Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Ozone
Ozone is a gas. It can be good or bad, depending on where it is. "Good" ozone occurs naturally about 10 to 30 miles above the Earth's surface. It shields us from the sun's ultraviolet rays. Part of the good ozone layer is gone. Man-made chemicals have destroyed it. Without enough good ozone, people may get too much ultraviolet radiation. This may increase the risk of skin cancer, cataracts, and immune system problems.
"Bad" ozone is at ground level. It forms when pollutants from cars, factories, and other sources react chemically with sunlight. It is the main ingredient in smog. It is usually worst in the summer. Breathing bad ozone can be harmful. It can cause coughing, throat irritation, worsening of asthma, bronchitis, and emphysema. It can lead to permanent lung damage, if you are regularly exposed to it.
Environmental Protection Agency
It sits within Poisoning, Toxicology, Environmental Health.
The lead U.S. institute for this subject is the National Institute of Environmental Health Sciences.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Ozone
211 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Ozone Versus Conventional Socket Disinfection for Primary Dental Implant StabilityZeliha Başak Çakır Erdil
- Intracavernosal Exosomes vs. Rectal Ozone for Post-RARP Erectile DysfunctionMedipol University
- Impact of Major Ozone Autohemotherapy on Sarcopenia Parameters in FibromyalgiaSakarya University
- Dose-Response Effect of Intra-Articular Ozone in Knee OsteoarthritisKayseri City Hospital
- Effect of Ozone Therapy on Remineralization of Initial Caries Lesions in ChildrenNeslihan Atmaca
- Innate Immunity in Ozone-induced Airway Inflammation in COPDUniversity of California, San Francisco
Research already completed
- Effects of Ozone Therapy on Muscle DamageInonu University
- Laser Therapy Versus Ozone Therapy for Oral Mucositis in Patients With CancerUniversity of Pavia
- Effect of Systemic Ozone Therapy on Corneal EndotheliumYuzuncu Yil University
- Effect of Ozone Therapy on Marginal Bone Levels Around Dental ImplantsAdiyaman University
- Comparison Between Different Concentrations of Ozone Gas as an Intra-articular Injection for Treatment of Internal Derangement of Tempromandibular JointAlexandria University
- Different Ozone Concentrations for Knee OsteoarthritisSakarya University
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- OzoneNational Institute of Environmental Health Sciences
- Ozone Layer ProtectionEnvironmental Protection Agency
Learn More
- Air Quality Guide for OzoneEnvironmental Protection Agency
- Asthma Trigger: Air PollutionNemours Foundation
- Ground-Level Ozone PollutionEnvironmental Protection Agency
- Ozone Air Purifiers: Can They Improve Asthma Symptoms?Mayo Foundation for Medical Education and Research
- Ozone Generators That Are Sold as Air CleanersEnvironmental Protection Agency
- SunWiseEnvironmental Protection Agency
Related Issues
- AirNow.govEnvironmental Protection Agency
Clinical Trials
- ClinicalTrials.gov: Ozone ExposureNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Ozone, Stratospheric Ozone. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Ozone, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.