Also called: Herpes zoster
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Shingles
Shingles (herpes zoster) is an infection that causes a painful rash. It is caused by the varicella-zoster virus (VZV). This is the same virus that causes chickenpox. After you have chickenpox, the virus stays in your body. It may not cause problems for many years. But as you get older, the virus may become active again and cause shingles.
Shingles is not contagious. You cannot get shingles from someone else. But you can catch chickenpox from someone with shingles if you have direct contact with fluid from their shingles rash.
The risk of spreading the virus is low if the shingles rash is kept covered. People with shingles cannot spread the virus before their rash blisters appear or after the rash crusts.
Anyone who has had chickenpox can get shingles. But the risk of shingles goes up as you get older. Shingles is most common in people over age 50.
People with weakened immune systems are at higher risk of getting shingles. This includes those who:
- Have immune system diseases such as HIV
- Have certain cancers
- Take medicines that weaken their immune system, such as steroids and medicines you take after an organ transplant
Your immune system may be weaker when you have an infection or are stressed. This can raise your risk of shingles.
It is rare, but possible, to get shingles more than once.
Early signs of shingles include burning or shooting pain and tingling or itching. It is usually on one side of the body or face. The pain can be mild to severe.
Up to several days later, you will get a rash. It consists of blisters that typically scab over in 7 to 10 days. The rash is usually a single stripe around either the left or the right side of the body. In other cases, the rash is only on one side of the face. In rare cases (usually among people with weakened immune systems), the rash may be more widespread. It might look similar to a chickenpox rash.
Some people may also have other symptoms:
- Fever
- Headache
- Chills
- Upset stomach
Shingles can cause other problems (complications):
- Postherpetic neuralgia (PHN) is the most common complication of shingles. It causes severe pain in the areas where you had the shingles rash. It usually gets better in a few weeks or months. But some people can have pain from PHN for many years, and it can interfere with daily life.
- Vision loss can happen if shingles affects your eye. It may be temporary or permanent.
- Hearing or balance problems are possible if you have shingles within or near your ear. You may also have weakness of the muscles on that side of your face. These problems can be temporary or permanent.
Very rarely, shingles can also lead to pneumonia, brain inflammation (encephalitis), or death.
Usually your health care provider can diagnose shingles by taking your medical history and looking at your rash. In some cases, your provider may scrape off tissue from the rash or swab some fluid from the blisters and send the sample to a lab for testing.
There is no cure for shingles. Antiviral medicines may help to make the attack shorter and less severe. They may also help prevent PHN. The medicines are most effective if you can take them within 3 days after the rash appears. So if you think you might have shingles, contact your provider as soon as possible.
Pain relievers may also help with the pain. A cool washcloth, calamine lotion, and oatmeal baths may help relieve some of the itching.
There is a vaccine, called Shingrix, to help prevent shingles and its complications. The Centers for Disease Control and Prevention recommends that healthy adults 50 years and older get the vaccine. Your provider might also recommend the vaccine if you are over 19 and have a weakened immune system. The vaccine is given in two doses.
If you have shingles, you can help prevent spreading the virus to others by:
- Staying away from: People with weakened immune systems
- People who have not had chickenpox or the chickenpox vaccine, especially if they are pregnant
- Premature or low birth weight babies
Centers for Disease Control and Prevention
It sits within Older Adults, Infections, Brain and Nerves and Skin, Hair and Nails.
The lead U.S. institute for this subject is the National Institute of Neurological Disorders and Stroke.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Shingles
508 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control PopulationNational Institute of Allergy and Infectious Diseases (NIAID)
- Midpoint Transverse Process to Pleura (MTP) Block vs Erector Spinae Plane (ESP) Block for Acute Herpes Zoster (HZ) PainTanta University
- A Study Exploring the Effect of Adjuvanted RZV or RSVPreF3 Vaccines on Coronary Plaque Progression in Adults >=50 Years of Age at Risk for Cardiovascular EventsGlaxoSmithKline
- A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Administered as Intramuscular Injection to Healthy Children 15 Months to 6 Years of AgeGlaxoSmithKline
- Subcutaneous Calcitonin in Acute Herpes ZosterTanta University
- Prospective Biological Study to Evaluate the Persistence of COVID-19 Vaccine and Other Vaccines'-Induced Immune Responses in Follicular Lymphoma Patients Undergoing Frontline Induction Immuno-chemotherapy and Anti-CD20 MaintenanceFondazione Italiana Linfomi - ETS
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- About Shingles (Herpes Zoster)Centers for Disease Control and Prevention
- ShinglesNational Institute on Aging
Diagnosis and Tests
- Antibody Serology TestsNational Library of Medicine
- Chickenpox and Shingles TestsNational Library of Medicine
Prevention and Risk Factors
- Shingles VaccinationCenters for Disease Control and Prevention
Genetics
- Shingles: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: Herpes ZosterNational Institutes of Health
- ClinicalTrials.gov: Neuralgia, PostherpeticNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Herpes Zoster. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Shingles, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.