Also called: Grippe · Influenza · Seasonal flu
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Flu
The flu, also called influenza, is a respiratory infection caused by viruses. Each year, millions of Americans get sick with the flu. Sometimes it causes mild illness. But it can also be serious or even deadly, especially for people over 65, newborn babies, and people with certain chronic illnesses.
The flu is caused by flu viruses that spread from person to person. When someone with the flu coughs, sneezes, or talks, they spray tiny droplets. These droplets can land in the mouths or noses of people who are nearby. Less often, a person may get flu by touching a surface or object that has flu virus on it and then touching their own mouth, nose, or possibly their eyes.
Symptoms of the flu come on suddenly and may include:
- Fever or feeling feverish/chills
- Cough
- Sore throat
- Runny or stuffy nose
- Muscle or body aches
- Headaches
- Fatigue (tiredness)
Some people may also have vomiting and diarrhea. This is more common in children.
Sometimes people have trouble figuring out whether they have a cold or the flu. There are differences between them:
Sometimes people say that they have a "flu" when they really have something else. For example, "stomach flu" isn't the flu; it's gastroenteritis.
Some people who get the flu will develop complications. Some of these complications can be serious or even life-threatening. They include:
- Bronchitis
- Ear infection
- Sinus infection
- Pneumonia
- Inflammation of the heart (myocarditis), brain (encephalitis), or muscle tissues (myositis, rhabdomyolysis)
The flu also can make chronic health problems worse. For example, people with asthma may have asthma attacks while they have flu.
Certain people are more likely to have complications from the flu, including:
- Adults 65 and older
- Pregnant women
- Children younger than 5
- People with certain chronic health conditions, such as asthma, diabetes, and heart disease
To diagnose the flu, health care providers will first do a medical history and ask about your symptoms. There are several tests for the flu. For the tests, your provider will swipe the inside of your nose or the back of your throat with a swab. Then the swab will be tested for the flu virus.
Some tests are quick and give results in 15-20 minutes. But these tests are not as accurate as other flu tests. These other tests can give you the results in one hour or several hours.
Most people with the flu recover on their own without medical care. People with mild cases of the flu should stay home and avoid contact with others, except to get medical care.
But if you have symptoms of flu and are in a high risk group or are very sick or worried about your illness, contact your health care provider. You might need antiviral medicines to treat your flu. Antiviral medicines can make the illness milder and shorten the time you are sick. They also can prevent serious flu complications. They usually work best when you start taking them within 2 days of getting sick.
The best way to prevent the flu is to get a flu vaccine every year. But it's also important to have good health habits like covering your cough and washing your hands often. This can help stop the spread of germs and prevent the flu.
Centers for Disease Control and Prevention
It sits within Infections and Lungs and Breathing.
The lead U.S. institute for this subject is the National Institute of Allergy and Infectious Diseases.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Flu
2,777 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Screening for LID Clinical Studies Unit Healthy Volunteer ProtocolsNational Institute of Allergy and Infectious Diseases (NIAID)
- BPL-1357 Against H1N1 Influenza Virus ChallengeNational Institute of Allergy and Infectious Diseases (NIAID)
- Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)National Institute on Deafness and Other Communication Disorders (NIDCD)
- Study to Assess the Prophylactic Efficacy and Safety of Sebaloxavir Marboxil Tablets/Oral Suspension for Influenza Prevention in Household Contacts Aged ≥2 Years.Nanjing Zenshine Pharmaceuticals
- Influenza Vaccination Strategy for Patients With Hematologic MalignancyAsan Medical Center
- A Clinical Trial Evaluating the Safety and Efficacy of AP1189 Versus Placebo as an add-on to Standard of Care in Participants With Respiratory Insufficiency Expected to be Caused by Infection With Respiratory VirusesSynAct Pharma Aps
Research already completed
- Natural History of Systemic and Nasal Mucosal Immunity to Influenza and SARS-CoV-2 in Adults After VaccinationNational Institute of Allergy and Infectious Diseases (NIAID)
- Recombinant Influenza Vaccine Versus Standard Egg-Based Inactivated Influenza Vaccine in Adults 18-64 YearsCenters for Disease Control and Prevention
- Phase I/II Clinical Trial of Influenza Vaccine (Split Virion), Inactivated (High Dose)Sinovac Biotech Co., Ltd
- Spirulina Oral Supplement for Enhancing Host Resilience to Virus InfectionUniversity of Mississippi Medical Center
- A Safety and Immunogenicity of Intranasal Nanoemulsion Adjuvanted Recombinant Pandemic Flu Vaccine in Healthy AdultsBlueWillow Biologics
- Immunogenicity of Influenza VaccinationsDuke University
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- 2023-2024 Flu SeasonCenters for Disease Control and Prevention
- About InfluenzaCenters for Disease Control and Prevention
- Colds and the FluAmerican Academy of Family Physicians
- InfluenzaNational Institute of Allergy and Infectious Diseases
- Influenza (Flu)Mayo Foundation for Medical Education and Research
Diagnosis and Tests
- Diagnosis for FluCenters for Disease Control and Prevention
- Flu (Influenza) TestNational Library of Medicine
Treatments and Therapies
- 5 Tips: Natural Products for the Flu and Colds: What Does the Science Say?National Center for Complementary and Integrative Health
- Colds, Flu, and Complementary Health ApproachesNational Center for Complementary and Integrative Health
- Decongestants: OTC Relief for CongestionAmerican Academy of Family Physicians
- EchinaceaNational Center for Complementary and Integrative Health
- ElderberryNational Center for Complementary and Integrative Health
Prevention and Risk Factors
- Flu Prevention: Information for TravelersCenters for Disease Control and Prevention
- Healthy Habits to Help Protect against FluCenters for Disease Control and Prevention
Living With
- Caring for Someone Sick (Flu)Centers for Disease Control and Prevention
- Flu: What to Do If You Get SickCenters for Disease Control and Prevention
Related Issues
- About Cancer and FluCenters for Disease Control and Prevention
- Flu and People Living with HIVCenters for Disease Control and Prevention
- Flu and People with AsthmaCenters for Disease Control and Prevention
- Flu and People with DiabetesCenters for Disease Control and Prevention
- Flu and People with Heart Disease or History of StrokeCenters for Disease Control and Prevention
- Is It Flu, COVID-19, Allergies, or a Cold?National Institutes of Health
- It's a Good Time to Get Your Flu VaccineFood and Drug Administration
Clinical Trials
- ClinicalTrials.gov: Influenza, HumanNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Influenza, Human. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Flu, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.