Also called: Post-pregnancy depression
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Postpartum Depression
Having a baby can be exciting, but it can also be stressful and bring many strong emotions. During the postpartum period, which is the time after you give birth, you may have mood swings, crying spells, or feel anxious. These feelings are common and are often called the postpartum "baby blues". The baby blues usually go away within a few days to a week.
If your symptoms are more severe and last longer than two weeks, you may have postpartum depression.
Postpartum depression is a common but serious mood disorder that can begin anytime within the first year after childbirth. Without treatment, symptoms may make it hard to care for your baby or manage daily tasks.
The exact cause is unknown, but postpartum depression likely results from a combination of factors, including:
- Sudden changes in hormone levels after pregnancy
- Physical changes, such as dropping thyroid hormone levels
- Lifestyle factors, such as fatigue, lack of sleep, limited support, or recent stressful events
Anyone can develop postpartum depression after childbirth. You might be at higher risk if you:
- Have a history of depression, bipolar disorder, or a family health history of these conditions
- Had a multiple birth (twins, triplets, or more)
- Gave birth while in your teens
- Had health problems during pregnancy
- Had preterm labor or other complications during childbirth
- Have a baby with special needs
- Have ever experienced domestic violence
- Are dealing with financial stress
- Had an unplanned pregnancy
Postpartum depression symptoms are more intense and last longer than the baby blues.
Symptoms may include:
- Feeling sad or empty most of the time
- Eating too much or too little
- Sleeping too much or too little
- Crying more than usual or for no clear reason
- Feeling unusually angry
- Pulling away from family and friends
- Feeling worried or anxious often
- Feeling little or no interest in your baby
- Constant doubts about your ability to care for your baby
- Thinking of harming yourself or your baby
If you have thoughts about suicide, or hurting yourself or your baby get help right away:
- Call 911 or go to your local emergency room
- Contact a crisis hotline. In the United States, you can reach the National Suicide and Crisis Lifeline at any time: Call or text 988
- Chat online with Lifeline Chat
- TTY users: Use your preferred relay service or dial 711 then 988
- Call 988, then press 1
- Text 838255
- Chat online
If these symptoms begin during pregnancy and continue after childbirth, it's called perinatal depression. Without treatment, it can affect bonding with your baby and may contribute to feeding or sleeping problems.
Very rarely, a new mother may develop postpartum psychosis, a medical emergency. Symptoms may include confusion, hallucinations (seeing or hearing things that aren't real), or dangerous behaviors. Call 911 or go to the nearest emergency room right away if this happens.
Your provider may diagnose postpartum depression using:
- Screening questions or questionnaires, such as those about your mood, sleep, and thoughts.
- A clinical evaluation based on your symptoms.
- Blood tests, if needed, to check for physical conditions such as thyroid disorders, that can cause or worsen depression.
If you think you have postpartum depression, talk with your provider. Treatments may include:
- Medicines, including antidepressants
- Talk therapy (counseling)
Tell your provider if you are breastfeeding so they can choose the safest treatment options.
Along with these treatment options, there are things you can do at home that may help you feel better, such as:
- Asking for help with caring for the baby and household chores
- Taking time for yourself
- Getting physical activity, such as walking
- Resting when the baby rests
You may be able to lower your risk for postpartum depression by:
- Talking with your provider during pregnancy about any history of depression
- Completing recommended screening questionnaires during pregnancy and after birth
- Getting support from family, friends, or support groups
- Attending early Physical changes so symptoms can be found and treated as soon as possible
Dept. of Health and Human Services Office on Women's Health
It sits within Women, Mental Health and Behavior and Pregnancy and Reproduction.
The lead U.S. institute for this subject is the National Institute of Mental Health.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Postpartum Depression
635 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- RCT of At-Home tDCS for Depression in PregnancyWomen's College Hospital
- Adapting a Health at Every Size Intervention to Obstetric CareUniversity of Massachusetts, Worcester
- Healing at Home 2.0 - Enhanced Chat Tool for Lowering Postpartum DepressionUniversity of Pennsylvania
- Implementation of a Clinical Decision Support Tool for Postpartum DepressionWeill Medical College of Cornell University
- A Behavioral Activation Prenatal and Postpartum Intervention for Depressed Pregnant SmokersM.D. Anderson Cancer Center
- A Study of MI078 for Postpartum DepressionNanjing Minova Pharmaceutical Co., Ltd.
Research already completed
- Preventing Childbirth-Related PTSD With Expressive WritingMassachusetts General Hospital
- A Phase 2 Study to Evaluate Efficacy and Safety of KH607 Tablets in Woman With Postpartum DepressionChengdu Kanghong Pharmaceutical Group Co., Ltd.
- A Postpartum Adaptation Study of the Connecting and Reflecting Experience Parenting ProgramMontefiore Medical Center
- Prevalence of Psychological Disorders After Immediate Postpartum HemorrhageUniversity Hospital, Clermont-Ferrand
- Prevalence of Postpartum Depression Among Patients of the CHUM GARE ClinicCentre hospitalier de l'Université de Montréal (CHUM)
- Sensing Technologies for Maternal Depression Treatment in Low-Resource SettingsGeorge Washington University
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Perinatal DepressionNational Institute of Mental Health
- Perinatal Depression in Partners: Can Both Parents Get the "Baby Blues?"American Academy of Pediatrics
- Postpartum DepressionDepartment of Health and Human Services, Office on Women's Health
- Postpartum DepressionNemours Foundation
- Postpartum DepressionMayo Foundation for Medical Education and Research
Diagnosis and Tests
- Postpartum Depression ScreeningNational Library of Medicine
Treatments and Therapies
- Antidepressants: MedlinePlus Health TopicNational Library of Medicine
- Depression TreatmentCenters for Disease Control and Prevention
- PsychotherapiesNational Institute of Mental Health
- Tips for Talking with a Health Care Professional about Postpartum DepressionDepartment of Health and Human Services, Office on Women's Health
Living With
- Guide to Identifying Support for Postpartum DepressionDepartment of Health and Human Services, Office on Women's Health
Related Issues
- Baby Blues after PregnancyMarch of Dimes Foundation
- Depression during and after Pregnancy: You Are Not AloneAmerican Academy of Pediatrics
- Help for Partners and FamiliesPostpartum Support International
- Perinatal AnxietyPostpartum Support International
- Perinatal/Postpartum Psychosis HelpPostpartum Support International
- Postpartum Post-Traumatic Stress Disorder (PTSD)Postpartum Support International
Statistics and Research
- Maternal Postpartum Depressive SymptomsFederal Interagency Forum on Child and Family Statistics
Clinical Trials
- ClinicalTrials.gov: Depression, PostpartumNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Depression, Postpartum. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Postpartum Depression, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.