Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Health Problems in Pregnancy
A health problem in pregnancy is any disease or condition that could affect your health or the health of your fetus. Some health problems may make it more likely that you will have a high-risk pregnancy. A high-risk pregnancy is one in which you, your fetus, or both are at higher risk for health problems than in a typical pregnancy.
But just because you have health problems, it doesn't mean that you, or your fetus, will have a problem during the pregnancy. Taking care of yourself and getting early and regular prenatal care from a health care provider may help you reduce pregnancy risks from health problems.
Every pregnancy has some risk of problems, but your lifestyle, as well as factors like certain conditions and health issues, can raise that risk, such as:
- A health condition you had before you got pregnant
- A health condition you develop during pregnancy
- A pregnancy with more than one baby
- A health problem that happened during a previous pregnancy and could happen again
- Substance use during pregnancy
- Being over age 35
Any of these can affect your health, the health of your fetus, or both.
Every pregnancy is different. If you have specific risks in one pregnancy, it doesn't mean that you will have them in another. But, if you have a chronic condition, you should talk to your provider about how to minimize your risk before you get pregnant. Once you are pregnant, you may need a health care team to monitor your pregnancy. Some common conditions that can complicate a pregnancy include:
- High blood pressure
- Polycystic ovary syndrome (PCOS)
- Kidney problems
- Autoimmune disorders
- Thyroid disease
- Obesity
- HIV
- Cancer
- Infections
Other conditions that may make pregnancy risky can develop during pregnancy - for example, gestational diabetes and Rh incompatibility.
You may be able to lower your risk of certain health problems by making healthy lifestyle changes before you get pregnant. These can include reaching a healthy weight, not smoking, and managing any health conditions.
However, health problems during pregnancy are not always preventable. Some chronic conditions can be treated and controlled, while others aren't treatable and carry a higher risk than usual, even if the health problem is well-managed.
Share your symptoms with your provider for early detection and treatment of health problems. Sometimes, it's hard to know what's normal. Some symptoms, like nausea, back pain, and fatigue, are common during pregnancy, while other symptoms, like vaginal bleeding or a severe or long-lasting headache, can be signs of a problem. Call your provider to let them know if something is bothering or worrying you.
It sits within Pregnancy and Reproduction and Female Reproductive System.
The lead U.S. institute for this subject is the Eunice Kennedy Shriver National Institute of Child Health and Human Development.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Health Problems in Pregnancy
24 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- E-health-supported Diagnostic and Intervention in Preterm Born Children and Their FamiliesUniversity Hospital Tuebingen
- Interdisciplinary E-health Based Follow-up of Preterm Born ChildrenUniversity Hospital Tuebingen
- JiGenerations Health Cohort Study:Parental Exposure and Intergenerational Health in ChinaNational Research Institute for Family Planning, China
- Peking University Birth Cohort in Weifang (PKUBC-WF)Peking University
- Counseling for Alcohol Problems in Pregnancy (CAP-Pre) Phase IILeibniz Institute for Prevention Research and Epidemiology - BIPS GmbH
- WhatsApp-based Psycho-socio-educational Intervention (WeLove) for Prevention of Psychological and Sleep Problems in Pregnant Women and Their Partners: A Three-arm Double-blinded Pilot Randomised Controlled TrialChinese University of Hong Kong
Research already completed
- To Evaluate the Effectiveness of a Virtual and Telephone Intervention for the Prevention of Postpartum Depression in Women at RiskSt. Justine's Hospital
- Expanding Knowledge About and Evaluating Services for Incarcerated Pregnant and Postpartum Women in ArkansasUniversity of Arkansas
- Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) StudyUniversity of California, San Francisco
- Behaviours and Emotions in PreschoolersTARGetKids!
- The Feasibility, Usability and Satisfaction of an Online Tool for Perinatal Mental Health ProblemsUniversity Hospital, Ghent
- B-vitamin Levels and Adverse Pregnancy OutcomesWestlake University
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- About High-Risk PregnancyEunice Kennedy Shriver National Institute of Child Health and Human Development
- Pregnancy ComplicationsCenters for Disease Control and Prevention
- Pregnant and Postpartum WomenCenters for Disease Control and Prevention
Diagnosis and Tests
- Estrogen Levels TestNational Library of Medicine
- Prenatal Testing: MedlinePlus Health TopicNational Library of Medicine
- Progesterone TestNational Library of Medicine
Prevention and Risk Factors
- Preventing Overheating during PregnancyNemours Foundation
Related Issues
- Asthma and PregnancyOrganization of Teratology Information Specialists
- Asthma, Allergies and PregnancyAmerican Academy of Allergy, Asthma, and Immunology
- Chronic Health Conditions and PregnancyMarch of Dimes Foundation
- Delivering Safer Pregnancies: Lower Your Risk of Health ProblemsNational Institutes of Health
- Depression and PregnancyOrganization of Teratology Information Specialists
- Family Planning and Pregnancy with Multiple SclerosisNational Multiple Sclerosis Society
- Fever/Hyperthermia and PregnancyOrganization of Teratology Information Specialists
- Gaucher Disease and PregnancyOrganization of Teratology Information Specialists
- Headaches during Pregnancy: What's the Best Treatment?Mayo Foundation for Medical Education and Research
- Heart Conditions and Pregnancy: Know the RisksMayo Foundation for Medical Education and Research
- IBS in WomenInternational Foundation for Gastrointestinal Disorders
- Lupus and PregnancyLupus Foundation of America
- Pregnancy after 35: Healthy Pregnancies, Healthy BabiesMayo Foundation for Medical Education and Research
- Pregnancy and Rheumatic DiseaseAmerican College of Rheumatology
- Providing Support for Pregnant or Postpartum WomenCenters for Disease Control and Prevention
Clinical Trials
- ClinicalTrials.gov: Pregnancy ComplicationsNational Institutes of Health
- ClinicalTrials.gov: Pregnancy, High-RiskNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Pregnancy, High-Risk, Pregnancy Complications. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Health Problems in Pregnancy, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.