Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Ovarian Disorders
The ovaries are a pair of female reproductive glands that make eggs and female hormones. Women have one ovary on each side of the uterus (where a fetus grows during pregnancy). Each ovary is about the size and shape of an almond.
Ovaries play a role in menstruation, pregnancy, and menopause. Your ovaries:
- Produce and store eggs that are released during ovulation (when an egg leaves the ovary and travels into the fallopian tube). If a sperm fertilizes the egg, you can become pregnant.
- Make the female hormones estrogen and progesterone.
- Stop making those hormones and releasing eggs during menopause.
Some medical problems can affect the ovaries. These can cause various symptoms, and some ovarian disorders may need prompt treatment.
Some problems that can happen with the ovaries can include:
- Ovarian cancer is when a cancerous tumor forms in the tissues of an ovary.
- Ovarian cysts are fluid-filled sacs in or on an ovary.
- Polycystic ovary syndrome (PCOS) is a set of symptoms related to an imbalance of hormones.
- Primary ovarian insufficiency is when your ovaries stop working before age 40.
- Ovarian torsion is a twisting of the ovary.
- Endometriosis is when tissue like the lining in your uterus grows in other places in your body. It may affect the ovaries, fallopian tubes, and tissue lining the pelvis.
- Pelvic inflammatory disease is an infection and inflammation of the uterus, ovaries, and other female reproductive organs.
- Ovarian tumors.
Ovarian disorders can happen for different reasons depending on the condition. Sometimes the cause is unknown.
Your symptoms may be different, depending on the problem with your ovaries. Some ovarian disorders, such as ovarian cysts, may cause few or even no symptoms. Other disorders may cause more severe symptoms. Symptoms can include:
- Pelvic pain, which often happens during your period
- Nausea or diarrhea
- Vaginal bleeding that is between periods, very heavy, or longer than usual
- Vaginal discharge
- Painful menstrual cramps
To find out if you have a problem with your ovaries, your health care provider:
- Will ask about your medical history, including your symptoms
- Will ask about your family health history
- Will do a physical exam, including a pelvic exam
- May order imaging tests, or blood tests
Treatment depends on the ovarian disorder, your symptoms, overall health, and plans for pregnancy. Treatment can include medicines, such as pain relievers or hormonal birth control, lifestyle changes to reduce symptoms, or sometimes surgery. Ovarian cancer may require surgery, chemotherapy, or other targeted therapy.
It sits within Women and Female Reproductive System.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Ovarian Disorders
5,796 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)National Cancer Institute (NCI)
- Evaluation of Serum Preptin Levels in Patients With Polycystic Ovary SyndromeGÜLDEN ANATACA
- Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer SurvivorsUniversity of Southern California
- Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal CancerNational Cancer Institute (NCI)
- Construction of a Multi-dimensional Risk Assessment System: a Clinical Study of Polycystic Ovary Syndrome Complicated With ThrombophiliaGuangdong Women and Children Hospital
- Study of TUB-040 Given With Standard Ovarian Cancer Drugs in Patients With Fast-growing Ovarian CancerTubulis GmbH
Research already completed
- Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid TumorsNational Cancer Institute (NCI)
- Treatment of Menstrual Cycle Alterations in AdolescentsLo.Li.Pharma s.r.l
- Inositol in Letrozol Resistant PCOS WomenKafrelsheikh University
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Diagnosis and Tests
- DHEA Sulfate TestNational Library of Medicine
- Estrogen Levels TestNational Library of Medicine
- Follicle-Stimulating Hormone (FSH) Levels TestNational Library of Medicine
- LaparoscopyNational Library of Medicine
- Pelvis UltrasoundRadiological Society of North America
Treatments and Therapies
- Pelvic Venous DisordersSociety of Interventional Radiology
Genetics
- Perrault syndrome: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: Ovarian DiseasesNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Ovarian Diseases. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Ovarian Disorders, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.