Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Heart Disease in Women
Heart disease is a general term that includes many types of heart problems. It's also called cardiovascular disease, which means heart and blood vessel disease.
Coronary artery disease (also called coronary heart disease) is the most common type of heart disease in both men and women. It happens slowly over time when a sticky substance called plaque builds up in the arteries that supply your heart muscle with blood. The plaque narrows or blocks blood flow to the heart muscle and can lead to:
- Angina - chest pain from lack of blood flow
- Heart attacks - when part of the heart muscle dies from loss of blood flow
- Heart failure - when your heart can't pump enough blood to meet your body's needs
- Arrhythmia - a problem with the rate or rhythm of your heartbeat
In the United States, heart disease is the number one cause of death in women. But women are often not diagnosed with heart disease as quickly as men are. That's because:
- Women are more likely than men to have "silent" heart disease, meaning that they don't have symptoms.
- Health care providers may not recognize heart disease in women because women's symptoms may be different from men's symptoms.
- Women are more likely than men to have certain types of heart disease that can be harder to diagnose.
A delay in diagnosis may mean a delay in medical care that could help prevent serious problems, such as a heart attack. That's why it's important to learn about your risk for heart disease, the symptoms in women, and how to keep your heart healthy.
Women can get any type of heart disease. Like men, the most common type of heart disease among women is coronary artery disease. But there are certain types of heart disease which are less common, but affect women more often than men:
- Coronary microvascular disease - Chest pain from spasms (sudden tightening) in the smallest arteries of the heart that pinch off blood flow. It typically happens during rest or routine activities. This serious condition increases your risk of having a heart attack or other heart diseases. This type may be harder to diagnose since blockages in smaller arteries can be harder to see on imaging tests.
- Broken heart syndrome - Strong chest pain or other signs that look like a heart attack. It's caused by the stress of powerful emotions, such as deep grief, anger, or surprise. It can happen even if you're healthy. It mostly affects women after menopause and usually doesn't cause any lasting damage.
- Variant angina - A rare type of strong chest pain from spasms in the heart arteries. The pain usually happens in a pattern during sleep. Variant angina rarely causes a heart attack.
Your risk for developing heart disease increases with:
- Menopause. Women can develop heart disease at any age, but your risk increases after your periods stop, usually by age 55. Before menopause, your body makes more estrogen (a female hormone) which helps protect against heart disease. That's why women generally develop coronary artery disease 10 years later than men. During and after menopause, estrogen levels drop and your risk for heart diseases goes up. If your periods stop before age 40, your risk will be higher than other women your age.
- Family history of heart disease. Your risk for heart disease may be higher if your: Mother or sister had heart disease before age 65.
- Father or brother had heart disease before age 55.
If you have one or more risks for heart disease, ask your health care provider for help understanding your risk level. Ask if you need any heart tests to help catch heart disease early.
When women have symptoms of heart disease, they may include:
- Pain or discomfort in the chest that may be dull and heavy or sharp
- Pain in the neck, jaw, throat, upper belly, or back
- Nausea or vomiting
- Unusual fatigue
- Shortness of breath (feeling like you can't get enough air) during physical activity
Women who have coronary artery disease are more likely than men to have chest pain when resting or doing daily activities, rather than during exercise. They're also more likely than men to feel chest pain from mental stress.
Symptoms of a heart attack in women may also be different than in men. Chest pain is the most common symptom for both sexes. It may feel like crushing or squeezing. But women are somewhat less likely than men to have chest pain.
During a heart attack, women may feel:
- Pressure or tightness in the chest
- Pain in the upper back, arms, neck, jaw or throat
- Dizziness
- Unusual fatigue
- Indigestion, heartburn, nausea, or vomiting
- Stomach pain
- Shortness of breath
Heart attacks usually don't look like the sudden, dramatic events we see in the movies. The symptoms may be mild or strong. They may start slowly. They can stop and then come back.
You can help lower your risk by:
- Learning how to prevent heart disease and making heart-healthy habits part of your daily life.
- Asking your provider about your personal risk for heart disease and the best way to manage your heart health.
Remember, women can have heart disease without symptoms. But if you pay attention to your risk for heart disease, you can take action to prevent problems or keep them from getting worse.
It sits within Women and Blood, Heart and Circulation.
The lead U.S. institute for this subject is the National Heart, Lung, and Blood Institute.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Heart Disease in Women
1,438 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney DiseaseNorthwestern University
- Equity in Modifying Plaque Of WomEn With UndeRtreated Calcified Coronary Artery DiseaseShockwave Medical, Inc.
- Impact of Intraoperative Hemodynamic Instability on Outcomes in Cardiac SurgerySaglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
- Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient DisordersAscendis Pharma A/S
- Vascular Aging and Acute Kidney Injury After Cardiac SurgeryNanjing First Hospital, Nanjing Medical University
- Fluid-removal Guided by VeXUS Score With Usual Care in Patients With Acute Kidney Injury After Cardiac SurgeryHospices Civils de Lyon
Research already completed
- Sequential Cystatin C Levels and Renal Impairment in Acute Heart FailureThe Cleveland Clinic
- Identifying Risk for Diabetes and Heart Disease in WomenNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Heart DiseaseDepartment of Health and Human Services, Office on Women's Health
- Heart Health for WomenFood and Drug Administration
- The Heart TruthNational Heart, Lung, and Blood Institute
- The Heart Truth for Women: Take Action to Protect Your HeartNational Heart, Lung, and Blood Institute
Symptoms
- Heart Attack Symptoms in WomenAmerican Heart Association
Diagnosis and Tests
- Heart Health Tests: MedlinePlus Health TopicNational Library of Medicine
Prevention and Risk Factors
- Heart Disease and StrokeDepartment of Health and Human Services, Office on Women's Health
- Heart Disease in Women: Understand Symptoms and Risk FactorsMayo Foundation for Medical Education and Research
- Heart Disease Risk FactorsDepartment of Health and Human Services, Office on Women's Health
Living With
- Calcium Supplements: A Risk Factor for Heart Attack?Mayo Foundation for Medical Education and Research
- Healthy RecipesNational Library of Medicine
- Heart Attack Recovery Questions and AnswersAmerican Heart Association
- Heart Healthy EatingDepartment of Health and Human Services, Office on Women's Health
- What Is Heart-Healthy Living?National Heart, Lung, and Blood Institute
Related Issues
- Heart Conditions and Pregnancy: Know the RisksMayo Foundation for Medical Education and Research
- Heart Disease in Hispanic WomenAmerican Heart Association
- Menopause and Cardiovascular RiskAmerican Heart Association
- Pregnancy and Your Heart HealthNational Heart, Lung, and Blood Institute
- Women and Congenital Heart DefectsAmerican Heart Association
Statistics and Research
- About Women and Heart DiseaseCenters for Disease Control and Prevention
Clinical Trials
- ClinicalTrials.gov: Heart Disease in WomenNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Heart Diseases. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Heart Disease in Women, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.