Also called: Folacin · Folate · Pteroylglutamic acid · Vitamin B9
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Folic Acid
Folic acid is a B vitamin. It helps the body make healthy new cells. Everyone needs folic acid. For women who may get pregnant, it is really important. Getting enough folic acid before and during pregnancy can prevent major birth defects of her baby's brain or spine.
Foods with folic acid in them include:
- Leafy green vegetables
- Fruits
- Dried beans, peas, and nuts
- Enriched breads, cereals and other grain products
If you don't get enough folic acid from the foods you eat, you can also take it as a dietary supplement.
It sits within Food and Nutrition.
The lead U.S. institute for this subject is the NIH Office of Dietary Supplements.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Folic Acid
563 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.AbbVie
- Study of NALIRIFOX in Advanced Unresectable Small Bowel TumorsTiago Biachi de Castria
- A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal AdenocarcinomaAbbVie
- A Study to Evaluate Folate Receptor Alpha (FRα) Expression in Adult Participants With Ovarian, Fallopian Tube, and Primary Peritoneal Cancer in ItalyAbbVie
- A Real-world Study of Mirvetuximab Soravtansine (MIRV) in Ovarian Cancer Patients of Expression of Folate Receptor α(FRα)NING LI-GYN
- A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian CancerEli Lilly and Company
Research already completed
- Multiple Micronutrient Versus Iron-Folic Acid Supplementation in Pregnant Women in IndonesiaIndonesia Timur University
- Effects of Folic Acid and Vitamin E on Hormones in Polycystic Ovary SyndromeAl-Mustansiriyah University
- Comparison of The Effect of 5-MTHF and Folic Acid Supplementation in Increasing Red Blood Cell Folate in Pregnant WomenDr. Soetomo General Hospital
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- About Folic AcidCenters for Disease Control and Prevention
- FolateNational Institutes of Health, Office of Dietary Supplements
- Folate (Folic Acid)Mayo Foundation for Medical Education and Research
- Folic AcidDepartment of Health and Human Services, Office on Women's Health
Diagnosis and Tests
- Homocysteine TestNational Library of Medicine
- Vitamin B TestNational Library of Medicine
Genetics
- Cerebral folate transport deficiency: MedlinePlus GeneticsNational Library of Medicine
- Hereditary folate malabsorption: MedlinePlus GeneticsNational Library of Medicine
Clinical Trials
- ClinicalTrials.gov: Folic AcidNational Institutes of Health
- ClinicalTrials.gov: Folic Acid DeficiencyNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Folic Acid Deficiency, Folic Acid. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Folic Acid, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.