Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Fistulas
A fistula is an abnormal connection between two parts inside of the body. Fistulas may develop between different organs, such as between the esophagus and the windpipe or the bowel and the vagina. They can also develop between two blood vessels, such as between an artery and a vein or between two arteries.
Some people are born with a fistula. Other common causes of fistulas include:
- Complications from surgery
- Injury
- Infection
- Diseases, such as Crohn's disease or ulcerative colitis
Treatment depends on the cause of the fistula, where it is, and how bad it is. Some fistulas will close on their own. In some cases, you may need antibiotics and/or surgery.
It sits within Digestive System and Lungs and Breathing.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Fistulas
1,133 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- Cryotherapy for Reducing Fistula Puncture Pain in Hemodialysis PatientsTaipei Medical University
- Pivotal Study of the Velocity™ pAVF SystemVenova Medical
- Okami Medical ALPHA RegistryOkami Medical, Inc.
- Myriad™ Augmented Soft Tissue Reconstruction RegistryAroa Biosurgery Limited
- Effect of 4-7-8 Breathing on AV Fistula Needle Pain in Dialysis PatientsIzmir Kavram Vocational School
- Antibiotics After Incision and Drainage to Prevent Fistula Formation After First Episode of Perianal AbscessUniversity of Illinois at Chicago
Research already completed
- Radiofrequency-assisted Transection of the Pancreas vs StaplerPatricia Sanchez Velazquez
- Virtual Reality Distraction for Pain and Anxiety in Hemodialysis PatientsKarbala University
- Esophageal Protection Study: A Multicenter StudyAdvanced Cooling Therapy LLC, d/b/a Attune Medical
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
- Fistulas: Genitourinary and RectovaginalAmerican Urogynecologic Society
Diagnosis and Tests
- Computed Tomography (CT) EnterographyRadiological Society of North America
- Fistulogram/SinogramRadiological Society of North America
- Lower GI Series (Barium Enema)National Institute of Diabetes and Digestive and Kidney Diseases
- MR EnterographyRadiological Society of North America
Treatments and Therapies
- Embolization of Brain Aneurysms and Arteriovenous Malformations/FistulasRadiological Society of North America
- Endoscopic Fistula Closure in the Gastrointestinal (GI) TractJohns Hopkins Medicine
- Intracranial Vascular TreatmentsRadiological Society of North America
Clinical Trials
- ClinicalTrials.gov: FistulaNational Institutes of Health
Medical subject headings
Clinicians and researchers index this subject under Fistula. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Fistulas, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.