Also called: Gastric cancer
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Stomach Cancer
The stomach is an organ between the esophagus and the small intestine. It mixes food with stomach acid and helps digest protein. Stomach cancer mostly affects older people - two-thirds of people who have it are over age 65. Your risk of getting it is also higher if you:
- Have had a Helicobacter pylori infection
- Have had stomach inflammation
- Are a man
- Eat lots of salted, smoked, or pickled foods
- Smoke cigarettes
- Have a family history of stomach cancer
It is hard to diagnose stomach cancer in its early stages. Indigestion and stomach discomfort can be symptoms of early cancer, but other problems can cause the same symptoms. In advanced cases, there may be blood in your stool, vomiting, unexplained weight loss, jaundice, or trouble swallowing. Doctors diagnose stomach cancer with a physical exam, blood and imaging tests, an endoscopy, and a biopsy.
Because it is often found late, it can be hard to treat stomach cancer. Treatment options include surgery, chemotherapy, radiation or a combination.
It sits within Cancers and Digestive System.
The lead U.S. institute for this subject is the National Cancer Institute.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Stomach Cancer
4,271 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)National Cancer Institute (NCI)
- Testing Trastuzumab and Pertuzumab in Patients With Higher Than Normal Copies of the HER2 Gene Found in Their Tumors (MATCH - Subprotocol J)National Cancer Institute (NCI)
- Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic CancerAulos Bioscience, Inc.
- Berzosertib and Irinotecan in Treating Patients With Progressive, Metastatic, or Unresectable TP53 Mutant Gastric or Gastroesophageal Junction CancerNational Cancer Institute (NCI)
- Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced CancersArcus Biosciences, Inc.
- Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)EMD Serono Research & Development Institute, Inc.
Research already completed
- Study of Oxaliplatin and Xeloda and Cetuximab as First Line Treatment for Metastatic or Unresectable Gastric or Gastroesophageal Junction CancerUniversity of Southern California
- Esophageal Cancer Genetics StudiesNational Cancer Institute (NCI)
- Development of a Multimodal AI System for GIST ManagementQun Zhao
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Stomach CancerAmerican Cancer Society
Symptoms
- Stomach Cancer SymptomsNational Cancer Institute
Diagnosis and Tests
- Stomach Cancer DiagnosisNational Cancer Institute
- Stomach Cancer ScreeningNational Cancer Institute
- Stomach Cancer StagesNational Cancer Institute
- Tests for Stomach CancerAmerican Cancer Society
Treatments and Therapies
- Drugs Approved for Stomach (Gastric) CancerNational Cancer Institute
- Gastrectomy - seriesMedical Encyclopedia
- Stomach Cancer TreatmentNational Cancer Institute
- Stomach Cancer Treatment by StageNational Cancer Institute
- Surgery for Stomach CancerAmerican Cancer Society
Prevention and Risk Factors
- Risk Factors for Stomach CancerAmerican Cancer Society
- Stomach Cancer Causes and Risk FactorsNational Cancer Institute
- Stomach Cancer Causes, Risk Factors, and PreventionAmerican Cancer Society
Living With
- After Stomach Cancer TreatmentAmerican Cancer Society
- Coping with Stomach CancerNational Cancer Institute
Related Issues
- Helicobacter pylori (H. pylori) and CancerNational Cancer Institute
- Stomach PolypsMayo Foundation for Medical Education and Research
Genetics
- Hereditary diffuse gastric cancer: MedlinePlus GeneticsNational Library of Medicine
Statistics and Research
- Cancer Statistics: Cancer of the StomachNational Cancer Institute
- Incidence of Cancers of the Lower Stomach Increasing among Younger AmericansNational Cancer Institute
- Key Statistics about Stomach CancerAmerican Cancer Society
- Pembrolizumab Secures FDA Approval in Stomach CancerNational Cancer Institute
Clinical Trials
- ClinicalTrials.gov: Stomach NeoplasmsNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Stomach Neoplasms. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Stomach Cancer, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.