Also called: Bladder pain syndrome · IC · PBS · Painful bladder syndrome
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Interstitial Cystitis
Interstitial cystitis (IC) is a condition that causes discomfort or pain in the bladder and a need to urinate frequently and urgently. It is far more common in women than in men. The symptoms vary from person to person. Some people may have pain without urgency or frequency. Others have urgency and frequency without pain. Women's symptoms often get worse during their periods. They may also have pain with sexual intercourse.
The cause of IC isn't known. There is no one test to tell if you have it. Doctors often run tests to rule out other possible causes of symptoms. There is no cure for IC, but treatments can help most people feel better. They include:
- Distending, or inflating, the bladder
- Bathing the inside of the bladder with a drug solution
- Oral medicines
- Electrical nerve stimulation
- Physical therapy
- Lifestyle changes
- Bladder training
- In rare cases, surgery
It sits within Kidneys and Urinary System.
The lead U.S. institute for this subject is the National Institute of Diabetes and Digestive and Kidney Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Interstitial Cystitis
238 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial CystitisWake Forest University Health Sciences
- Venlafaxine Combined With Education and Behavioral Intervention for Bladder Pain SyndromeBeijing Tiantan Hospital
- Bladder Directed vs. Pelvic Floor Therapy in IC/BPSCorewell Health East
- Evaluation of Hyivy Floora in Managing Interstitial Cystitis/Bladder Pain Syndrome/High-tone Pelvic Floor DysfunctionWake Forest University Health Sciences
- Safety and Preliminary Efficacy of Endoscopic Submucosal Injection of Hyaluronic Acid Into the Bladder Wall in Patients With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)Sverdlovsk Regional Clinical Hospital No.1
- Motor Cortical Neuromodulation in Women With Interstitial Cystitis/Bladder Pain SyndromeUniversity of Southern California
Research already completed
- Phenotyping Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) by Intravesical Contrast Enhanced - Magnetic Resonance Imaging (ICE-MRI) Bladder Permeability AssayChristopher J Chermansky, MD
- A Clinical Study of ONO-1110 in Patients With Hunner Type Interstitial CystitisOno Pharmaceutical Co., Ltd.
- Investigation of the Effectiveness of Acupuncture in Patients Diagnosed With Interstitial CystitisMedipol University
- Vestibulodynia: Understanding Pathophysiology and Determining Appropriate TreatmentsDuke University
- Study of V117957 in Interstitial Cystitis/Bladder Pain SyndromeImbrium Therapeutics
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Definition and Facts of Interstitial CystitisNational Institute of Diabetes and Digestive and Kidney Diseases
- Interstitial CystitisAmerican Academy of Family Physicians
- Interstitial CystitisMayo Foundation for Medical Education and Research
- Interstitial Cystitis (Bladder Pain Syndrome)National Institute of Diabetes and Digestive and Kidney Diseases
Symptoms
- Symptoms and Causes of Interstitial CystitisNational Institute of Diabetes and Digestive and Kidney Diseases
Diagnosis and Tests
- Cystoscopy and UreteroscopyNational Institute of Diabetes and Digestive and Kidney Diseases
- Diagnosis of Interstitial CystitisNational Institute of Diabetes and Digestive and Kidney Diseases
Treatments and Therapies
- Treatment of Interstitial CystitisNational Institute of Diabetes and Digestive and Kidney Diseases
Living With
- Eating, Diet, and Nutrition for Interstitial CystitisNational Institute of Diabetes and Digestive and Kidney Diseases
Clinical Trials
- ClinicalTrials.gov: CystitisNational Institutes of Health
- ClinicalTrials.gov: Cystitis, InterstitialNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Cystitis, Interstitial. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Interstitial Cystitis, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.