Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Salivary Gland Cancer
Your salivary glands make saliva - sometimes called spit - and empty it into your mouth through openings called ducts. Saliva makes your food moist, which helps you chew and swallow. It helps you digest your food. It also cleans your mouth and contains antibodies that can kill germs.
Salivary gland cancer is a type of head and neck cancer. It is rare. It may not cause any symptoms, or you could notice:
- A lump in your ear, cheek, jaw, lip, or inside the mouth
- Fluid draining from your ear
- Trouble swallowing or opening the mouth widely
- Numbness, weakness, or pain in your face
Doctors diagnose salivary gland cancer using a physical exam, imaging tests, and a biopsy. Treatment can include surgery, radiation therapy, and/or chemotherapy.
It sits within Cancers and Mouth and Teeth.
The lead U.S. institute for this subject is the National Cancer Institute.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Salivary Gland Cancer
451 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate CancerNational Cancer Institute (NCI)
- Testing the Addition of an Anti-cancer Drug, BAY 1895344, With Radiation Therapy to the Usual Pembrolizumab Treatment for Recurrent Head and Neck CancerNational Cancer Institute (NCI)
- Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaNational Cancer Institute (NCI)
- Foot Reflexology and Ta-VNS for Symptom Management in Head and Neck Cancer During CCRTTzu Chi University
- DESTINY-PANTUMOUR04AstraZeneca
- Study Transplanting Bone Marrow Cells Into Salivary Glands to Treat Dry Mouth Caused by Radiation TherapyUniversity of Wisconsin, Madison
Research already completed
- The Use of Candy and Honey in Decreasing Salivary Gland Damage Following Radioiodine Therapy for Thyroid CancerCyprus University of Technology
- A Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid TumorsBayer
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- General Information about Salivary Gland CancerNational Cancer Institute
- Saliva and Salivary Gland DisordersNational Institute of Dental and Craniofacial Research
- Salivary Gland CancerAmerican Cancer Society
Diagnosis and Tests
- Tests for Salivary Gland CancerAmerican Cancer Society
Treatments and Therapies
- Treatment Option Overview (Salivary Gland Cancer)National Cancer Institute
Prevention and Risk Factors
- Causes, Risk Factors, and Prevention of Salivary Gland CancerAmerican Cancer Society
Living With
- After Treatment for Salivary Gland CancerAmerican Cancer Society
Clinical Trials
- ClinicalTrials.gov: Salivary Gland NeoplasmsNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Salivary Gland Neoplasms. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Salivary Gland Cancer, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.