so you don't spread disease to other people. You can protect the people you live with by: Covering your nose and mouth.
  • Opening windows when possible.
  • Not getting too close to them.

By following medical advice for TB testing and treatment, you can keep yourself healthy and help stop the spread of TB.

Centers for Disease Control and Prevention

It sits within Infections and Lungs and Breathing.

The lead U.S. institute for this subject is the National Institute of Allergy and Infectious Diseases.

When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.

Research on Tuberculosis

1,649 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.

What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.

Research currently under way

Research already completed

Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.

Where to read more

Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.

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Symptoms

Diagnosis and Tests

Treatments and Therapies

Prevention and Risk Factors

Related Issues

Statistics and Research

Clinical Trials

Medical subject headings

Clinicians and researchers index this subject under Tuberculosis, Tuberculosis, Pulmonary. These are the terms to use when searching medical literature.

This page is built from the MedlinePlus health topic record for Tuberculosis, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.