Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Spine Injuries and Disorders
Your backbone, or spine, is made up of 26 bone discs called vertebrae. The vertebrae protect your spinal cord and allow you to stand and bend. A number of problems can change the structure of the spine or damage the vertebrae and surrounding tissue. They include:
- Infections
- Injuries
- Tumors
- Conditions, such as ankylosing spondylitis and scoliosis
- Bone changes that come with age, such as spinal stenosis and herniated disks
Spinal diseases often cause pain when bone changes put pressure on the spinal cord or nerves. They can also limit movement. Treatments differ by disease, but sometimes they include back braces and surgery.
It sits within Bones, Joints and Muscles.
The lead U.S. institute for this subject is the National Institute of Arthritis and Musculoskeletal and Skin Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Spine Injuries and Disorders
161 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Evaluating the Efficacy of a Mobile Application in Postoperative RehabilitationYale University
- Brain Controlled Spinal Cord Stimulation In Participants With Spinal Cord Injury For Lower Limb RehabilitationEcole Polytechnique Fédérale de Lausanne
- The Ailliance Post-Market Clinical StudyMedtronic Spinal and Biologics
- Evaluation of Osteopathic Protocol on Rachialgia, BisCabinet d'ostéopathie Michel Boeuf
- Evaluation of the Evolution of Patient Care Within the Spinal Pathology DepartmentUniversity Hospital, Bordeaux
- Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine MetastasesHenry Ford Health System
Research already completed
- Establishing a Descriptive Cohort of Patients Cared for Operation on the SpineCentre Hospitalier Universitaire de Nīmes
- Effectiveness of a Quick Release Dynamic Muscle-strengthening Program on Dynamic Stabilization of the Cervical SpineUniversity Hospital, Montpellier
- Dynamic Compliance-Guided Ventilation in Lumbar SurgeryAnkara City Hospital Bilkent
- Local Anesthetic Infiltration to Prevent Postoperative Pain After Lumbar SurgeryUniversity Hospital, Bordeaux
- Inter-semispinal Fascial Plane Block (ISPB) Versus Erector Spinae Plane Block (ESPB) in Posterior Cervical Spine SurgeryFayoum University
- Virtual Intervention for Vertebral frActure: a Pilot, Feasibility Study for a Multicentre Randomized Controlled TrialUniversity of Waterloo
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Diagnosis and Tests
- CT Scan of the SpineRadiological Society of North America
- Electromyography (EMG) and Nerve Conduction StudiesNational Library of Medicine
- Lumbar and Cervical DiscographyNorth American Spine Society
- Spine MRIRadiological Society of North America
Treatments and Therapies
- About NeurointerventionsSociety of NeuroInterventional Surgery
- Artificial Disc Replacement (ADR)North American Spine Society
- Back Surgery: When Is It a Good Idea?Mayo Foundation for Medical Education and Research
- Chiropractic: MedlinePlus Health TopicNational Library of Medicine
- Epidural InjectionsRadiological Society of North America
- Laparoscopic Spine SurgerySociety of American Gastrointestinal and Endoscopic Surgeons
- Lumbar (Open) Microscopic DiscectomyNorth American Spine Society
Prevention and Risk Factors
- Getting It Straight: Improve Your Posture for Better HealthNational Institutes of Health
Living With
- Spine Rehabilitation ExercisesAmerican Academy of Orthopaedic Surgeons
Related Issues
- Degenerative Changes in the Spine: Is This Arthritis?Mayo Foundation for Medical Education and Research
- Depression and Spinal Cord Injuries and Disorders (SCI/D)Department of Veterans Affairs
Genetics
- Intervertebral disc disease: MedlinePlus GeneticsNational Library of Medicine
- Spondylocostal dysostosis: MedlinePlus GeneticsNational Library of Medicine
- Spondylothoracic dysostosis: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: Fractures, CompressionNational Institutes of Health
- ClinicalTrials.gov: KyphosisNational Institutes of Health
- ClinicalTrials.gov: Spinal DiseasesNational Institutes of Health
- ClinicalTrials.gov: Spinal FracturesNational Institutes of Health
- ClinicalTrials.gov: Spinal InjuriesNational Institutes of Health
- ClinicalTrials.gov: SpondylolisthesisNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Spinal Fractures, Spinal Injuries, Spinal Diseases. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Spine Injuries and Disorders, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.