Also called: Senility
Important: This page is general information, not medical advice. It does not recommend or prescribe any treatment. Always consult your doctor or pharmacist before starting, stopping or changing any medicine.
About Dementia
Dementia is a loss of mental functions that is severe enough to affect your daily life and activities. These functions include:
- Memory
- Language skills
- Visual perception (your ability to make sense of what you see)
- Problem solving
- Trouble with everyday tasks
- The ability to focus and pay attention
It is normal to become a bit more forgetful as you age. But dementia is not a normal part of aging. It is a serious disorder that interferes with your daily life.
The most common types of dementia are known as neurodegenerative disorders. These are diseases in which the cells of the brain stop working or die. They include:
- Alzheimer's disease, which is the most common form of dementia among older people. People with Alzheimer's have plaques and tangles in their brain. These are abnormal buildups of different proteins. Beta-amyloid protein clumps up and forms plaques in between your brain cells. Tau protein builds up and forms tangles inside the nerve cells of your brain. There is also a loss of connection between nerve cells in the brain.
- Lewy body dementia, which causes movement symptoms along with dementia. Lewy bodies are abnormal deposits of a protein in the brain.
- Frontotemporal disorders, which cause changes to certain parts of the brain: Changes in the frontal lobe lead to behavioral symptoms
- Changes in the temporal lobe lead to language and emotional disorders
Other conditions can cause dementia or dementia-like symptoms, including:
- Creutzfeldt-Jakob disease, a rare brain disorder
- Huntington's disease, an inherited, progressive brain disease
- Chronic traumatic encephalopathy (CTE), caused by repeated traumatic brain injury
- HIV-associated dementia (HAD)
Certain factors can raise your risk for developing dementia, including:
- Aging. This is the biggest risk factor for dementia.
- Smoking
- Uncontrolled diabetes
- High blood pressure
- Drinking too much alcohol
- Having close family members who have dementia
The symptoms of dementia can vary, depending on which parts of the brain are affected. Often, forgetfulness is the first symptom. Dementia also causes problems with the ability to think, problem solve, and reason. For example, people with dementia may:
- Get lost in a familiar neighborhood
- Use unusual words to refer to familiar objects
- Forget the name of a close family member or friend
- Forget old memories
- Need help doing tasks that they used to do by themselves
Some people with dementia cannot control their emotions and their personalities may change. They may become apathetic, meaning that they are no longer interested in normal daily activities or events. They may lose their inhibitions and stop caring about other peoples' feelings.
Certain types of dementia can also cause problems with balance and movement.
The stages of dementia range from mild to severe. In the mildest stage, it is just beginning to affect a person's functioning. In the most severe stage, the person is completely dependent on others for care.
Your health care provider may use many tools to make a diagnosis:
- A medical history, which includes asking about your symptoms
- A physical exam
- Tests of your thinking, memory, and language abilities
- Other tests, such as blood tests, genetic tests, and brain scans
- A mental health evaluation to see whether a mental disorder is contributing to your symptoms
There is no cure for most types of dementia, including Alzheimer's disease and Lewy body dementia. Treatments may help to maintain mental function longer, manage behavioral symptoms, and slow down the symptoms of disease. They may include:
- Medicines, which may temporarily improve memory and thinking or slow down their decline. They only work in some people. Other medicines can treat symptoms such as anxiety, depression, sleep problems, and muscle stiffness. Some of these medicines can cause strong side effects in people with dementia. It is important to talk to your health care provider about which medicines will be safe for you.
- Occupational therapy to help find ways to more easily do everyday activities
- Speech therapy to help with swallowing difficulties and trouble speaking loudly and clearly
- Mental health counseling to help people with dementia and their families learn how to manage difficult emotions and behaviors. It can also help them plan for the future.
- Music or art therapy to reduce anxiety and improve well-being
Researchers have not found a proven way to prevent dementia. Living a healthy lifestyle might influence some of your risk factors for dementia.
It sits within Mental Health and Behavior, Older Adults and Brain and Nerves.
The lead U.S. institute for this subject is the National Institute on Aging.
When to speak to someone. Reading about a topic cannot tell you whether it applies to you. Speak to a doctor or pharmacist if symptoms are severe, sudden, getting worse, or simply not going away — and seek emergency care immediately for chest pain, breathing difficulty, sudden weakness or confusion, or a serious allergic reaction.
Research on Dementia
6,552 studies areregistered for this condition on ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. A selection is below — the links go straight to the registry entry, not to a summary of ours.
What a registered study does and does not mean. Registration means a study exists and has been declared publicly. It says nothing about whether the treatment being tested works, is safe, or is available to you. Many studies find no benefit — that is what research is for. Never seek out an experimental treatment on the strength of a registry entry alone.
Research currently under way
- MIBG in Aging and Neurologic DisordersMayo Clinic
- A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Integrating Systematic Data of Medicine to Explore the Solution for Healthy Aging (ISDHA) Phase 4Chang Gung Memorial Hospital
- ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)Mayo Clinic
- Amyloid PET Imaging in the Baltimore Longitudinal Study of AgingNational Institute on Aging (NIA)
- Genetic Characterization of Movement Disorders and DementiasNational Institute on Aging (NIA)
Research already completed
- Inherited Diseases, Caregiving, and Social NetworksNational Human Genome Research Institute (NHGRI)
- Deprescribing in Patients Living With Dementia With Caregiver and Provider NudgesBrigham and Women's Hospital
- Impact of COVID-19 Vaccines on Cerebrovascular HealthChinese University of Hong Kong
- University of Central Florida Music StudyUniversity of Central Florida
- Electroconvulsive Therapy (ECT) for Agitation in Dementia (AD)Brent Forester
- Using a Wireless Controller to Deliver a Lighting Intervention to Persons With DementiaIcahn School of Medicine at Mount Sinai
Study data from ClinicalTrials.gov, a service of the U.S. National Library of Medicine. Retrieved 2026-07-30. Registry entries are supplied by study sponsors and investigators; ClinicalTrials.gov does not verify their scientific validity. PocketsInfo is not affiliated with, and not endorsed by, the NLM or the NIH.
Where to read more
Rather than paraphrase, we point you to the primary sources. Every link below is to a government health agency, a national institute or a recognised medical body — grouped by what you are trying to find out.
Start Here
Diagnosis and Tests
- Cognitive Impairment in Older Adults: ScreeningU.S. Preventive Services Task Force
- Dementia: Diagnosis and TestsAGS Health in Aging Foundation
Treatments and Therapies
- 7 Things To Know About Dietary Supplements for Cognitive Function, Dementia, and Alzheimer's DiseaseNational Center for Complementary and Integrative Health
Prevention and Risk Factors
- Brain HealthAlzheimer's Association
- Brain Training: Cognitive Health Tips for SeniorsAmerican Academy of Family Physicians
- Can I Prevent Dementia?Department of Health and Human Services
Living With
- Finding Dementia Care and Local ServicesDepartment of Health and Human Services
Related Issues
- Brain Donation: A Gift for Future GenerationsNational Institute on Aging
- Brain HealthNational Institute on Aging
- Caring for a Person with a Frontotemporal DisorderNational Institute on Aging
- Dementia and DrivingFamily Caregiver Alliance
Genetics
- Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: MedlinePlus GeneticsNational Library of Medicine
- Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy: MedlinePlus GeneticsNational Library of Medicine
- CHMP2B-related frontotemporal dementia: MedlinePlus GeneticsNational Library of Medicine
- Dementia with Lewy bodies: MedlinePlus GeneticsNational Library of Medicine
- Frontotemporal dementia with parkinsonism-17: MedlinePlus GeneticsNational Library of Medicine
- GRN-related frontotemporal lobar degeneration: MedlinePlus GeneticsNational Library of Medicine
- Inclusion body myopathy with early-onset Paget disease and frontotemporal dementia: MedlinePlus GeneticsNational Library of Medicine
Statistics and Research
- Caregivers of a Person with Alzheimer's Disease or a Related DementiaCenters for Disease Control and Prevention
- FastStats: Alzheimer's DiseaseNational Center for Health Statistics
Clinical Trials
- ClinicalTrials.gov: DementiaNational Institutes of Health
- Find Clinical TrialsDepartment of Health and Human Services
Medical subject headings
Clinicians and researchers index this subject under Dementia. These are the terms to use when searching medical literature.
This page is built from the MedlinePlus health topic record for Dementia, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health. Information is from MedlinePlus.gov. PocketsInfo is not affiliated with, and is not endorsed by, the NLM or the NIH. Retrieved 30 July 2026.