Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Sprains and Strains
A sprain is a stretched or torn ligament. Ligaments are tissues that connect bones at a joint. Falling, twisting, or getting hit can all cause a sprain. Ankle and wrist sprains are common. Symptoms include pain, swelling, bruising, and being unable to move your joint. You might feel a pop or tear when the injury happens.
A strain is a stretched or torn muscle or tendon. Tendons are tissues that connect muscle to bone. Twisting or pulling these tissues can cause a strain. Strains can happen suddenly or develop over time. Back and hamstring muscle strains are common. Many people get strains playing sports. Symptoms include pain, muscle spasms, swelling, and trouble moving the muscle.
At first, treatment of both sprains and strains usually involves resting the injured area, icing it, wearing a bandage or device that compresses the area, and medicines. Later treatment might include exercise and physical therapy.
It sits within Bones, Joints and Muscles and Injuries and Wounds.
The lead U.S. institute for this subject is the National Institute of Arthritis and Musculoskeletal and Skin Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Sprains and Strains
811 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Compare the Effect of Radiofrequency (TECAR) and Ultrasound on Sensation, Hand Dexterity, and Quality of Life in Patients With Carpal Tunnel Syndrome.Delta University for Science and Technology
- The Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training in Chronic Ankle InstabilityBahçeşehir University
- Effectiveness of Amniotic Membrane Combined With Secretome as an Adjunct to Carpal Tunnel Release Surgery: Evaluation Using the Boston Carpal Tunnel Questionnaire and ElectromyographyPT. Prodia Stem Cell Indonesia
- 124I-Evuzamitide PET/CT Imaging In Patients With Lumbar Spinal Stenosis and Carpal Tunnel SyndromeUniversity of Tennessee Graduate School of Medicine
- Photobiomodulation for Median Nerve Neuroplasticity in Carpal Tunnel Syndrome: A Randomized Controlled TrialUniversity of Lahore
- Reliability and Validity of Hand Function Tests in Carpal Tunnel SyndromeIzmir Bakircay University
Research already completed
- Turkish Adaptation of the CTS-6 Evaluation Tool: A Validation and Reliability StudyIstanbul University
- Effects of Whole Wrist Versus Specific Carpal Bone Mobilization in the Patients of Carpel Tunnel SyndromeRiphah International University
- Comparison of Injection Techniques in Carpal Tunnel SyndromeAnkara Etlik City Hospital
- FIFA 11+ Warm-Up and Injury Risk Classification in Youth Amateur Soccer PlayersPamukkale University
- Conventional, High-Intensity Laser, and Magnetic Field Therapies in Carpal Tunnel SyndromeKTO Karatay University
- The Effect of Capacitive and Resistive Electrical Transfer Therapy on Hamstring InjuriesHacettepe University
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- SprainsMayo Foundation for Medical Education and Research
Diagnosis and Tests
- Musculoskeletal MRIRadiological Society of North America
- Musculoskeletal UltrasoundRadiological Society of North America
Treatments and Therapies
- How to Care for a Sprained AnkleAmerican Orthopaedic Foot and Ankle Society
- Strains and SprainsNemours Foundation
Prevention and Risk Factors
- Stretching: Focus on FlexibilityMayo Foundation for Medical Education and Research
Living With
- How to Strengthen Your Ankle after a SprainAmerican Orthopaedic Foot and Ankle Society
- How to Stretch Your Ankle after a SprainAmerican Orthopaedic Foot and Ankle Society
- Mobility Aids: MedlinePlus Health TopicNational Library of Medicine
Related Issues
- Sports InjuriesNational Institute of Arthritis and Musculoskeletal and Skin Diseases
Clinical Trials
- ClinicalTrials.gov: Sprains and StrainsNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Sprains and Strains. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Sprains and Strains, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.