Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Pheochromocytoma
Pheochromocytoma is a rare tumor that usually starts in the cells of one of your adrenal glands. Although they are usually benign, pheochromocytomas often cause the adrenal gland to make too many hormones. This can lead to high blood pressure and cause symptoms such as :
- Headaches
- Sweating
- Pounding of the heart
- Being shaky
- Being extremely pale
Sometimes pheochromocytoma is part of another condition called multiple endocrine neoplasia syndrome (MEN). People with MEN often have other cancers and other problems involving hormones.
Doctors use lab tests and imaging tests to diagnose it. Surgery is the most common treatment. Other options include radiation therapy, chemotherapy, and targeted therapy. Targeted therapy uses drugs or other substances that attack specific cancer cells with less harm to normal cells.
It sits within Cancers and Endocrine System.
The lead U.S. institute for this subject is the National Cancer Institute.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Pheochromocytoma
169 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Diagnosis of PheochromocytomaEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- Natural History Study of Children and Adults With Medullary Thyroid CancerNational Cancer Institute (NCI)
- Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant DisordersNational Cancer Institute (NCI)
- Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)Merck Sharp & Dohme LLC
- Zanzalintinib in Unresectable and Progressive MPGGsDana-Farber Cancer Institute
- Italian Multicenter Experience With Radioreceptor-assisted Therapy (PRRT)Azienda USL Reggio Emilia - IRCCS
Research already completed
- Development of a Tele-monitoring Program for Patients Undergoing Surgery for Pheochromocytoma and / or ParagangliomaAssistance Publique - Hôpitaux de Paris
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- About Pheochromocytoma and ParagangliomaEunice Kennedy Shriver National Institute of Child Health and Human Development
- General Information about Pheochromocytoma and ParagangliomaNational Cancer Institute
- PheochromocytomaMayo Foundation for Medical Education and Research
- Pheochromocytoma and ParagangliomaEunice Kennedy Shriver National Institute of Child Health and Human Development
Symptoms
- What Are Common Symptoms of Pheochromocytoma?Eunice Kennedy Shriver National Institute of Child Health and Human Development
Diagnosis and Tests
- Catecholamine TestsNational Library of Medicine
- How Do Health Care Providers Diagnose Pheochromocytoma?Eunice Kennedy Shriver National Institute of Child Health and Human Development
- Stages of Pheochromocytoma and ParagangliomaNational Cancer Institute
Treatments and Therapies
- Adrenal Gland Removal (Adrenalectomy)Society of American Gastrointestinal and Endoscopic Surgeons
- Drugs Approved for Pheochromocytoma and ParagangliomaNational Cancer Institute
- Treatment Option Overview (Pheochromocytoma and Paraganglioma)National Cancer Institute
Related Issues
- Multiple Endocrine Neoplasia Type INational Institute of Diabetes and Digestive and Kidney Diseases
Genetics
- Hereditary paraganglioma-pheochromocytoma: MedlinePlus GeneticsNational Library of Medicine
- Nonsyndromic paraganglioma: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: PheochromocytomaNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Pheochromocytoma. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Pheochromocytoma, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.