Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Friedreich Ataxia
Friedreich ataxia is an inherited disease that damages your nervous system. The damage affects your spinal cord and the nerves that control muscle movement in your arms and legs. Symptoms usually begin between the ages of 5 and 15. The main symptom is ataxia, which means trouble coordinating movements. Specific symptoms include:
- Difficulty walking
- Muscle weakness
- Speech problems
- Involuntary eye movements
- Scoliosis (curving of the spine to one side)
- Heart palpitations, from the heart disease which can happen along with Friedreich ataxia
People with Friedreich ataxia usually need a wheelchair 15 to 20 years after symptoms first appear. In severe cases, people become incapacitated. There is no cure. You can treat symptoms with medicines, braces, surgery, and physical therapy.
It sits within Brain and Nerves and Genetics/Birth Defects.
The lead U.S. institute for this subject is the National Institute of Neurological Disorders and Stroke.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Friedreich Ataxia
111 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- A Study of SGT-212 Gene Therapy in Friedreich's AtaxiaSolid Biosciences Inc.
- Characterization of the Cardiac Phenotype of Friedreich's Ataxia (FRDA)Weill Medical College of Cornell University
- Digital Outcome Assessment Using AI Active Gaming and Motion Capture in Friedreich AtaxiaUniversity of Exeter
- Study of LX2006 Gene Therapy in Friedreich Ataxia CardiomyopathyLexeo Therapeutics
- Characterisation of the Cognitive Profile of Patients Suffering From Friedreich's AtaxiaInstitut National de la Santé Et de la Recherche Médicale, France
- A Study to Learn How BIIB141 (Omaveloxolone) Affects the Health of Participants With Friedrich's Ataxia Who Took it During Pregnancy and/or During Breastfeeding and About the Health of Their BabiesBiogen
Research already completed
- Characterization of the Interruptions of the GAA Expansion and Study of Their Influence on the Severity of Friedreich's AtaxiaUniversity Hospital, Montpellier
- Evaluation of the Effect of Artesunate in Friedreich Ataxia (FA)Institut National de la Santé Et de la Recherche Médicale, France
- A Study to Assess the Efficacy and Safety of Vatiquinone for the Treatment of Participants With Friedreich AtaxiaPTC Therapeutics
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Friedreich AtaxiaNational Institute of Neurological Disorders and Stroke
- Friedreich's Ataxia (FRDA)Muscular Dystrophy Association
Diagnosis and Tests
- Electromyography (EMG) and Nerve Conduction StudiesNational Library of Medicine
- Friedreich's Ataxia (FRDA): DiagnosisMuscular Dystrophy Association
- Functional MRI (fMRI)Radiological Society of North America
- Newly DiagnosedFriedreich's Ataxia Research Alliance
Treatments and Therapies
- Approved TreatmentFriedreich's Ataxia Research Alliance
- Managing Friedreich's AtaxiaFriedreich's Ataxia Research Alliance
- Treatment PipelineFriedreich's Ataxia Research Alliance
Genetics
- Friedreich ataxia: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: Friedreich AtaxiaNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Friedreich Ataxia. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Friedreich Ataxia, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.