Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Spinal Cord Diseases
Your spinal cord is a bundle of nerves that runs down the middle of your back. It carries signals back and forth between your body and your brain. It is protected by your vertebrae, which are the bone disks that make up your spine. If you have an accident that damages the vertebrae or other parts of the spine, this can also injure the spinal cord. Other spinal cord problems include:
- Tumors
- Infections such as meningitis and polio
- Inflammatory diseases
- Autoimmune diseases
- Degenerative diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy
Symptoms vary but might include pain, numbness, loss of sensation and muscle weakness. These symptoms can occur around the spinal cord, and also in other areas such as your arms and legs. Treatments often include medicines and surgery.
It sits within Brain and Nerves.
The lead U.S. institute for this subject is the National Institute of Neurological Disorders and Stroke.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Spinal Cord Diseases
4,312 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Neuromodulation of the Cortex and Spinal CordFather Flanagan's Boys' Home
- A Real-World Medical Chart Review of Spinal Muscular Atrophy Patients Treated With Onasemnogene Abeparvovec in Saudi ArabiaNovartis Pharmaceuticals
- QCT in ALS Diagnosis, Mechanistic Understanding and Follow-upUniversity Hospital, Clermont-Ferrand
- A Study of SGT-212 Gene Therapy in Friedreich's AtaxiaSolid Biosciences Inc.
- ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)Mayo Clinic
- ZEPU-AI1 Gait Robot Training Study (ZEPUAI1RCT)Bangladesh Medical University
Research already completed
- Trial of Oral Digoxin in Individuals With Amyotrophic Lateral Sclerosis (ALS)Massachusetts General Hospital
- Natural History and Biomarkers of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Caused by the C9ORF72 Gene MutationNational Institute of Neurological Disorders and Stroke (NINDS)
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Brain and Spinal Cord TumorsNational Institute of Neurological Disorders and Stroke
- Overview of Spinal Cord DisordersMerck & Co., Inc.
Diagnosis and Tests
- Cerebrospinal Fluid (CSF) AnalysisNational Library of Medicine
- Lumbar and Cervical DiscographyNorth American Spine Society
- MyelographyNational Library of Medicine
- Neurological ExamNational Library of Medicine
- Specialized Nerve Tests: EMG, NCV and SSEPNorth American Spine Society
- Spine MRIRadiological Society of North America
Treatments and Therapies
- Childhood Central Nervous System Germ Cell Tumors TreatmentNational Cancer Institute
Living With
- Dressing with Ease, Style, and ComfortALS Association
Genetics
- Caudal regression syndrome: MedlinePlus GeneticsNational Library of Medicine
Statistics and Research
- Advances in Brain and Spinal Cord Tumor ResearchNational Cancer Institute
- Key Statistics for Brain TumorsAmerican Cancer Society
Clinical Trials
- ClinicalTrials.gov: Spinal Cord DiseasesNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Spinal Cord Diseases. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Spinal Cord Diseases, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.