Also called: MS
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Multiple Sclerosis
Multiple sclerosis (MS) is a nervous system disease that affects your brain and spinal cord. It damages the myelin sheath, the material that surrounds and protects your nerve cells. This damage slows down or blocks messages between your brain and your body, leading to the symptoms of MS. They can include:
- Visual disturbances
- Muscle weakness
- Trouble with coordination and balance
- Sensations such as numbness, prickling, or "pins and needles"
- Thinking and memory problems
No one knows what causes MS. It may be an autoimmune disease, which happens when your immune system attacks healthy cells in your body by mistake. Multiple sclerosis affects women more than men. It often begins between the ages of 20 and 40. Usually, the disease is mild, but some people lose the ability to write, speak, or walk.
There is no specific test for MS. Doctors use a medical history, physical exam, neurological exam, MRI, and other tests to diagnose it. There is no cure for MS, but medicines may slow it down and help control symptoms. Physical and occupational therapy may also help.
It sits within Bones, Joints and Muscles and Brain and Nerves.
The lead U.S. institute for this subject is the National Institute of Neurological Disorders and Stroke.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Multiple Sclerosis
3,872 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- A NIS Evaluating Various Injectable and Oral Treatments in Patients With Relapsing Multiple SclerosisNovartis Pharmaceuticals
- A Study of Orelabrutinib in Patients With Secondary Progressive Multiple SclerosisZenas BioPharma (USA), LLC
- A Study of Orelabrutinib in Patients With Primary Progressive Multiple SclerosisZenas BioPharma (USA), LLC
- A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Relapsing Multiple Sclerosis (RMS)Hoffmann-La Roche
- Relationship Between Single- and Dual-Task Obstacle Crossing Performance and Fatigue and Disability in Multiple SclerosisAfyonkarahisar Health Sciences University
- Exploration of Novel Imaging Biomarkers on OCT for Ublituximab Treatment Response in Multiple SclerosisUniversity of Maryland, Baltimore
Research already completed
- A Study of Oxidative Pathways in MS FatigueUniversity of California, San Francisco
- Educational Programs Based on Healthy Habits to Improve Quality of Life and Psychosocial Profile in Women With Neurodegenerative Diseases: The ADVICE Protocol Study (Phase 1)Universidad de Almeria
- Cladribine Tablets: Collaborative Study to Evaluate Impact On Central Nervous System Biomarkers in Multiple SclerosisGregory Wu
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Multiple SclerosisMayo Foundation for Medical Education and Research
- Multiple Sclerosis (MS)National Institute of Neurological Disorders and Stroke
Diagnosis and Tests
- Cerebrospinal Fluid (CSF) AnalysisNational Library of Medicine
- CSF Immunoglobulin G (IgG) IndexNational Library of Medicine
- CSF oligoclonal banding - seriesMedical Encyclopedia
- How Is Multiple Sclerosis Diagnosed?National Multiple Sclerosis Society
Treatments and Therapies
- Disease-Modifying TherapiesNational Multiple Sclerosis Society
- Multiple Sclerosis and Complementary Health Approaches: What the Science SaysNational Center for Complementary and Integrative Health
Living With
- Advanced Multiple Sclerosis Care NeedsNational Multiple Sclerosis Society
- Comprehensive Care Approach to MSNational Multiple Sclerosis Society
- Diet and Nutrition for Multiple SclerosisNational Multiple Sclerosis Society
- Dressing with Ease, Style, and ComfortALS Association
- Exercising with Multiple SclerosisNational Multiple Sclerosis Society
- Financial Planning for Living with MSNational Multiple Sclerosis Society
- Managing Multiple Sclerosis: Treatment Can Delay Future AttacksNational Institutes of Health
- Mobility Aids: MedlinePlus Health TopicNational Library of Medicine
Related Issues
- Building Relationships and MSNational Multiple Sclerosis Society
- But You Look So Good! (Common "Invisible" MS Symptoms)National Multiple Sclerosis Society
- Depression and Multiple SclerosisNational Multiple Sclerosis Society
- Guide for Support PartnersNational Multiple Sclerosis Society
- How MS Affects the Black CommunityNational Multiple Sclerosis Society
- MyoclonusNational Institute of Neurological Disorders and Stroke
Genetics
- Multiple sclerosis: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: Multiple SclerosisNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Multiple Sclerosis. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Multiple Sclerosis, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.