Health Topic

HIV

HIV (human immunodeficiency virus) attacks the body’s immune system. There is no cure but it can be treated with medicines. To know if you have HIV, get tested.

Reviewed Reviewed by a registered pharmacistGeneral information

Also called: AIDS · Acquired immunodeficiency syndrome · Human immunodeficiency virus

Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.

About HIV

HIV stands for human immunodeficiency virus. HIV harms your immune system by destroying a type of white blood cell that helps your body fight infection. This puts you at risk for other infections and diseases.

AIDS stands for acquired immunodeficiency syndrome. It is the final stage of infection with HIV. It happens when the body's immune system is badly damaged because of the virus. Not everyone with HIV develops AIDS.

HIV is spread through certain body fluids from a person who has HIV. This can happen:

  • By having unprotected vaginal or anal sex with a person who has HIV. "Unprotected" means not using condoms or medicine to treat or prevent HIV. This is the most common way that it spreads.
  • By sharing drug needles.
  • Through contact with the blood of a person with HIV.
  • From mother to fetus during pregnancy.
  • From mother to baby during, childbirth, or breastfeeding.

Anyone can get HIV, but certain groups have a higher risk of getting it:

  • People who have another sexually transmitted infection (STI). Having an STI can increase your risk of getting or spreading HIV.
  • People who inject drugs with shared needles.
  • Gay and bisexual men.
  • Black/African Americans and Hispanic/Latino Americans. They make up a higher proportion of new HIV diagnoses and people with HIV, compared to other races and ethnicities.
  • People who engage in risky sexual behaviors, such as not using condoms or medicine to prevent or treat HIV.

Factors such as stigma, discrimination, income, education, and geographic region can also affect people's risk for HIV.

The first signs of HIV infection may be flu-like symptoms:

  • Fever
  • Chills
  • Rash
  • Night sweats (heavy sweating during sleep)
  • Muscle aches
  • Sore throat
  • Fatigue
  • Swollen lymph nodes
  • Mouth ulcers

These symptoms may come and go within two to four weeks. This stage is called acute HIV infection.

If the infection is not treated, it becomes chronic HIV infection. Often, there are no symptoms during this stage. If it is not treated, eventually the virus will weaken your body's immune system. Then the infection will progress to AIDS. This is the late stage of HIV infection. Because your immune system is badly damaged, your body cannot fight off other infections, called opportunistic infections (OIs). OIs are infections that happen more frequently or are more severe in people who have weakened immune systems.

Some people may not feel sick during the earlier stages of HIV infection. So the only way to know for sure whether you have HIV is to get tested.

A blood test can tell if you have HIV infection. Your health care provider can do the test, or you can use a home testing kit. You can also use the CDC Testing Locator to find free testing sites.

There is no cure for HIV infection, but it can be treated with medicines. This is called antiretroviral therapy (ART). ART can make HIV infection a manageable chronic condition. It also reduces the risk of spreading the virus to others.

Most people with HIV live long and healthy lives if they get ART as soon as possible and stay on it. It's also important to take care of yourself. Making sure that you have the support you need, living a healthy lifestyle, and getting regular medical care can help you enjoy a better quality of life.

You can reduce the risk of getting or spreading HIV by:

  • Getting tested for HIV.
  • Choosing less risky sexual behaviors. This includes limiting the number of sexual partners you have and using latex condoms every time you have sex. If your or your partner is allergic to latex, you can use polyurethane condoms.
  • Getting tested and treated for sexually transmitted infections (STIs).
  • Not injecting drugs.
  • Talking to your provider about medicines to prevent HIV: PrEP (pre-exposure prophylaxis) is for people who don't already have HIV but are at very high risk of getting it. PrEP is daily medicine that can reduce this risk.
  • PEP (post-exposure prophylaxis) is for people who have possibly been exposed to HIV. It is only for emergency situations. PEP must be started within 72 hours after a possible exposure to HIV.

It sits within Infections and Immune System.

The lead U.S. institute for this subject is the National Institute of Allergy and Infectious Diseases.

When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.

Research on HIV

10,100 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.

What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.

Research currently under way

Research already completed

Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.

Where to read more

Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.

Start Here

Diagnosis and Tests

Treatments and Therapies

Related Issues

Statistics and Research

Clinical Trials

Men

Medical subject headings

Clinicians and researchers index this subject under HIV Infections, Acquired Immunodeficiency Syndrome. These are the terms to use when searching medical literature.

This page is built from the MedlinePlus health topic record for HIV, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.