Also called: Rachitis
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Rickets
Rickets causes soft, weak bones in children. It usually occurs when they do not get enough vitamin D, which helps growing bones absorb the minerals calcium and phosphorous. It can also happen when calcium or phosphorus levels are too low.
Your child might not get enough vitamin D if he or she:
- Has dark skin
- Spends too little time outside
- Has on sunscreen all the time when out of doors
- Doesn't eat foods containing vitamin D because of lactose intolerance or a strict vegetarian diet
- Is breastfed without receiving vitamin D supplements
- Can't make or use vitamin D because of a medical disorder such as celiac disease
In addition to dietary rickets, children can get an inherited form of the disease. Symptoms include bone pain or tenderness, impaired growth, and deformities of the bones and teeth. Your child's doctor uses lab and imaging tests to make the diagnosis. Treatment is replacing the calcium, phosphorus, or vitamin D that are lacking in the diet. Rickets is rare in the United States.
It sits within Bones, Joints and Muscles and Metabolic Problems.
The lead U.S. institute for this subject is the NIH Office of Dietary Supplements.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Rickets
271 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Phosphorus-31 Spectroscopy in Phosphate DiabetesHospices Civils de Lyon
- A Natural History Study of Bone and Mineral DisordersNational Institute of Dental and Craniofacial Research (NIDCR)
- Registry for Patients With X-Linked HypophosphatemiaKyowa Kirin Pharmaceutical Development Ltd
- Medium Cut-Off and High-Flux Membranes on Mineral and Bone Metabolism in Hemodialysis PatientsGazi University
- Early Check: Expanded Screening in NewbornsRTI International
- Morphology in Oral Rare Syndromes & Artificial Intelligence for Clinical DiagnosisUniversity Hospital, Bordeaux
Research already completed
- Study of People With Generalized Arterial Calcification of Infancy (GACI) or Autosomal Recessive Hypophosphatemic Rickets Type 2 (ARHR2)National Human Genome Research Institute (NHGRI)
- A Study to Describe the Lived Experience of XLH for Adolescents at End of Skeletal GrowthKyowa Kirin Pharmaceutical Development Ltd
- Natural History Study of ENPP1 Deficiency and the Early-onset Form of ABCC6 DeficiencyInozyme Pharma
- Calcitriol Monotherapy for X-Linked HypophosphatemiaMassachusetts General Hospital
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Learn More
- Bowlegs and Knock-KneesAmerican Academy of Pediatrics
- Mineral and Bone Disorder in Chronic Kidney DiseaseNational Institute of Diabetes and Digestive and Kidney Diseases
- RicketsNemours Foundation
- RicketsAmerican Academy of Family Physicians
- RicketsMayo Foundation for Medical Education and Research
- Vitamin DNational Institutes of Health, Office of Dietary Supplements
- Vitamin D TestNational Library of Medicine
Genetics
- Hereditary hypophosphatemic rickets: MedlinePlus GeneticsNational Library of Medicine
- Vitamin D-dependent rickets: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: RicketsNational Institutes of Health
- ClinicalTrials.gov: Rickets, HypophosphatemicNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Rickets, Rickets, Hypophosphatemic. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Rickets, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.