Also called: Cavities · Dental caries
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Tooth Decay
Tooth decay is damage to a tooth's surface, or enamel. It happens when bacteria in your mouth make acids that attack the enamel. Tooth decay can lead to cavities (dental caries), which are holes in your teeth. If tooth decay is not treated, it can cause pain, infection, and even tooth loss.
Our mouths are full of bacteria. Some bacteria are helpful. But some can be harmful, including the ones that play a role in tooth decay. These bacteria combine with food to form a soft, sticky film called plaque. The bacteria in plaque use the sugar and starch in what you eat and drink to make acids. The acids begin to eat away at the minerals on your enamel. Over time, the plaque can harden into tartar. Besides damaging your teeth, plaque and tartar can also irritate your gums and cause gum disease.
You get fluoride from toothpaste, water, and other sources. This fluoride, along with your salvia, helps the enamel repair itself by replacing the minerals. Your teeth go through this natural process of losing minerals and regaining minerals all day long. But if you don't take care of your teeth and/or you eat and drink lots of sugary or starchy things, your enamel will keep losing minerals. This leads to tooth decay.
A white spot may appear where minerals have been lost. This is an early sign of tooth decay. You may be able to stop or reverse the decay at this point. Your enamel can still repair itself, if you take better care of your teeth and limit sugary/starchy foods and drinks.
But if the tooth decay process continues, more minerals are lost. Over time, the enamel is weakened and destroyed, forming a cavity. A cavity is a hole in your tooth. It is permanent damage that a dentist has to repair with a filling.
The main risk factors for tooth decay are not taking care of your teeth and having too many sugary or starchy foods and drinks.
Some people have a higher risk of tooth decay, including people who:
- Don't have enough saliva, because of medicines, certain diseases, or some cancer treatments
- Don't get enough fluoride
- Are very young. Babies and toddlers who drink from bottles are at risk, especially if they are given juice or get bottles at bedtime. This exposes their teeth to sugars for long periods of time.
- Are older. Many older adults have receding gums and more wear on their teeth. These raise the risk of decay on the exposed root surfaces of their teeth.
In early tooth decay, you usually don't have symptoms. As tooth decay gets worse, it can cause:
- A toothache (tooth pain)
- Tooth sensitivity to sweets, hot, or cold
- White or brown stains on the surface of a tooth
- A cavity
- An infection, which can lead to an abscess (pocket of pus) forming. The abscess can cause pain, facial swelling, and fever.
Dentists usually find tooth decay and cavities by looking at your teeth and probing them with dental instruments. Your dentist will also ask if you have any symptoms. Sometimes you may need a dental x-ray.
There are several treatments for tooth decay and cavities. Which treatment you get depends on how bad the problem is:
- Fluoride treatments. If you have early tooth decay, a fluoride treatment can help the enamel to repair itself.
- Fillings. If you have a typical cavity, your dentist will remove the decayed tooth tissue and then restore the tooth by filling it with a filling material.
- Root canal. If the damage to the tooth and/or an infection spreads to the pulp (inside of the tooth), you might need a root canal. Your dentist will remove the decayed pulp and clean inside the tooth and root. The next step is to fill the tooth with a temporary filling. Then you will need to come back to get a permanent filling or a crown (a cover on the tooth).
- Extraction (pulling the tooth). In the most severe cases, when the damage to the pulp cannot be fixed, your dentist may pull the tooth. Your dentist will suggest that you get a bridge or implant to replace the missing tooth. Otherwise, the teeth next to the gap may move over and change your bite.
There are steps that you can take to prevent tooth decay:
- Make sure that you get enough fluoride by Brushing with a fluoride toothpaste
- Drinking tap water with fluoride. Most bottled water does not contain fluoride.
- Using fluoride mouth rinse
It sits within Mouth and Teeth.
The lead U.S. institute for this subject is the National Institute of Dental and Craniofacial Research.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Tooth Decay
1,140 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Clinical Performance of Two HEMA-Free Universal Adhesive SystemsCairo University
- Comparing Two Brands of Silver Diamine Fluoride for Stopping Cavities in ChildrenNational Research Centre, Egypt
- Correlation Between Colour of Defect and Enamel Breakdown in First Permanent Molars With Molar Incisor Hypomineralisation (MIH)University of Basel
- Caries of First Permanent Molars and Association With Dietary and Oral Habits Among a Group of Egyptian ChildrenOctober University for Modern Sciences and Arts
- Clinical Evaluation of the Retention of Fissure Sealants Applied Following Guided Biofilm Therapy and Conventional PolishingMarmara University
- Birth to Three - Cavity FreeUniversity of Iowa
Research already completed
- Effects of Calcium-Containing Oral Sprays on Fluorescence-Detectable Plaque Area in ChildrenTri-Service General Hospital (TSGH)
- Effect of Different Heating Protocols of Resin Composites on Pulp Condition (Randomized Controlled Trial)Ain Shams University
- Children's Comfort With Isolite and Rubber Dam During Dental TreatmentCumhuriyet University
- A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifrices in Comparison With 0.24% Sodium Fluoride (1100 Ppm F) Dentifrice Control in 10 to 14-year-old ChildrenColgate Palmolive
- CARIES ARREST USING SILVER DIAMINE FLUORIDE VERSUS FISSURE SEALANT IN OCCLUSAL DENTAL CARIOUS LESIONSCairo University
- Orthodontic Varnish Microbiology StudyUniversity of California, Los Angeles
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Cavities and Tooth DecayMayo Foundation for Medical Education and Research
- Tooth DecayNational Institute of Dental and Craniofacial Research
Diagnosis and Tests
- Dental ExamNational Library of Medicine
Treatments and Therapies
- Dental Amalgam FillingsFood and Drug Administration
- Dental FillingsNational Institute of Dental and Craniofacial Research
Prevention and Risk Factors
- About Community Water FluoridationCenters for Disease Control and Prevention
- About FluorideCenters for Disease Control and Prevention
- Dental SealantsNational Institute of Dental and Craniofacial Research
- Fluoride & Dental HealthNational Institute of Dental and Craniofacial Research
Related Issues
- Story of FluoridationNational Institute of Dental and Craniofacial Research
Statistics and Research
- Dental Caries (Tooth Decay)National Institute of Dental and Craniofacial Research
- Dental SealantsNational Institute of Dental and Craniofacial Research
- Water Fluoridation Data and StatisticsCenters for Disease Control and Prevention
Clinical Trials
- ClinicalTrials.gov: Dental CariesNational Institutes of Health
- ClinicalTrials.gov: Dental PlaqueNational Institutes of Health
- ClinicalTrials.gov: Pit and Fissure SealantsNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Dental Caries. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Tooth Decay, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.