Also called: MDS
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Myelodysplastic Syndromes
Your bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains immature cells, called stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting. If you have a myelodysplastic syndrome, the stem cells do not mature into healthy blood cells. Many of them die in the bone marrow. This means that you do not have enough healthy cells, which can lead to infection, anemia, or easy bleeding.
Myelodysplastic syndromes often do not cause early symptoms and are sometimes found during a routine blood test. If you have symptoms, they may include:
- Shortness of breath
- Weakness or feeling tired
- Skin that is paler than usual
- Easy bruising or bleeding
- Pinpoint spots under the skin caused by bleeding
- Fever or frequent infections
Myelodysplastic syndromes are rare. People at higher risk are over 60, have had chemotherapy or radiation therapy, or have been exposed to certain chemicals. Treatment options include transfusions, drug therapy, chemotherapy, and blood or bone marrow stem cell transplants.
It sits within Immune System.
The lead U.S. institute for this subject is the National Cancer Institute.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Myelodysplastic Syndromes
2,664 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic SyndromeChildren's Oncology Group
- Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic MalignanciesNational Cancer Institute (NCI)
- A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)Agios Pharmaceuticals, Inc.
- MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)National Cancer Institute (NCI)
- Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative NeoplasmsNational Cancer Institute (NCI)
- Natural History of Trisomy 8-Associated Autoinflammatory Disease (TRIAD) and Related DisordersNational Institute of Allergy and Infectious Diseases (NIAID)
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- General Information about Myelodysplastic SyndromesNational Cancer Institute
- General Information about Myelodysplastic/Myeloproliferative NeoplasmsNational Cancer Institute
- Myelodysplastic SyndromesMayo Foundation for Medical Education and Research
- Myelodysplastic Syndromes (MDS)NMDP
- What Are Myelodysplastic Syndromes?American Cancer Society
Diagnosis and Tests
- Blood TestsNational Heart, Lung, and Blood Institute
- Bone Marrow TestsNational Library of Medicine
- Myelodysplastic Syndrome (MDS) Prognostic Scores (Risk Groups)American Cancer Society
- Tests for Chronic Myelomonocytic Leukemia (CMML)American Cancer Society
- Tests for Myelodysplastic Syndromes (MDS)American Cancer Society
Treatments and Therapies
- Bone Marrow Transplantation: MedlinePlus Health TopicNational Library of Medicine
- General Approach to Treating Chronic Myelomonocytic Leukemia (CMML)American Cancer Society
- Treatment of Myelodysplastic SyndromesNational Cancer Institute
- Treatment Option Overview (Myelodysplastic Syndromes)National Cancer Institute
- Treatment Option Overview (Myelodysplastic/Myeloproliferative Neoplasms)National Cancer Institute
Prevention and Risk Factors
- Can Myelodysplastic Syndromes Be Prevented?American Cancer Society
- Risk Factors for Myelodysplastic Syndromes (MDS)American Cancer Society
Related Issues
- Aplastic Anemia and Myelodysplastic SyndromesNational Institute of Diabetes and Digestive and Kidney Diseases
- What Causes Myelodysplastic Syndromes?American Cancer Society
Genetics
- 5q minus syndrome: MedlinePlus GeneticsNational Library of Medicine
- What Causes Chronic Myelomonocytic Leukemia (CMML)?American Cancer Society
Statistics and Research
- Key Statistics for Myelodysplastic Syndromes (MDS)American Cancer Society
- What's New in Myelodysplastic Syndrome (MDS) Research?American Cancer Society
Clinical Trials
- ClinicalTrials.gov: Myelodysplastic SyndromesNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Myelodysplastic Syndromes. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Myelodysplastic Syndromes, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.